A5022247657- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Inflammasome and immune disorders
- Autoimmune and Inflammatory Disorders Research
- Salivary Gland Disorders and Functions
- Cell Adhesion Molecules Research
- T-cell and B-cell Immunology
- Retinal and Optic Conditions
- Eosinophilic Esophagitis
- Bone health and treatments
- Atherosclerosis and Cardiovascular Diseases
- Vasculitis and related conditions
- Rheumatoid Arthritis Research and Therapies
- Connective tissue disorders research
- Streptococcal Infections and Treatments
- Osteoarthritis Treatment and Mechanisms
- IL-33, ST2, and ILC Pathways
- Diabetes and associated disorders
- Galectins and Cancer Biology
- Otitis Media and Relapsing Polychondritis
- Renal Diseases and Glomerulopathies
- Vitamin D Research Studies
- Liver Diseases and Immunity
- Educational Methods and Analysis
- Psoriasis: Treatment and Pathogenesis
Ankara University
2006-2024
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2014
Istanbul Medeniyet University
2014
Medical College of Wisconsin
1994-2001
Lutheran Hospital
1991
Oslo University Hospital
1991
Objective: Behçet's disease (BD) is a multisystemic inflammatory disorder classified among the vasculitides, which can affect all types and sizes of blood vessels. Vascular involvement may be seen in 25–50% BD patients. In this study, we examined characteristics vascular patients with BD.Methods: One hundred eighty were included study. The diagnosis was made on clinical signs, by Doppler ultrasonography and/or angiography using computed tomographic or magnetic resonance techniques where...
Berntzen HB, Ölmez U, Fagerhol MK, Munthe E. The Leukocyte Protein L1 in Plasma and Synovial Fluid from Patients with Rheumatoid Arthritis Osteoarthritis. Scand J Rheumatol 1991; 20: 74-82.L1 is a major granulocyte monocyte protein, released during activation turnover of such cells. Blood synovial fluid (SF) 41 patients rheumatoid arthritis (RA) 6 osteoarthritis (OA), were analyzed for the acute phase proteins C-reactive orosomucoid, haptoglobin, α1-antitrypsin albumin as well differential...
Ölmez Ü, Turgay M, Özenirler S, Tutkak H, Düzgün N, Duman Tokgöz G. Association of HLA Class I and II Antigens with Rheumatic Fever in a Turkish Population. Scand J Rheumatol 22: 49–52.The distribution class antigens 100 patients rheumatic fever, 77 whom had cardiac involvement, was examined. We compared the results control group identical origin. The frequency A10 B35 were found significantly higher fever (p<0.05. p<0.01, respectively). DRw11 involvement than those without (p<0.05, On other...
Objectives: Behçet's disease (BD) is an inflammatory disease, characterized by oral aphthous lesions, recurrent uveitis, skin and genital ulcerations. Increased release of several cytokines may play a role in the stages BD. IL-33, member IL-1 cytokine superfamily, plays important inflammation. We analyzed serum IL-33 concentration BD patients to assess its possible pathophysiology this disease.Methods: The study included 54 patients, 31 with active 23 inactive as well 18 matched healthy...
Complement activation products, C9 and C3-containing circulating immune complexes (CIC), were evaluated in plasma synovial fluid (SF) from patients with rheumatoid arthritis (RA) osteoarthritis. C3 products the phase terminal complement complex considerably elevated SF RA reaching levels five- to eighttimes that plasma, consistant a local of whole cascade joints. The results emphazise importance detecting by neoepitope expression instead single fragment determinations. concentration native...
Abstract Background Behçet's disease (BD) is an inflammatory disorder characterized by oral aphthous lesions, uveitis, and genital ulcerations. The vitamin D receptor (VDR) has a crucial role in the pathogenesis of this because it mediates functions immune system. Alterations VDR expression related to polymorphic alleles gene may play pathogenic BD BD's clinical presentations. Methods 150 patients healthy controls were included genotyping was carried out polymerase chain reaction/restriction...
Abstract Background Association of psoriasis vulgaris with HLA antigens reference to age at onset has been reported in different racial or ethnic populations. Objective Our purpose was determine the distribution markers Turkish population according vulgaris. Methods class I and II were performed by serologic methods a group 100 patients 201 control subjects. Patients subdivided into two groups based on (below above 40 years age) family history. Results The frequency A30, Cw3, Cw6, DR7, DR14,...
Abstract We evaluated intrarenal arterial waveforms with image‐directed color Doppler ultrasonography in 21 patients systemic lupus erythematosus (SLE). The systolic–diastolic ratio, resistive index, and pulsatility index were compared serum creatinine levels, clearance, quantitation of urinary protein excretion, as well histopathologic scores specimens obtained from 9 who underwent renal biopsy. parameters the normal ranges all patients, without showing significant correlation any or...
Sjogren's syndrome (SS) is an autoimmune disease characterized by lymphocytic and plasma cell infiltration of lacrimal salivary glands. Behçet's (BD) a systemic recurrent orogenital apthous ulcerations eye lesions like iridocyclitis. In this report, we describe case that has both SS BD associated with AA type amyloidosis. The patient was 70-year-old female who been diagnosed for twenty-two years ten years. She complained nausea, vomiting, leg swelling nocturia the last few months. Duodenal...
Objective: Behçet's disease (BD) is a chronic, multisystemic inflammatory disorder with an unknown etiology.T cells are crucial in the pathogenesis of BD.Janus kinase-2 (JAK2) and signal transducer activator transcription 3 (STAT3) intracellular transduction molecules that increase risk developing some autoimmune diseases.By modifying Th1 Th17 responses, JAK2 STAT3 signaling pathways believed to be effective BD.This study aimed determine whether BD Turkish population related polymorphisms....