A5103047039- Drug-Induced Adverse Reactions
- Autoimmune Bullous Skin Diseases
- Mast cells and histamine
- Urticaria and Related Conditions
- Radioactivity and Radon Measurements
- Mesenchymal stem cell research
- Pancreatitis Pathology and Treatment
- PI3K/AKT/mTOR signaling in cancer
- Bioinformatics and Genomic Networks
- Radiation Dose and Imaging
- Systemic Lupus Erythematosus Research
- Monoclonal and Polyclonal Antibodies Research
- Advanced Adaptive Filtering Techniques
- Gene expression and cancer classification
- Cancer, Hypoxia, and Metabolism
- Diagnosis and treatment of tuberculosis
- Amoebic Infections and Treatments
- RNA modifications and cancer
- Immune Cell Function and Interaction
- Vitamin D Research Studies
- Radiation Therapy and Dosimetry
- Speech and Audio Processing
- Hematopoietic Stem Cell Transplantation
- Indoor and Outdoor Localization Technologies
- Pluripotent Stem Cells Research
Xihua University
2024
Fudan University
2005-2022
Huashan Hospital
2015-2022
Methazolamide (MTZ) has been occasionally linked to the lethal Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which are associated with HLA-B*59:01. However, some MTZ-induced SJS/TEN (MTZ-SJS/TEN) cases negative for HLA-B*59:01, implying that other genetic factors besides HLA-B*59:01 contributing MTZ-SJS/TEN.To comprehensively identify HLA non-HLA susceptibility MTZ-SJS/TEN in Han Chinese.Eighteen patients MTZ-SJS/TEN, 806 subjects of population control 74 MTZ-tolerant...
Background Accumulating evidence suggests that the AKT/mTOR pathway plays an important role in pathogenesis of systemic lupus erythematosus (SLE) through activating T cells, and there are few studies looking into microRNA (miRNAs) mechanism. We first found miR-633 expression CD4 + cells SLE patients was significantly reduced. Objective To investigate cells. Methods Samples 17 cases 16 healthy controls were collected to detect miR-633, AKT1, mTOR mRNA proteins by quantitative polymerase chain...
Most human cancers are characterized by genomic instability. Changes associated with such may result in altered expression of numerous genes. The sequence information available the public databases can be used to identify transcripts differentially expressed cancers. Determining cancer-related genes that commonly deregulated different tumor types facilitate identification targets for cancer diagnoses and therapeutic treatments. Using a data-mining tool named Digital Differential Display...
Wearing lead X-ray-protective aprons is a routine in nuclear medicine department parts of China. However, the staff are often perplexed by questions such as if it imperative to wear when injecting radioactive drugs, how much radiation dosage can be shielded and apron will produce secondary instead? To answer these questions, semiconductor detector was employed record different gamma X-ray spectra with without or sheet. Then, we could estimate signal shielding ratio photons for compare...
Objective: To summarize the clinical features of patients with Klebsiella pneumoniae pyogenic liver abscess(KP-PLA). Methods: Clinical data 133 abscess(PLA) and positive results blood or pus culture were retrospectively analyzed in Huashan Hospital Affiliated to Fudan University from 2009 2018. According results, divided into KP-PLA group (n=92) non-KP-PLA (n=41). Results: similar gender composition males accounting for 67.39% 70.73%, had age (56.8±13.8) years (55.0±13.0) (χ(2)=0.146, 0.708,...
Objective: To summarize the etiology of primary adrenal insufficiency (PAI) and analyze its clinical features. Methods: A retrospective analysis was performed in Department Endocrinology, Peking Union Medical College Hospital from October 1981 to June 2019. Patients with PAI as first symptom were enrolled. The analyzed characteristics also summarized. Results: total 131 patients enrolled, including 87 males 44 females (57 adolescents, 74 adults). age ranged 0 73 years. cause adolescents...