- Thermoregulation and physiological responses
- Neurofibromatosis and Schwannoma Cases
- Exercise and Physiological Responses
- Sports Performance and Training
- Muscle metabolism and nutrition
- Meningioma and schwannoma management
- Infrared Thermography in Medicine
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Adipose Tissue and Metabolism
- Electromagnetic Fields and Biological Effects
- Academic Research in Diverse Fields
- Neuroendocrine Tumor Research Advances
- Business and Management Studies
- Wireless Body Area Networks
- Sarcoma Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Bone Tumor Diagnosis and Treatments
- Climate Change and Health Impacts
- Physical Education and Sports Studies
- Spaceflight effects on biology
- Science and Science Education
- Genetics and Physical Performance
- Soft tissue tumors and treatment
Universidade Federal de Minas Gerais
2011-2022
Universidade Federal de Alagoas
2022
Universidade de São Paulo
2022
National Institute for Space Research
2022
University of Waterloo
2022
Durham University
2022
Tampere University
2022
Children's Hospital of Los Angeles
2021
Hospital das Clínicas da Universidade Federal de Minas Gerais
2014-2018
Federal Center for Technological Education of Minas Gerais
2011
PurposeBy incorporating major developments in genetics, ophthalmology, dermatology, and neuroimaging, to revise the diagnostic criteria for neurofibromatosis type 1 (NF1) establish Legius syndrome (LGSS).MethodsWe used a multistep process, beginning with Delphi method involving global experts subsequently non-NF experts, patients, foundations/patient advocacy groups.ResultsWe reached consensus on minimal clinical genetic diagnosing differentiating NF1 LGSS, which have phenotypic overlap...
Neurofibromatosis type 2 (NF2) and schwannomatosis (SWN) are genetically distinct tumor predisposition syndromes with overlapping phenotypes. We sought to update the diagnostic criteria for NF2 SWN by incorporating recent advances in genetics, ophthalmology, neuropathology, neuroimaging.We used a multistep process, beginning Delphi method involving global disease experts subsequently non-neurofibromatosis clinical experts, patients, foundations/patient advocacy groups.We reached consensus on...
In order to verify the effects of heat and exercise acclimation (HA) on resting exercise-induced expression plasma leukocyte shock protein 72 (Hsp72) in humans, nine healthy young male volunteers (25.0 ± 0.7 years; 80.5 2.0 kg; 180 2 cm, mean SE) exercised for 60 min a hot, dry environment (40 0°C 45 0% relative humidity) 11 days. The protocol consisted running treadmill using controlled hyperthermia technique which work rate was adjusted elevate rectal temperature by 1°C 30 maintain it...
Neurofibromatoses (NF) are a group of genetic multiple tumor growing predisposition diseases: neurofibromatosis type 1 (NF1), 2 (NF2) and schwannomatosis (SCH), which have in common the neural origin tumors cutaneous signs. They affect nearly 80 thousand Brazilians. In recent years, increased scientific knowledge on NF has allowed better clinical management reduced complication morbidity, resulting higher quality life for patients. most cases, neurology, psychiatry, dermatology, geneticists,...
O objetivo deste trabalho é fazer uma revisão sobre a hidratação e discutir se, durante o exercício, reposição de líquidos acordo com sede suficiente para hidratar indivíduo. A perda hídrica pela sudorese induzida pelo especialmente realizado em ambientes quentes, pode levar à desidratação, alterar equilíbrio hidroeletrolítico, dificultar termorregulação e, assim, representar um risco saúde e/ou provocar diminuição no desempenho esportivo. Tem sido citado que os atletas não ingerem...
We investigated brain mechanisms modulating fatigue during prolonged physical exercise in cold environments. In a first set of studies, each rat was subjected to three running trials different ambient temperatures ( T ). At 8 °C and 15 °C, core body temperature ) decreased increased, respectively, whereas at 12 the did not change throughout exercise. another experiments, rats were randomly assigned receive bilateral 0.2 μL injections 2.5 × 10 −2 M methylatropine or 0.15 NaCl solution into...
There is evidence that brain temperature (T brain) provides a more sensitive index than other core body temperatures in determining physical performance. However, no study has addressed whether the association between performance and increases T temperate environment dependent upon exercise intensity, this was primary aim of present study. Adult male Wistar rats were subjected to constant at three different speeds (18, 21, 24 m/min) until onset volitional fatigue. continuously measured by...
