- Bipolar Disorder and Treatment
- Liver Diseases and Immunity
- Liver Disease Diagnosis and Treatment
- Healthcare Decision-Making and Restraints
- Multiple Sclerosis Research Studies
- Cleft Lip and Palate Research
- Psychosomatic Disorders and Their Treatments
- Palliative Care and End-of-Life Issues
- Gallbladder and Bile Duct Disorders
- Adolescent and Pediatric Healthcare
- Schizophrenia research and treatment
- Tracheal and airway disorders
- Down syndrome and intellectual disability research
- Congenital Diaphragmatic Hernia Studies
- Urban Transport and Accessibility
- Child and Adolescent Psychosocial and Emotional Development
- Religion, Spirituality, and Psychology
- COVID-19 and healthcare impacts
- Cystic Fibrosis Research Advances
- Mental Health Treatment and Access
- Sexuality, Behavior, and Technology
- Intellectual Capital and Performance Analysis
- Health, psychology, and well-being
- Health Promotion and Cardiovascular Prevention
- Stuttering Research and Treatment
St George's, University of London
2022
Population Health Research Institute
2022
University of London
2022
University College London
2014-2021
Marie Curie
2019-2021
Royal Free London NHS Foundation Trust
2020
Bunkyo University
2020
ASrid
2020
Boehringer Ingelheim (United States)
2020
Aetion (United States)
2020
Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming available in the past years. There need for reference tool compiling current data to aid professionals treatment decisions. Objectives: To develop an evidence-based clinical practice guideline pharmacological of people MS. Methods: This has been developed using Grading Recommendations Assessment, Development and Evaluation (GRADE) methodology following updated EAN recommendations. Clinical questions were...
Background and purpose Multiple sclerosis ( MS ) is a complex disease with new drugs becoming available in the past years. There therefore need for reference tool compiling current data to aid professionals treatment decisions. The objective was develop an evidence‐based clinical practice guideline pharmacological of people . Methods This has been developed using GRADE methodology following updated EAN recommendations development. Clinical questions were formulated PICO format (patient,...
Bipolar disorder is a complex, recurrent, and severe mental illness that has an onset typically between 13 30 years of age lifetime prevalence 1.4%.1 It characterised by episodes mania or hypomania with elation, overactivity, disinhibited behaviour, as well depression profound loss interest motivation, often milder depressed mood in episodes. associated increased risk suicide physical illness, such ischaemic heart disease, diabetes, chronic obstructive airways pneumonia, unintentional...
Clinical responsiveness to cognitive behavioural therapy for psychosis (CBTp) varies. Recent research has demonstrated that illness perceptions predict active engagement in therapy, and, thereby, better outcomes. In this study, we aimed investigate the psychometric properties of a modification Illness Perceptions Questionnaire (M-IPQ) designed response following CBTp.Fifty-six participants with persistent, distressing delusions completed M-IPQ; forty before brief CBT intervention targeting...
This is one of a series BMJ summaries new guidelines based on the best available evidence; they highlight important recommendations for clinical practice, especially where uncertainty or controversy exists.It relatively common people with learning disability to develop behaviour that challenges.In educational, health, and social care settings, prevalence rates challenging in disabilities vary from 10% 15%, 1 2 peaking between ages 20 49 years.Rates are higher more severe within inpatient...
Primary sclerosing cholangitis (PSC) is a rare incurable disease of the bile ducts and liver which can significantly impair quality life (QoL). No existing QoL tools are entirely suitable for people living with PSC (PwPSC). We aimed to develop measure PwPSC in UK, beginning by identifying relevant issues. This paper describes our approach this first stage, discusses related benefits limitations.Scientific consensus on how reliably stage lacking, due its rarity heterogeneity. initially...
Abstract Background Parents of children who have a congenital anomaly can experience significant worry about their child’s health. Access to clear, helpful, and trustworthy information provide valuable source support. In this study the aim was explore needs parents/carers with anomalies across Europe. Method A cross-sectional online survey developed in nine languages measure parents’ needs, including: (1) ‘helpfulness’/’trustworthiness’ received from eight relevant sources, (2) overall...
Aims:We are developing a new measure of quality life (QoL), the UK-PSC-QoL, for people with primary sclerosing cholangitis (PSC), rare incurable disease bile ducts and liver which can considerably impact QoL.Method: Following initial issue generation reduction, 83 issues in six domains were constructed as items.The resulting provisional UK-PSC-QoL was then pilot-tested PwPSC UK.Consensus on how to reliably stage PSC is lacking, so we hypothesised eight categories relating severity,...
Objective To survey parents and carers of children with a congenital anomaly across Europe about their experiences healthcare services support during the COVID-19 pandemic. Design Cross-sectional study. Setting Online in 10 European countries, open from 8 March 2021 to 14 July 2021. Population 1070 aged 0–10 years cleft lip, spina bifida, heart defect (CHD) requiring surgery and/or Down syndrome. Main outcome measures Parental views about: provision care for child (cancellation/postponement...
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Abstract Background Parents of children who have a congenital anomaly can experience significant worry about their child’s health. Access to clear, helpful, and trustworthy information provide valuable source support. In this study the needs parents/carers with anomalies were explored across Europe. Method A cross-sectional online survey was developed in nine languages measure parents’ needs, including: (1) ‘helpfulness’/’trustworthiness’ received from eight relevant sources, (2) overall...
This paper will report on the methodology for a new UK study of aviation night-noise exposure health. Funded by United Kingdom Department Transport (DfT), is examining effects range night-time periods sleep disturbance and annoyance. The involves cross-sectional survey 4000 participants living near eight airports to assess associations aircraft noise at night subjective annoyance, as well an objective 170 participants, where physiological assessments be linked participant’s home. deliver...