A5023566771- Health Systems, Economic Evaluations, Quality of Life
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical Economics and Policy
- Pharmaceutical Practices and Patient Outcomes
- Health, Medicine and Society
- Antibiotic Use and Resistance
- Biosimilars and Bioanalytical Methods
- Ethics in Clinical Research
- Healthcare Systems and Practices
- Pharmaceutical industry and healthcare
- Biomedical Ethics and Regulation
- Patient-Provider Communication in Healthcare
- Drug-Induced Adverse Reactions
- Influenza Virus Research Studies
- Patient Safety and Medication Errors
- Meta-analysis and systematic reviews
- Pharmaceutical studies and practices
- Pharmaceutical Quality and Counterfeiting
- SARS-CoV-2 and COVID-19 Research
- Aging, Elder Care, and Social Issues
- COVID-19 Clinical Research Studies
- Pain Management and Opioid Use
- Urinary Tract Infections Management
- Pneumonia and Respiratory Infections
- Antibiotics Pharmacokinetics and Efficacy
Université Paris-Est Créteil
2009-2025
Hôpital Intercommunal de Créteil
2019-2025
Agence Nationale de Sécurité du Médicament et des Produits de Santé
2014-2024
Centre Hospitalier Universitaire de Besançon
2021
Hôpital Cochin
2021
Assistance Publique – Hôpitaux de Paris
2013-2021
Centre Hospitalier Universitaire de Nice
2021
Lebanese University
2019-2021
Epidemiology in dermatology and evaluation of therapeutics
2021
ESME - École d’ingénieurs pluridisciplinaires
2021
The aims of the present study were to describe consumption trends three groups analgesics (non-opioids, and mild strong opioids) between 2006 2015 in France, compare this pattern use with six European countries 2015.Annual drugs sales extracted from French national authority's database, IMS Multinational Integrated Data Analysis System databases for countries.The opioids France was found have decreased by 53% over past 10 years, owing declining dextropropoxyphene combinations, along an...
Nanomaterials are present in a wide variety of health products, drugs and medical devices their use is constantly increasing, varying terms diversity quantity. The topic vast because it covers nanodrugs, but also excipients (that includes proportions NMs) (with intended or not-intended (by-products wear) nanoparticles). Although researchers the field nanomedicines clinical research industry push for clearer definitions relevant regulations, endeavor challenging due to enormous NMs specific...
Artificial intelligence tools promise transformative impacts in drug development. Regulatory agencies face challenges integrating AI while ensuring reliability and safety clinical trial approvals, marketing authorizations, post-market surveillance. Incorporating these technologies into the existing regulatory framework agency practices poses notable challenges, particularly evaluating data models employed for purposes. Rapid adaptation of regulations internal processes is essential to keep...
Objectives The aim was to provide figures for drug shortages in France and describe their characteristics, causes trends between 2012 2018. Methods Data from the national reporting system Agency of Medicine Health Product Safety (ANSM) analysed. This database contains information regarding effective predicted major therapeutic interest drugs (ie, whose shortage would be life-threatening or representing a loss treatment opportunity patients with severe disease) which are mandatory reported by...
The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and subsequent disease 2019 (COVID-19) pandemic with continuous evolution virus into variants such as Alpha, Beta, Delta, Omicron others necessitates an on-going surveillance evaluation vaccine effectiveness (VE).This study focuses on assessing real-world performance Pfizer-BioNTech (BNT162b2) against variant. This employs a test-negative, case-control design, methodology commonly utilized for estimating...
International guidelines on ethics in biomedical research require that the informed consent of all enrolled participants is obtained. A written document describing research, (IC) document, must be given to by investigator. Most IC documents are long, containing much information. The aim present study was determine whether modification a working group or systematic improvement its lexicosyntactic readability can improve comprehension information patients participating research.One hundred and...
Abstract Writing an informed consent form (ICF) for biomedical research is a difficult task. We conducted multicenter single‐blind randomized controlled trial to identify whether working group or the systematic improvement in lexico‐syntactic readability association of two could increase comprehension written information given healthy volunteers enrolled research. Participants were read one four versions ICF: unchanged ICF (A), with (B), modified by (C), and followed (D). The primary...
The aim was to evaluate the comprehension of participants an improved informed consent document (ICD).
Medication error is a global threat to patient safety, particularly in pediatrics. Yet, this issue remains understudied population, both hospital and community settings.To characterize medication errors involving pediatrics reported the French Error Guichet, compare them with adults, each of settings.This was retrospective secondary data analysis throughout 2013-2017. Descriptive multivariate analyses were performed actual potential reports between (aged <18 years) adults >18 <60 years). Two...
A C TThis study aims to evaluate the antibiotic prescribing rate for acute bacterial rhinosinusitis in community pharmacies and corresponding attitude behavior of participants.A cross-sectional, nationwide was conducted using a patient-simulated case rhinosinusitis.Descriptive data were reported medications prescribed, questions asked, recommendations made.Bivariate analysis identify factors affecting aforementioned.Out 250 visited, 77 (30.8%) prescribed antibiotics, 15 (6%) referred patient...
Influenza epidemics cause around 3 to 5 million cases of severe illness worldwide every year. Estimates are needed for a better understanding the burden disease especially in low- and middle-income countries. The objective this study is estimate number rate influenza-associated respiratory hospitalizations Lebanon during five influenza seasons (2015-2016 2019-2020) by age province residence addition estimating level severity.
Shortages of drugs and medical devices have tended to increase in France worldwide, with consequences for patients healthcare professionals. Preventing shortages health products has become a priority regulatory authorities, including the French National Agency Medicines Health Products Safety (ANSM). To highlight perspectives better prevention, we described analyzed management availability over last 10 years. The supply chain was mapped identify main causes stakeholders involved managing...
Urinary tract infections are considered as one of the most frequent bacterial in community and hospital settings. In this era increasing antimicrobial resistance, stewardship has become highly important struggle to preserve effectiveness available drugs. One main causes antibiotic resistance is inappropriate prescribing antibiotics; which evidence show that pharmacists contribute to.This study aims evaluate rate responses contact persons pharmacies assess conformity prescribed antibiotics...
Because patients and patient organizations want to strengthen their role in the care pathway drug evaluation order improve pharmacovigilance activities, European competent authorities implemented regulations allow direct reporting of adverse reactions related medicinal products by 2012.
Because patients who are to undergo surgery must give their consent planned postoperative care, clear and complete information on pain management should be given. The aim of this quality-of-care study was evaluate by inquiry the impact written describing quality type retained, patient participation in discussing agreeing programme during presurgical anaesthesiology consultation.Prospective before after interventional surveys, each lasting 3 weeks conducted at a 6-month interval (time...