A5024340639- Hepatitis B Virus Studies
- Oral Health Pathology and Treatment
- Diabetes and associated disorders
- Diabetes Management and Research
- Telomeres, Telomerase, and Senescence
- Pancreatic function and diabetes
- Vitamin D Research Studies
- Liver Disease Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Head and Neck Cancer Studies
- Hepatitis C virus research
- Birth, Development, and Health
- Probiotics and Fermented Foods
- Bone health and osteoporosis research
- Oral microbiology and periodontitis research
- Respiratory viral infections research
- Parasitic infections in humans and animals
- Cancer Genomics and Diagnostics
- Tuberculosis Research and Epidemiology
- Nutrition, Genetics, and Disease
- Salivary Gland Disorders and Functions
- Vitamin C and Antioxidants Research
- Hematological disorders and diagnostics
- HIV/AIDS Research and Interventions
- Gestational Diabetes Research and Management
Ziauddin University
2015-2024
University of Glasgow
2023
Creative Commons
2023
Ziauddin Hospital
2021
Baqai Medical University
2020
Baqai Institute of Diabetology and Endocrinology
2020
University of Minnesota
2020
Patel Hospital
2020
University of Malaya
2016
University of the Sciences
2015
Although Plasmodium vivax usually causes benign uncomplicated malaria, it can occasionally result in severe disease with life-threatening, end-organ involvement generally seen falciparum malaria. We report a case of cerebral malaria caused by P. and review the literature on this subject.
As the hepatitis B genotyping is important for assessing its clinical implications and geographical distribution, sub-genotypes have been found useful determination of specific genomic markers related to hepatocarcinogenesis. In Pakistan, there no reported data on molecular evolutionary analysis HBV. A study was, therefore, much needed evaluate spectra mutations present in strains prevalent here. confirm specificity PCR typing, phylogenetic pre-S1 region divergence was studied through 13...
The aim of the present study was to assess and compare clinical efficacy local probiotic Lactobacillus reuteri (L. reuteri) systemic antibiotics as adjunct scaling root planing (SRP) in treatment chronic periodontitis (CP).Thirty systemically-healthy participants (15 15 antibiotic), clinically diagnosed with CP, were enrolled. All patients underwent SRP. Adjunctive probiotics administered twice daily for 3 months, whereas a combination amoxicillin metronidazole given three times 7...
Abstract Taenia crassiceps cysticercosis results in an impressive feminization male mice during chronic infection, characterized by increased serum estradiol levels 100 times their normal values, while those of testosterone and dihydrotestosterone are decreased 85 95% respectively. Concomitantly, the follicle-stimulating hormone IL-6 70 90 values infected mice. Since a specific Th1/Th2 shift immune response has been previously reported this may be associated with process, we proposed that is...
Introduction The aim of the study was to explore association between intake specific food substances and sleeping patterns medical students. Methods A cross-sectional conducted with 440 students, aged 18-24 years, chosen through non-probability consecutive sampling from Karachi, Pakistan. Pittsburgh sleep quality index (PSQI) used measure a self-made questionnaire that categorized foods according their nutritional constitutions frequency consumption. Associations were evaluated using...
Genetic variations in TLR7 could modulate the severity of COVID-19. Objectives: To find association between mRNA expression, genotypic variations, and disease COVID-19 patients. Methods: A cross-sectional observational study was conducted on 59 PCR-confirmed patients at Ziauddin Hospital, Karachi (June 2022–May 2023). Blood samples were analyzed for genotyping via PCR Sanger sequencing. Disease classified into three groups based clinical guidelines. expression quantified using real-time...
This review explores various methods for detecting BRCA1 and BRCA2 mutations, including Array Comparative Genomic Hybridization (aCGH), Denaturing High-Performance Liquid Chromatography (DHPLC), Digital PCR, High-Resolution Melting Analysis (HRMA), Multiple Ligation-dependent Probe Amplification (MLPA), Next-Generation Sequencing (NGS) & NGS-panels, RNA methods, Sanger Sequencing. The search used articles published between 2018 2023, focusing on genetic testing BRCA mutations techniques...
Genotyping of HBV is generally used for determining the epidemiological relationship between various virus strains and origin infection mostly in research studies. The utility genotyping clinical applications only beginning to gain importance. Whether will constitute part evaluation Hepatitis B patients depends largely on availability relevance evidence based information. Since Pakistan has a genotype distribution which been considered less virulent as investigated by earlier studies from...
This study aimed at determining the association between serum neuregulin 4 (NRG4) and insulin in gestational diabetes mellitus (GDM) their correlation with other metabolic parameters. A cross-sectional was conducted from June 2018 to February 2019 Ziauddin University, Karachi. Pregnant women (n = 80), 24-28 weeks of gestation, were recruited. Demographic data, anthropometric measurements antenatal history recorded. The fasting blood drawn for testing sugar (FBS), NRG4, lipid profile....
Infection of the central nervous system by Taenia solium cysticerci is cause human neurocysticercosis, a major neurological infection in Third World and an emerging infectious disease United States. We previously isolated cysteine proteinase from crassiceps demonstrated that it degrades IgG vitro . have now 48 kDa thiol-dependent T. The enzyme also IgG, but does not significantly degrade albumin. degradation was inhibited inhibitors, inhibitors aspartic, serine, or metalloproteinases....
Background: Zinc transporter 8 autoantibody (ZnT8A), discovered through bioinformatics, is identified as another major biomarker for type 1 diabetes mellitus (T1DM), expanding the panel of diagnostic autoantibodies. The absence standard autoantibodies in T1DM patients and presence ZnT8A individuals before disease development has led researchers to evaluate gather information about frequency its association. Therefore, we aim find out concentration association with T1DM. Methods: A...