A5016793123- Renal cell carcinoma treatment
- Renal and related cancers
- Bladder and Urothelial Cancer Treatments
- Cancer Genomics and Diagnostics
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Sarcoma Diagnosis and Treatment
- Testicular diseases and treatments
- Genital Health and Disease
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Genetic and Kidney Cyst Diseases
- Pediatric Urology and Nephrology Studies
- Medical Imaging and Pathology Studies
- Cancer-related Molecular Pathways
- IgG4-Related and Inflammatory Diseases
- Ovarian cancer diagnosis and treatment
- Tuberous Sclerosis Complex Research
- Neuroblastoma Research and Treatments
- Cancer, Lipids, and Metabolism
- Neuroendocrine Tumor Research Advances
- Epigenetics and DNA Methylation
Albany Medical Center Hospital
2016-2025
Brigham and Women's Hospital
2019-2025
Harvard University
2019-2025
University Hospitals of Cleveland
2018-2022
Indiana University School of Medicine
2020
Indiana University – Purdue University Indianapolis
2020
The University of Texas MD Anderson Cancer Center
2019
Alexandria University
2019
Minneapolis Institute of Arts
2018
Case Western Reserve University
2015-2016
Low-grade oncocytic tumour (LOT) of the kidney has recently emerged as a potential novel type. Despite similarity to oncocytoma or eosinophilic chromophobe renal cell carcinoma, it shows diffuse keratin 7 immunohistochemistry (IHC) and negative KIT (CD117), which differs from both. We aimed identify molecular characteristics these tumours. Seventeen tumours (one male, 16 female, nine previously published) fitting original description this entity (solid morphology, often with areas cells...
Transcription factor E3-rearranged renal cell carcinoma (TFE3-RCC) has heterogenous morphologic and immunohistochemical (IHC) features.131 pathologists with genitourinary expertise were invited in an online survey containing 23 questions assessing their experience on TFE3-RCC diagnostic work-up.Fifty (38%) participants completed the survey. 46 of 50 reported multiple patterns, most commonly papillary pattern (almost always 9/46, 19.5%; frequently 29/46, 63%). Large epithelioid cells abundant...
Given the diverse clinical progression of prostate cancer (PC) and evolving significance histopathological factors in its management, this study aimed to explore impact cribriform pattern 4 (CP4) on outcomes PC patients examine molecular characteristics. This retrospective analyzed data from The Cancer Genome Atlas (TCGA) database included who underwent radical prostatectomy (RP) had pathology slides available for assessment CP4. A multivariable competing risk regression analysis was used...
Based on the eighth edition of American Joint Committee Cancer staging system, postpubertal germ cell tumors (GCT) and malignant sex cord-stromal (SCST) testis invading hilar soft tissue are pathologic stage pT2. Adipose is typically used as an anatomical landmark by pathologists for determining invasion. Herein, we evaluated presence, location, extent intratesticular fat in a multi-institutional cohort orchiectomies. Consecutive orchiectomies from 3 academic institutions were reviewed (n =...
Due to their association with the kidney, adrenal glands are frequently resected by urologists and evaluated genitourinary (GU) pathologists. However, given growing complexity of pathology advent a dedicated "endocrine pathology" subspecialty, herein we sought assess sentiment regarding among GU One hundred twenty-eight pathologists who handle specimens participated in survey including both junior (40% < 10 years practice) experienced (60% > 11 practice), work academic (75%) or private...
Introduction: Prostate cancer (PCa) is the most common malignant tumor in men, with acinar adenocarcinoma as predominant subtype. While PCa metastases typically affect bones, penile are exceedingly rare. Penile tumors generally squamous cell carcinoma (SCC), p16 overexpression often used a surrogate marker for oncogenic human papillomavirus (HPV) infection. Case Presentation: We report case of an 85-year-old male history (grade group 5) treated irradiation and hormonal therapy, who presented...
Epithelioid angiomyolipoma (eAML) is an uncommon subtype of angiomyolipoma, a subset which can demonstrate malignant behavior. While some studies have proposed histopathologic features predictive aggressive behavior in eAML, there limited data on the use immunohistochemistry (IHC) and/or next-generation sequencing (NGS) to identify biomarkers for poor clinical outcome. Moreover, genetic dichotomy (tuberous sclerosis complex [ TSC ] alteration versus TFE3 rearrangement) eAML....