Basile Pache

ORCID: 0000-0003-0969-7345
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About
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Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Enhanced Recovery After Surgery
  • Nutrition and Health in Aging
  • Intraperitoneal and Appendiceal Malignancies
  • Colorectal Cancer Surgical Treatments
  • Cervical Cancer and HPV Research
  • Endometrial and Cervical Cancer Treatments
  • Colorectal and Anal Carcinomas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Appendicitis Diagnosis and Management
  • Hemodynamic Monitoring and Therapy
  • Ovarian cancer diagnosis and treatment
  • Nausea and vomiting management
  • Hip and Femur Fractures
  • Frailty in Older Adults
  • Surgical site infection prevention
  • Renal cell carcinoma treatment
  • Genital Health and Disease
  • Abdominal Trauma and Injuries
  • Pelvic and Acetabular Injuries
  • Gynecological conditions and treatments
  • Clinical practice guidelines implementation
  • Ovarian function and disorders
  • Vascular Tumors and Angiosarcomas
  • Intestinal and Peritoneal Adhesions

University of Lausanne
2017-2024

University Hospital of Lausanne
2015-2024

Munich University of Applied Sciences
2024

University of Fribourg
2023

Fribourg Development Agency
2023

Check Point (Israel)
2023

Hôpital Orthopédique de la Suisse Romande
2018-2019

Hôpital de l'enfance
2018-2019

BackgroundEnhanced Recovery After Surgery Society publishes guidelines on perioperative care, but these should be validated prospectively.ObjectiveTo evaluate the association between compliance with Enhanced Gynecologic/Oncology guideline elements and postoperative outcomes in an international cohort.Study DesignThe study comprised 2101 patients undergoing elective gynecologic/oncology surgery January 2011 November 2017 10 hospitals across Canada, United States, Europe. Patient demographics,...

10.1016/j.ajog.2019.04.028 article EN cc-by-nc-nd American Journal of Obstetrics and Gynecology 2019-04-30

Adequate selection of patients with peritoneal metastasis (PM) for cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) remains critical successful long-term outcomes. Factors reflecting tumor biology are currently poorly represented in the process. The prognostic relevance RAS/RAF mutations PM unclear.Survival data colorectal operated 6 European tertiary centers were retrospectively collected predictive factors survival identified by Cox regression analyses. A...

10.1097/sla.0000000000002899 article EN Annals of Surgery 2018-10-10

Enhanced recovery after surgery (ERAS) programs has shown clinical benefits in gynecologic surgery. The aim of the present study was to compare costs before and implementation an ERAS program for surgery.Retrospective comparing perioperative between consecutive patient groups undergoing (benign, staging or debulking) (I, 2012-13) prior, (II) immediately after, (III, 2014-16) three years implementation. Preoperative, intraoperative, postoperative real were collected each via hospital...

10.1016/j.ygyno.2019.06.004 article EN cc-by-nc-nd Gynecologic Oncology 2019-06-13

Abstract Background Multimodal treatment, including systemic treatment and surgery, improved the prognosis of peritoneal metastasis (PM). Despite all efforts, recurrence rates remain high, little data are available about clinical behavior or molecular patterns PM in comparison to hematogenous metastasis. Here, we aimed analyze after multimodal for from colorectal cancer. Methods Patients with undergoing chemotherapy cytoreductive surgery plus hyperthermic intraperitoneal (CRS/HIPEC) between...

10.1093/jnci/djab001 article EN JNCI Journal of the National Cancer Institute 2021-01-15

Little is known on the prevalence of multimorbidity (MM) in general population. We aimed to assess MM using measured or self-reported data Swiss Cross-sectional, population-based study conducted between 2003 and 2006 city Lausanne, Switzerland, including 3714 participants (1967 women) aged 35 75 years. Clinical evaluation was by thoroughly trained nurses medical assistants psychiatric psychologists psychiatrists. For conditions, two definitions were used: either based participant's...

10.1186/s12889-015-1515-x article EN cc-by BMC Public Health 2015-02-18

<h3>Introduction</h3> Enhanced recovery after surgery (ERAS) guidelines in gynecologic are a set of multiple recommendations based on the best available evidence. However, according to previous studies, maintaining high compliance is challenging daily clinical practice. The aim this study was assess impact individual ERAS items outcomes. <h3>Methods</h3> Retrospective cohort prospectively maintained database 446 consecutive women undergoing oncology (both open and minimally invasive) within...

