A5045557746- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Salmonella and Campylobacter epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial infections and disease research
- Escherichia coli research studies
- Mycobacterium research and diagnosis
- Bacterial biofilms and quorum sensing
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Streptococcal Infections and Treatments
- Parasitic Infections and Diagnostics
- Clostridium difficile and Clostridium perfringens research
- Probiotics and Fermented Foods
- Vibrio bacteria research studies
- Genomics and Phylogenetic Studies
- Aquaculture disease management and microbiota
- Antibiotics Pharmacokinetics and Efficacy
- Listeria monocytogenes in Food Safety
- Animal Disease Management and Epidemiology
- Veterinary medicine and infectious diseases
- Microbial Metabolism and Applications
- Child Nutrition and Water Access
- Food Safety and Hygiene
Murdoch University
2016-2025
The University of Adelaide
2013-2019
Pathwest Laboratory Medicine
2018
Bethel College
2018
New South Wales Department of Primary Industries
2011-2015
University of Wollongong
2010-2014
Agricultural Institute
2011
The Wistar Institute
1982
Abstract Objectives Antimicrobial resistance (AMR) to critically important antimicrobials (CIAs) amongst Gram-negative bacteria can feasibly be transferred wildlife, humans and domestic animals. This study investigated the ecology, epidemiology origins of CIA-resistant Escherichia coli carried by Australian silver gulls (Chroicocephalus novaehollandiae), a gregarious avian wildlife species that is common inhabitant coastal areas with high levels human contact. Methods Sampling locations were...
Journal Article Colonial Morphology of Staphylococci on Memphis Agar: Phase Variation Slime Production, Resistance to β-Lactam Antibiotics, and Virulence Get access Gordon D. Christensen, Christensen Search for other works by this author on: Oxford Academic PubMed Google Scholar Larry M. Baddour, Baddour Bereneice Madison, Madison Joseph T. Parisi, Parisi Soman N. Abraham, Abraham David L. Hasty, Hasty Jon H. Lowrance, Lowrance A. Josephs, Josephs W. Andrew Simpson The Infectious Diseases,...
Methicillin-resistant coagulase-positive staphylococci (CoPS) have become increasingly recognised as opportunistic pathogens that limit therapeutic options in companion animals. The frequency of methicillin resistance amongst clinical isolates on an Australia-wide level is unknown. This study determined antimicrobial susceptibility patterns for CoPS isolated from infections animals (dogs, cats and horses) part the first nation-wide survey animal Australia a one-year period (January 2013 to...
Carbapenem-resistant Enterobacteriaceae (CRE) are a pressing public health issue due to limited therapeutic options treat such infections. CREs have been predominantly isolated from humans and environmental samples they rarely reported among companion animals. In this study we report on the isolation plasmid characterization of carbapenemase (IMP-4) producing Salmonella enterica Typhimurium animal. Carbapenemase-producing S. carrying blaIMP-4 was identified systemically unwell (index) cat...
Pigs have been recognised as a reservoir of livestock associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in Europe, Asia and North America. However, little is known about the presence distribution MRSA Australian pig population industry. This study describes presence, molecular characteristics human adapted CA-MRSA ST93 isolated from pigs, people, environment within piggery. Isolates were subjected to antibiotic susceptibility testing, DNA microarray, whole genome sequencing,...
Unlike Escherichia coli strains belonging to phylogroup B2, the clinical significance of F is not well understood. Here we report on a collection recovered in Australia from faeces and extra-intestinal sites humans, companion animals native animals, as poultry meat water samples. The distribution sequence types was clearly non-random with respect isolate source. antimicrobial resistance virulence trait profiles also varied type isolate. Phylogroup tended lack traits typically associated B2...
In a structured survey of all major chicken-meat producers in Australia, we investigated the antimicrobial resistance (AMR) and genomic characteristics
Escherichia coli sequence types 131 (ST131) and 1193 are multidrug-resistant extraintestinal pathogens that have recently spread epidemically among humans occasionally isolated from companion animals. This study characterized a nationwide collection of fluoroquinolone-resistant (FQ R ) E. isolates infections in Australian cats dogs. For this, 59 cat dog FQ clinical (representing 6.9% an 855-isolate collection) underwent PCR-based phylotyping whole-genome sequencing (WGS). Isolates...
Most new pathogens of humans and animals arise via switching events from distinct host species. However, our understanding the evolutionary ecological drivers successful adaptation, expansion, dissemination are limited. Staphylococcus aureus is a major bacterial pathogen leading cause mastitis in dairy cows worldwide. Here we trace history bovine S. using global dataset 10,254 genomes including 1,896 isolates 32 countries 6 continents. We identified 7 contemporary endemic clones causing...
Treatment with 12-O-tetradecanoyl-phorbol-13-acetate (TPA) of acute myeloblastic leukemia cells halts proliferation and induces expression monocyte/macrophage markers. Surface characteristics leukemic HL60 cells, as defined using a panel monoclonal antibodies, were found to be similar those normal human promyelocytes. TPA treatment, however, induced phenotype that, unlike monocytes, contained several myeloid-specific markers lacked monocyte-specific treatment causes the rapid disappearance...
Abstract This study investigated the ecology, epidemiology and plasmid characteristics of extended-spectrum cephalosporin (ESC)-resistant E. coli in healthy pigs over a period 4 years (2013–2016) following withdrawal ESCs. High carriage rates ESC-resistant were demonstrated 2013 (86.6%) 2014 (83.3%), compared to 2015 (22%) 2016 (8.5%). ESC resistance identified among isolates was attributed an IncI1 ST-3 (pCTXM1-MU2) encoding blaCTXM-1. Genomic characterisation selected (n = 61) movement...
This study investigated the frequency of antimicrobial non-susceptibility (defined as isolates with minimum inhibitory concentrations above CLSI susceptible clinical breakpoint) among E. coli and Salmonella spp. isolated from healthy Australian finisher pigs. (n = 201) 69) were cecal contents slaughter-age pigs, originating 19 farms distributed throughout Australia during July-December 2015. Isolates underwent concentration (MIC) susceptibility testing to 11 antimicrobials. The highest...