A5011186953- Respiratory viral infections research
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Pneumonia and Respiratory Infections
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Viral gastroenteritis research and epidemiology
- Viral Infections and Vectors
- Global Health and Surgery
- Inflammatory Bowel Disease
- Influenza Virus Research Studies
- Patient-Provider Communication in Healthcare
- Antibiotic Use and Resistance
- Patient Dignity and Privacy
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Anomalies and Fetal Surgery
- COVID-19 Clinical Research Studies
- Microscopic Colitis
- COVID-19 epidemiological studies
- Genetic factors in colorectal cancer
- Cystic Fibrosis Research Advances
- COVID-19 Impact on Reproduction
- Frailty in Older Adults
- Advances in Oncology and Radiotherapy
Vanderbilt University Medical Center
2023-2025
Massachusetts General Hospital
2020-2024
Harvard University
2020-2024
University of Jordan
2018-2021
Abstract Background Lymph node ratio (LNR) may offer superior prognostic stratification in colorectal adenocarcinoma compared with N stage. However, candidate cutoff ratios require validation. We aimed to study the significance of LNR and its optimal ratio. Methods reviewed pathology records all patients stage III who were managed at King Hussein Cancer Center between January 2014 December 2019. then studied clinical characteristics patients, correlates lymph count, positive nodes, value...
Abstract Background Adult hematopoietic cell transplant (HCT) recipients are at high risk of influenza complications but have suboptimal immune responses to vaccines. Our previous phase II trial in adult HCT demonstrated that two doses high-dose trivalent vaccine (HD-TIV) were associated with higher hemagglutination inhibition (HAI) antibody than standard-dose quadrivalent (SD-QIV), similar safety profiles. This sub-study aims characterize immunogenicity and this vaccination strategy...
Abstract Objectives The etiology of biliary atresia (BA) is unclear and potentially involves viral triggers. We aimed to compare the incidence BA in United States before during coronavirus disease 2019 (COVID‐19) pandemic, focusing on potential associations with circulation disruptions caused by nonpharmaceutical interventions (NPIs). Methods queried Pediatric Health Information System® (PHIS) for all patients discharged between January 1, 2010, 31, 2024. Using CDC WONDER, we calculated...
Abstract Background Human parainfluenza viruses (PIV) are a major cause of acute respiratory infection (ARI) leading to hospitalization in young children. In order quantify the burden PIV hospitalizations and evaluate characteristics children hospitalized with by virus type, we used data from New Vaccine Surveillance Network (NVSN), multicenter, active, prospective population-based surveillance network, enrolling for ARI (defined as fever and/or symptoms) at 7 U.S. children’s hospitals....
Risk factors for severe respiratory syncytial virus (RSV) illness include early infancy, premature birth, and underlying medical conditions. However, the clinical significance of viral co-detection is unclear. We compared outcomes young children with RSV-only detection those RSV co-detection. conducted active, population-based surveillance medically attended fever or symptoms at 7 US centers (1 December 2016-31 March 2020). Demographic data were collected through parental interviews chart...
Abstract Background Multimodal treatment is the standard of care for rectal adenocarcinoma, with a subset patients achieving pathologic complete response (pCR). While pCR associated improved overall survival (OS), long‐term data on limited. Methods This single institution retrospective cohort study all clinical stages II/III adenocarcinoma who underwent neoadjuvant chemoradiation therapy and operative resection (January 1, 2004–December 31, 2017). PCR was defined as no tumor identified in...
Abstract Background Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infections in young children worldwide. With the recent wave regulatory approvals and authorizations for nirsevimab maternal RSV vaccines across several countries, understanding current burden seasonality crucial implementing effective preventive strategies globally. We aimed to determine burden, seasonality, co-detections hospitalized < 2 years old Amman, Jordan.Figure 1.Monthly proportion...
ABSTRACT Inappropriate antibiotic use drives antimicrobial resistance, a global health threat causing increased morbidity and mortality. Understanding practices in low-resource settings is essential to identify intervention targets. This study investigates prescription Amman, Jordan. We conducted three prospective viral surveillance studies at the largest public hospital Jordan (2010–2013, 2020, 2023) included children <2 years old hospitalized with fever or respiratory symptoms. The data...
Autism spectrum disorder (ASD) describes a range of neurodevelopmental disabilities that impair behavior and communication. Although it is relatively prevalent, the pathophysiology still subject to speculation debate. The aim this study identify possible association between interleukin-6, -8, -9, -10 tumor necrosis factor alpha (TNF-α) in autism among Jordanian children by comparing plasma levels these cytokines autistic with those their unaffected siblings unrelated healthy controls.In...
Background Patterns of respiratory syncytial virus (RSV) co-detection with other viruses may have been disrupted during the coronavirus disease 2019 (COVID-19) pandemic, but clinical impact viral co-detections RSV is not well-established. We aimed to explore frequency and outcomes associated single detection before pandemic. Methods conducted a single-center retrospective cohort study all children adults samples tested using pathogen panel (RPP; 01/01/2018–11/30/2022), provider-ordered...
Abstract Introduction Antibiotic misuse is associated with the emergence of antimicrobial-resistant bacteria. It therefore important to limit antibiotic use for respiratory infections, especially those that are virus-associated. In developing countries, without point-of-care testing common viruses (e.g., syncytial virus, or RSV), clinicians rely on clinical judgment relay judgement distinguish between viral and bacterial causes illness. We sought evaluate patterns in young, hospitalized...
Screening and early detection reduce morbidity mortality in colorectal cancer. Our aim is to study the effect of income disparities on clinical characteristics patients with cancer Massachusetts.Patients were extracted from a database containing all surgically treated cancers between 2004 2015 at tertiary hospital Massachusetts. We split into 2 groups: "above-median income" "below-median according median Massachusetts ($74,167).The analysis included 817 patients. The above-median group...
Abstract Background Antimicrobial resistance (AMR) contributes to substantial morbidity and mortality. The misuse overuse of antibiotics are major drivers AMR. Lack point-of-care testing discern viral from bacterial infections complicates appropriate management in low-resource settings. This study examines antibiotic prescription practices Amman, Jordan. Methods We conducted three prospective surveillance studies at the largest public hospital Amman Jordan (2010–2013, 2020, 2023). Our target...
This report aims to investigate the attitudes of physicians in Jordan towards non-disclosure health information among physicians, with a focus on those who are 'always truthful' and not.The is based second subset data from cross-sectional study-conducted between January August 2016-of truth disclosure practices Jordan. The sample consisted 240 selected four major hospitals by stratified random sampling invited complete self-administered questionnaire regarding attitudes. were compared not.A...
The ideal time interval between the completion of chemoradiotherapy and subsequent surgical resection advanced stage rectal tumors is highly debated. Our aim to study effect on postoperative oncologic outcomes in cancer.Patients who underwent neoadjuvant for resected locally 2004 2015 were included this analysis. was calculated from date radiation surgery. Patients split into 2 groups based (<8 weeks >8 weeks). Postoperative (anastomotic leak, pathologic complete response (pCR), readmission)...
Fibroepithelial polyps are benign tumors of mesodermal origin that usually arise on the surface skin and to a lesser extent in urinary tract; however, their presence penis is extremely unusual. We report case 73-year-old male with an large broad-based penile fibroepithelial polyp (FEP) involving shaft glans associated chronic condom catheter use was treated partial penectomy. A review literature included highlight rarity this case. To best our knowledge, largest mass its kind be reported penis.