Centrally stimulated sweat rate produced by graded exercise until exhaustion was compared to the local induced pilocarpine, often used as a sweating index for healthy individuals. Nine young male volunteers (22 ± 4 years) were studied in temperate environment two situations: at rest and during progressive with 25 W increases every 2 min exhaustion, on cycle ergometer. In both situations, right forearm 5 ml 0.5% pilocarpine hydrochloride applied iontophoresis (1.5 mA, min), left control....
OBJETIVO: Determinar a prevalência das características clínicas da neurofibromatose tipo 1 (NF1), avaliar sua gravidade e visibilidade quantificar baixa estatura, macrocrania, força muscular as alterações motricidade oral voz nesta enfermidade. MÉTODOS: 183 pacientes atendidos no Centro de Referência em Neurofibromatose Minas Gerais (CRNF-MG) foram avaliados quanto à frequência manifestações complicações NF1. A avaliadas com o uso escalas Riccardi Ablon respectivamente. As verificadas do...
What is the central question of this study? Clinical studies suggest that obesity 'protects' against osteoporosis. However, these used only bone densitometry and assessed one site, which insufficient to enable conclusions be drawn about response whole skeleton. Furthermore, effects exercise on responses in have not been explored previously. main finding what its importance? We show causes osteopetrosis. Therefore, classical perspective 'protective obesity' needs reviewed, an important tool...
Programming online judges (POJs) have been increasingly used in CS1 classes, as they allow students to practice and get quick feedback. For instructors, it is a useful tool for creating assignments exams. However, selecting problems POJs time consuming. First, are generally not organized based on topics covered the syllabus. Second, assessing whether require similar effort be completed map onto same topic subjective expert-dependent task. The difficulty increases if instructor must create...
The present study evaluated whether the luteal phase elevation of body temperature would be offset during exercise by increased sweating, when women are normally hydrated. Eleven performed 60 min cycling at 60% their maximal work load 32ºC and 80% relative air humidity. Each subject participated in two identical experimental sessions: one follicular (between days 5 8) other 22 25). Women with serum progesterone >3 ng/mL, were classified as group 1 (N = 4), whereas others 2 7). Post-exercise...
Objects To compare insulin resistance (IR) and metabolic aspects of patients with neurofibromatosis type 1 (NF1) individuals without the disease. Subjects methods Forty NF1 were matched by sex, age, body mass index (BMI) to 40 controls from community. Blood samples collected for biochemical assessment. Homeostasis model assessment adiponectin (HOMA-AD), (HOMA-IR), adiponectin/leptin ratio (ALR) used identify IR. Results The median HOMA-IR values similar between groups. However, HOMA-AD value...
Studies indicate a lower occurrence of diabetes mellitus (DM) in patients with neurofibromatosis type 1 (NF1). Fasting blood glucose (FBG) level is the main criterion used to diagnose DM and intolerance. Therefore, this study compared FBG between adults NF1 non-NF1 controls. We selected clinical records 57 out 701 individuals attending Neurofibromatosis Outpatient Reference Center Clinics Hospital Federal University Minas Gerais Brazil. The were matched controls from Brazilian Longitudinal...
Thermal environmental stress can anticipate acute fatigue during exercise at a fixed intensity (%VO2max). Controversy exists about whether this anticipation is caused by the absolute internal temperature (Tint, ºC), heat storage rate (HSR, cal/min) or both mechanisms. The aim of present study was to (total time, TET) thermal determining Tint and HSR from abdominal temperature. controlled in an chamber determined as wet bulb globe (ºC), with three temperatures being studied: cold (18ºC),...
The present study investigated whether the effects of central cholinergic stimulation on thermoregulation during exercise are modulated by arterial baroreceptors. Wistar rats were submitted to sinoaortic denervation (SAD) or sham (SHAM) and then fitted with a chronic guide cannula into lateral cerebral ventricle. After 2 weeks, catheter was implanted ascending aorta, temperature sensor peritoneal cavity. Two days later, treadmill at 18 m/min until fatigued. Thermoregulatory cardiovascular...