A5020832846- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Healthcare Policy and Management
- Cardiomyopathy and Myosin Studies
- Cardiac Arrest and Resuscitation
- Primary Care and Health Outcomes
- Venous Thromboembolism Diagnosis and Management
- Healthcare cost, quality, practices
- Cardiac electrophysiology and arrhythmias
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Chronic Disease Management Strategies
- Cardiac Structural Anomalies and Repair
The University of Queensland
2020-2024
Prince Charles Hospital
2007-2024
Prince Charles Hospital
2021-2022
Royal Brisbane and Women's Hospital
2022
Holy Spirit Northside Private Hospital
2021
St George’s University Hospitals NHS Foundation Trust
2021
Queen Elizabeth Hospital
2015-2020
The University of Adelaide
2015-2020
Basil Hetzel Institute
2017-2020
Central Adelaide Local Health Network
2017-2020
Objectives: To characterise management of suspected acute coronary syndrome (ACS) in Australia and New Zealand, to assess the application recommended therapies according published guidelines. Design, setting patients: All patients hospitalised with or confirmed ACS between 14 27 May 2012 were enrolled from participating sites which identified through public records health networks. Descriptive logistic regression analysis was performed. Main outcome measures: Rates guideline-recommended...
<h3>Objective</h3> To evaluate the proportion of patients hospitalised with acute coronary syndrome (ACS) in Australia and New Zealand who received optimal inpatient preventive care to identify factors associated care. <h3>Methods</h3> All bi-nationally ACS were identified between 14–27 May 2012. Optimal in-hospital was defined as having lifestyle advice, referral rehabilitation, prescription secondary prevention pharmacotherapies. Multilevel multivariable logistic regression used determine...
Background: High-sensitivity cardiac troponin (hs-cTn) laboratory assays are used to rule out myocardial infarction (MI) on presentation, but prolonged result turnaround times can delay patient management. Our primary aim was identify patients at low risk of index MI using a rapid point-of-care (POC) whole-blood hs-cTnI assay presentation with potential early discharge. Methods: Consecutive presenting the emergency department from 2 prospective observational studies suspected acute coronary...
Abstract Aims Contemporary long‐term survival following a heart failure (HF) hospitalization is uncertain. We evaluated up to 10 years after HF using national data from Australia and New Zealand, identified predictors of survival, estimated the attributable loss in life expectancy. Methods results Patients hospitalized with primary diagnosis 2008–2017 were all‐cause mortality assessed by linking Death Registries. Flexible parametric models used estimate A total 283 048 patients included...
Background: Data on long-term outcomes following an acute stroke are sparse. We assessed survival, risk of recurrent and loss in life expectancy using population-wide data from Australia New Zealand. Methods: included all adults with the first hospitalization during 2008 2017 at public most private hospitals. Patients were followed up to 10 years after by linkage each region’s Registry Deaths subsequent hospitalizations. Flexible parametric survival modeling was used estimate all-cause...
Abstract Background and Aims Strategies to assess patients with suspected acute myocardial infarction (AMI) using a point-of-care (POC) high-sensitivity cardiac troponin I (hs-cTnI) assay may expedite emergency care. A 2-h POC hs-cTnI strategy for AMI was derived validated. Methods In two international, multi-centre, prospective, observational studies of adult (1486 derivation cohort 1796 validation cohort) AMI, (Siemens Atellica® VTLi) measured at admission 2 h later. Adjudicated final...
Patients aged ≥ 65 years are vulnerable to readmissions due a transient period of generalized risk after hospitalization. However, whether young and middle-aged adults share similar pattern is uncertain. We compared the rate, timing, readmission diagnoses following hospitalization for heart failure (HF), acute myocardial infarction (AMI), pneumonia among patients 18-64 with years.We used an all-payer administrative dataset from California consisting all hospitalizations HF (n=206,141), AMI...
