A5103050857- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
- Hepatitis B Virus Studies
- Systemic Lupus Erythematosus Research
- Oral microbiology and periodontitis research
- Inflammasome and immune disorders
- Blood groups and transfusion
- Chemokine receptors and signaling
- Reliability and Agreement in Measurement
- Advanced Glycation End Products research
- Signaling Pathways in Disease
- Pituitary Gland Disorders and Treatments
- Autophagy in Disease and Therapy
- Proteoglycans and glycosaminoglycans research
- Corneal surgery and disorders
- Cytomegalovirus and herpesvirus research
- Liver Disease Diagnosis and Treatment
- Adrenal Hormones and Disorders
- Glaucoma and retinal disorders
- Mast cells and histamine
- Ophthalmology and Eye Disorders
- Healthcare and Venom Research
- Lung Cancer Research Studies
Capital Medical University
2024
Beijing Tongren Hospital
2024
Changhai Hospital
2009-2021
Second Military Medical University
2009-2021
Ruijin Hospital
2016
Binzhou Medical University
2012
Binzhou University
2012
Rheumatoid arthritis (RA) is a complex and not fully understood autoimmune disease associated with multijoint damage. The main effector cells, the synovial fibroblasts, are apoptosis resistant hyperplastic which indicate that autophagy level high in tissue. Real-time PCR, immunocytochemistry, western blotting were used this paper to study status of tissues obtained from RA OA patients at time joint replacement surgery. We further evaluated correlation between levels activity-associated serum...
Abstract IL -10 is widely accepted as a survival, proliferation, and differentiation factor for B cells. However, IL-10 deficiency accelerates disease progression the result of autoantibody production in many autoimmune models. It was demonstrated that T follicular helper cells (TFH cells) play key role helping are secreting Abs. In this study, we regulatory IL-10R signaling on development cell help function TFH vitro vivo. IL-1R subunit β-deficient (Il10rb−/−) Th were able to differentiate...
Periodontitis is a chronic inflammatory disease associated with gram-negative subgingival microflora infection. Accumulating experimental evidence suggests that escin exerts anti-inflammatory and anti-edematous effects. This study was designed to investigate the in vitro effects of on reaction human periodontal ligament cells (hPDLs). hPDLs were stimulated lipopolysaccharide (LPS). The treated various concentrations escin. viability evaluated using MTT method. expression Toll-like receptor 2...
Journal Article Diagnostic accuracy of anti-alpha-fodrin antibodies for primary Sjögren's syndrome Get access Qin Qin, Department Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China Search other works by this author on: Oxford Academic Google Scholar Hui Wang, Wang Huai-Zhou Yuan-Lan Huang, Huang ChinaDepartment Changzheng P.R. Hu Li, Li Wei-Wei Zhang, Zhang Jian-Rong Ling-Ling He, He Rheumatology and Immunology, Rong Xia, Xia Transfusion,...
Abstract To evaluate the feasibility of serum HMGB1, anti-HMGB1 antibodies, and HMGB1/anti-HMGB1 ratio as a diagnosis indicator initial clinical classification in patients with fever unknown origin (FUO). Ninety-four classical FUO ninety healthy controls were enrolled this study. The subjects’ data collected. concentration HMGB1 was detected by commercial ELISA kit, while antibodies an in-house built kit further confirmed immunoblotting. According to hospital on discharge, ninety-four...
B and T lymphocyte attenuator ( BTLA),a most recently identified inhibitory receptor of the CD28 superfamily,is unusual in that its ligand is not one classic B7 family members,but a tumor necrosis factor (TNFR) superfamily member,herpes virus entry mediator (HVEM).HVEM also has another ligand,lymphotoxin-like,exhibits inducible expression,and competes with HSV glycoprotein D for HVEM ,a expressed by lymphocytes( LIGHT),a member TNF superfamily.HVEM was considered as molecular switch because...
Pro-gastrin-releasing peptide (ProGRP) is the promising molecular tumor marker of small cell lung cancer (SCLC). Here we study influence different blood samples treatment methods on ProGRP.Serum with and without separation gel heparin plasma from 10 SCLC patients 5 healthy individuals were assayed for ProGRP immediately 2, 4, 6, 8, 24, 48 hours after collection.ProGRP serum detected was basically consistent, whereas there a significant difference in level them 2 hours. No variation time...