A5046182014- Blood Pressure and Hypertension Studies
- Chronic Kidney Disease and Diabetes
- Diabetes Treatment and Management
- Cardiovascular Health and Disease Prevention
- Cardiovascular Health and Risk Factors
- Diabetes Management and Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Function and Risk Factors
- Pharmacology and Obesity Treatment
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Hormonal Regulation and Hypertension
- Cardiac Health and Mental Health
- Renin-Angiotensin System Studies
- Cardiovascular and exercise physiology
- Health Literacy and Information Accessibility
- Pharmaceutical Practices and Patient Outcomes
- Dialysis and Renal Disease Management
- Health Promotion and Cardiovascular Prevention
- Cerebrovascular and Carotid Artery Diseases
- Health disparities and outcomes
- Mobile Health and mHealth Applications
- Neurological and metabolic disorders
- Health Policy Implementation Science
- Medication Adherence and Compliance
University of Colorado Denver
2009-2024
Denver Health Medical Center
2009-2024
University of Colorado Boulder
2024
University of Colorado Anschutz Medical Campus
1997-2024
Health and Hospital Corporation
2015-2023
The Medical Center of Aurora
2015
University of Colorado Health
1997-2012
Kaiser Permanente
2009-2010
Denver Public Health
2009
St. Mary-Corwin Medical Center
2006
It has recently been reported that the use of calcium-channel blockers for hypertension may be associated with an increased risk cardiovascular complications. Because this issue remains controversial, we studied incidence such complications in patients non-insulin-dependent diabetes mellitus and who were randomly assigned to treatment either blocker nisoldipine or angiotensin-converting–enzyme inhibitor enalapril as part a larger study.
Background— Secondhand smoke exposure increases the risk of acute myocardial infarction (AMI). One study (Helena, Mont) examined issue and found a decrease in AMI associated with smoke-free ordinance. We sought to determine impact ordinance on admission rates another geographically isolated community (Pueblo, Colo). Methods Results— assessed hospitalizations Pueblo during 3-year period, 1.5 years before after implementation compared hospitalization among individuals residing within city...
Background— Peripheral arterial disease (PAD) and diabetes are both associated with a high risk of ischemic events, but the role intensive blood pressure control in PAD has not been established. Methods Results— The Appropriate Blood Pressure Control Diabetes study followed 950 subjects type 2 for 5 years; 480 were normotensive (baseline diastolic 80 to 89 mm Hg). Patients randomized placebo (moderate control) had mean 137±0.7/81±0.3 Hg over last 4 years treatment. In contrast, patients...
The relationship between urinary albumin excretion (UAE) and diabetic complications in NIDDM has not been studied a large American population. demonstrated increased UAE the development of retinopathy, nephropathy, neuropathy IDDM makes this an important issue to also be patients.A population study 947 patients living predominantly metropolitan area was undertaken. Three categories UAE, namely, normal albuminuria (< 20 micrograms/min), microalbuminuria (20-200 overt (> 200 micrograms/min)...
Although many studies have identified patient characteristics or chronic diseases associated with medication adherence, the clinical utility of such predictors has rarely been assessed. We attempted to develop prediction rules for adherence antihypertensive medications in 2 healthcare delivery systems.We performed retrospective cohort hypertension registries an inner-city system (n=17 176) and a health maintenance organization (n=94 297) Denver, Colo. Adherence was defined by acquisition 80%...
Objectives. We evaluated whether a program to prevent coronary heart disease (CHD) with community health workers (CHWs) would improve CHD risk in public and care settings. Methods. The CHWs provided point-of-service screening, education, coordination residents 34 primarily rural Colorado counties. utilized motivational interviewing navigated those at for into medical lifestyle resources. A software application generated real-time 10-year Framingham Risk Score (FRS) guideline-based...
OBJECTIVE Exercise capacity has been used as a noninvasive parameter for predicting cardiovascular events. It demonstrated previously in NIDDM patients that several risk factors (i.e., obesity, smoking, hypertension, and African-American race) are associated with an impaired exercise capacity. We studied 265 male 154 female who underwent graded testing expired gas analyses to determine the possible influences of diabetic neuropathy, nephropathy, retinopathy on RESEARCH DESIGN AND METHODS...
Background— Risk factors for cardiovascular disease (CVD) derived from the Framingham study are widely used to guide preventive efforts. It remains unclear whether these risk predict CVD death in racial/ethnic minorities as well they do predominately white cohorts. Methods and Results— Using linked data National Health Nutrition Examination Survey III (1988 1994) Death Index, we developed Cox proportional hazard models that predicted time separately non-Hispanic (NHW), black (NHB), Mexican...
Key Points Renin-angiotensin system inhibition was favorable for risk of kidney failure (compared with 0% decline use placebo or other agents) up to declines in eGFR 13% over a 3-month period. Relation between after renin-angiotensin inhibitor initiation and outcomes stronger the first 2 years follow-up waned time. Background Declines GFR occur commonly when (RAS) inhibitors are started. Our objective determine relation during trials RAS outcomes. Methods We included participants CKD (eGFR...