Young women (<65 years) experience a 2- to 3-fold greater mortality risk than younger men after an acute myocardial infarction. However, it is unknown whether they are at higher for 30-day readmission, and if this association varies by age. We examined sex differences in the rate, timing, principal diagnoses of readmissions, including independent effect following adjustment confounders.We included patients aged 18 64 years with diagnosis Data were used from Healthcare Cost Utilization...
Abstract Background In suspected myocardial infarction (MI), guidelines recommend using high-sensitivity cardiac troponin (hs-cTn)-based approaches. These require fixed assay-specific thresholds and timepoints, without directly integrating clinical information. Using machine-learning techniques including hs-cTn routine variables, we aimed to build a digital tool estimate the individual probability of MI, allowing for numerous assays. Methods 2,575 patients presenting emergency department...
Background— Organizational and wider health system factors influence the implementation success of interventions. Clinical Pathways in Acute Coronary Syndromes 2 is a cluster randomized trial clinical pathway–based intervention to improve acute coronary syndrome care hospitals China. We performed qualitative evaluation examine system-level barriers implementing pathways dynamic healthcare environment Methods Results— A descriptive analysis 40 in-depth interviews with professionals conducted...
Recent US studies report rising rates of mortality and in-hospital complications following catheter ablation atrial fibrillation (AF), but whether this is a global phenomenon uncertain. The aim study was to examine trends in 30-day AF Australia New Zealand (ANZ) from 2008 2017.We identified 37 243 (mean age 62.4 ± 11.5 years, 29.6% females, 94.5% elective procedures) ablations using national hospitalization data. primary outcome occurrence any complication, including all-cause mortality,...
Background- Substantial evidence-practice gaps exist in the management of acute coronary syndromes (ACS) China. Clinical pathways are tools for improving ACS quality care but have not been rigorously evaluated. Methods and Results- Between October 2007 August 2010, a improvement program was conducted 75 hospitals throughout China with mixed methods evaluation cluster randomized, controlled trial. Eligible were level 2 or 3 centers routinely admitting >100 patients per year. Hospitals...
Background: Long-term nonfatal outcomes after implantable cardioverter-defibrillator (ICD) placement are poorly defined. Objective: To determine the long-term risk for ICD-related complications requiring reoperation or hospitalization and reasons other than complications, to assess associated patient device characteristics. Design: Observational cohort study of ICD implantations from National Cardiovascular Data Registry registry linked with Medicare fee-for-service claims data. Setting:...
There are no contemporary national-level data on Emergency Medical Services (EMS) response times for suspected stroke in the United States (US). Because effective treatment is time-dependent, we characterized stroke, and examined whether they met guideline recommendations.Using National EMS Information System dataset, included 911 calls patients ≥ 18 years with an provider impression of stroke. We variation total time by dispatch notification age, sex, race, region, day, day week, as well...
Background To date, limited population‐level studies have examined the impact of sex on acute complications cardiac implantable electronic devices ( CIED) , including permanent pacemakers, cardioverter defibrillators, and resynchronization therapy devices. Methods Results We studied all patients aged >18 years from 2010 to 2015 who were a resident Australia or New Zealand, undergoing new pacemaker, defibrillator implant. Standardized variables collected patient demographic...
Cardiovascular implantable electronic devices (CIEDs) are associated with procedure-related complications, yet little is known about variation in complication rates among institutions that may suggest disparities care quality.To assess institutional risk-standardized (RSCRs) for CIED.Cohort study.174 hospitals Australia and New Zealand, 98 of which implanted at least 25 CIEDs during the study period.81 304 patients older than 18 years (mean, 74.7 [SD, 12.4]; 37.9% female) who received a new...
Objective To assess long term survival and patient characteristics associated with following acute myocardial infarction (AMI) in Australia New Zealand. Design Cohort study. Setting, participants All patients admitted AMI (ICD-10-AM codes I21.0‒I21.4) to all public most private hospitals Zealand during 2009‒2015. Main outcome measure All-cause mortality up seven years after an AMI. Results 239 402 initial admissions were identified; the mean age of was 69.3 (SD, 14.3 years), 154 287 men...