10.1136/ijgc-2019-000268 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2019-03-21

Importance Enhanced Recovery After Surgery (ERAS) guidelines and the World Health Organization Surgical Safety Checklist (SSC) are 2 well-established tools for optimizing patient outcomes perioperatively. Objective To integrate to facilitate key perioperative decision-making. Evidence Review Snowball sampling recruited international ERAS users from multiple clinical specialties. A 3-round modified Delphi consensus model was used evaluate 27 colorectal or gynecologic oncology recommendations...

10.1001/jamanetworkopen.2022.48460 article EN cc-by-nc-nd JAMA Network Open 2023-02-08

Background: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is a novel mode of intraperitoneal (IP) drug delivery claiming high IP tissue concentrations with low systemic uptake. The aim was to study inflammatory response and toxicity after PIPAC. Methods: Retrospective monocentric analysis consecutive cohort PIPAC patients between January 2015 April 2016. Detailed hematological biochemical performed the day before surgery once daily until discharge. Comparative statistics were...

10.7150/jca.21460 article EN cc-by-nc Journal of Cancer 2017-11-28

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Mobilization after surgery is recommended to reduce the risk of adverse effects and improve recovery. The aim this study was examine associations between perioperative physical activity postoperative outcomes in colorectal surgery. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; daily number footsteps recorded from preoperative day 5 3 a prospective cohort patients using wrist accelerometers. Timed Up Go Test (TUGT), 6 Min Walking (6MWT), peak...

10.1159/000507578 article EN cc-by-nc-nd European Surgical Research 2020-01-01

Abstract Objectives To assess the interobserver reliability (IOR) of Tile classification system, and its potential influence on outcomes, for interpretation CT images pelvic fractures by radiologists surgeons. Methods Retrospective data (1/2008–12/2016) from 238 patients with were analyzed. Mean patient age was 44 years (SD 20); 66% male. There 54 A, 82 B, 102 C type injuries. The 30-day mortality rate 15% (36/238). Six observers, three radiologists, surgeons different levels experience...

10.1007/s00330-020-07247-0 article EN cc-by European Radiology 2020-09-08

In early-stage cervical cancer, lymph node status is of paramount importance to determine the best therapeutic strategy and one most important prognostic factors survival. According main international guidelines, pelvic full lymphadenectomy recommended for staging. Sentinel (SLN) biopsy an accurate method assessment nodal involvement has been suggested instead systematic dissection (PLND). The SLN technique requires a learning-curve be well performed. Combined detection with technetium-99...

10.21037/cco-21-5 article EN Chinese Clinical Oncology 2021-04-01

Abstract Aim The present study aimed to analyse fluid management and define optimal fluid‐related thresholds for elective open colorectal surgery. Method A retrospective analysis was made of all consecutive resections performed in our tertiary centre between May 2011 2017. main outcomes were postoperative complications [overall (I–V) severe ( IIIB –V) according the Clavien classification], respiratory ileus POI ). Critical regarding perioperative weight gain identified by using receiver...

10.1111/codi.14465 article EN Colorectal Disease 2018-11-08

Summary Introduction Nurses are the linchpin of any Enhanced Recovery After Surgery (ERAS) program, as they in direct contact with patients and various caregivers. The aim present survey was to assess ERAS key factors challenges from a nurse’s perspective. Methods A qualitative study among dedicated nurses Interactive Audit System (EIAS) administrators using an online questionnaire (Survey Monkey®, Palo Alto, CA, United States) comprising 29 questions. focused on drawbacks encountered during...

10.1007/s10353-021-00698-9 article EN cc-by European surgery. Supplement/European surgery 2021-03-17

To assess the feasibility of a prehabilitation program and its effects on physical performance outcomes after major abdominal surgery.In this prospective pilot study, patients underwent involving three training sessions per week for 3 weeks preoperatively. The delivering intervention was assessed based recruitment adherence to program. Its impacts fitness (oxygen uptake (VO2)) (Timed Up Go Test, 6-Minute Walk Test) were evaluated.From May 2017 January 2020, 980 identified 44 (4.5%) invited...

10.1177/03000605211060196 article EN cc-by-nc Journal of International Medical Research 2021-11-01
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