- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Nutrition and Health in Aging
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Airway Management and Intubation Techniques
- Sleep and Work-Related Fatigue
- Pleural and Pulmonary Diseases
- Congenital Diaphragmatic Hernia Studies
- Pneumonia and Respiratory Infections
- Microbial infections and disease research
- Fungal Infections and Studies
- Sleep and related disorders
- Electrolyte and hormonal disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Parasites and Host Interactions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Research and Treatments
- Healthcare Decision-Making and Restraints
- Tuberculosis Research and Epidemiology
- Sarcoma Diagnosis and Treatment
- Peripheral Nerve Disorders
- Clinical Nutrition and Gastroenterology
Philippine General Hospital
2007-2025
University of the Philippines Manila
2018-2024
Murayama Medical Center
2019
Cardiovascular disease is a common comorbidity in chronic obstructive pulmonary (COPD). Yet cardiovascular and risk under diagnosed COPD often undertreated, increasing the of cardiopulmonary events. We formed Global Working Group experts to produce consensus statement detailing identification management patients with COPD. conducted virtual meetings supplemented by remote working communication. The Chairs (CPG, MB) proposed draft statement, which was further developed Group. selection final...
Background and objectives: The loss of muscle or fat free mass (FFM) as a result systemic inflammation poor nutrition in Chronic Obstructive Pulmonary Disease (COPD), is recognized an important factor that influences symptoms disease-related outcomes. To date, there are no data on body composition among Filipino COPD patients how it impacts disease severity. This paper examined the relationship Fat Free Mass Index (FFMI = FFM/height) sarcopenia with severity variables. Methods: was...
Purpose This study was performed to determine the clinical biomarkers and cytokines that may be associated with disease progression in-hospital mortality in a cohort of hospitalized patients RT-PCR confirmed moderate severe COVID-19 infection from October 2020 September 2021, during first wave pandemic before advent vaccination. Patients methods Clinical profile obtained medical records. Laboratory parameters (complete blood count [CBC], albumin, LDH, CRP, ferritin, D-dimer, procalcitonin)...
Background. Severe and critical COVID-19 disease is characterized by hyperinflammation involving pro-inflammatory cytokines, particularly IL-6. Tocilizumab a monoclonal antibody that blocks IL-6 receptors.Objectives. This study evaluated the efficacy of tocilizumab in Filipino patients with severe to disease. Methods. phase 3 randomized double-blind trial, included hospitalized for or 1:1 ratio receive either plus local standard care placebo care. Patients were eligible repeat IV...
The global pandemic caused by the coronavirus disease 2019 (COVID-19) resulted in many deaths from fulminant respiratory failure. Chronic obstructive pulmonary (COPD) is leading cause of morbidity and mortality worldwide. There has been great concern regarding impact COPD on COVID-19 illness.Data Philippine CORONA study were analyzed to determine association terms mortality, severity, failure, mechanical ventilation, lengths stay intensive care unit (ICU) hospital.A total 10,881 patients...
Background. The prone position has been seen to benefit patients experiencing acute respiratory distress syndrome. However, performing this in pregnant difficult and raises safety concerns. Objective. current study aimed test the use of a supportive pillow (Prone Pillow for Pregnant Patients or 4P) address concerns regarding position. Methods. prospectively evaluated patient comfort usability among healthcare workers with qualitative quantitative measures. Results. A total three were...
BackgroundAppropriate nutritional support is a key component of care for critically ill patients. While malnutrition increases complications, impacting long term outcomes and healthcare-related costs, uncertainties persist regarding optimal provision in this setting.MethodsAn international group healthcare providers (HCPs) from critical specialties nutrition researchers convened to identify knowledge gaps learnings studies nutrition. Clinical research needs were identified order better...
Objectives. The highly polymorphic nature of the CYP2D6 gene and its central role in metabolism commonly used drugs make it an ideal candidate for pharmacogenetic screening. This study aims to determine prevalence polymorphisms among Filipinos their association lung cancer. Method. Forty seven single nucleotide (SNPs) were genotyped from DNA samples 115 cases with cancer age- sex-matched controls. Results. Results show that 18 out 47 have significant genotypic variability (>1% at least 2...
Conclusion: Pulmonary agenesis commonly affects the left side with male predominance and very few cases involving right upper lobe were reported in literature.We encountered such a rare case elderly pulmonary varix of lobe.