A5100392175- Renal and Vascular Pathologies
- Renal Diseases and Glomerulopathies
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Renal Transplantation Outcomes and Treatments
- Complement system in diseases
- Diabetes Management and Research
- Chronic Kidney Disease and Diabetes
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diet, Metabolism, and Disease
- Organ Donation and Transplantation
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Radiomics and Machine Learning in Medical Imaging
- Acute Kidney Injury Research
- Acute Ischemic Stroke Management
- Respiratory Support and Mechanisms
- Immunodeficiency and Autoimmune Disorders
- Electrolyte and hormonal disorders
- Gastric Cancer Management and Outcomes
- Blood groups and transfusion
- Hemoglobinopathies and Related Disorders
- Neurological Complications and Syndromes
Shanghai Tenth People's Hospital
2022-2025
Shandong Academy of Chinese Medicine
2025
Qingdao University
2023-2025
Qingdao Municipal Hospital
2025
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Jiangxi Provincial People's Hospital
2023-2025
Hebei Medical University
2021-2025
First Affiliated Hospital of Jiangxi Medical College
2023-2025
Tongji University
2019-2024
Oxidative stress has been implicated in the pathogenesis and progression of dyslipidemia. We aimed to investigate association between oxidative balance score, dyslipidemia, as well assess mortality risk associated with score patients
Background Currently, there is a dearth of systematic research data on the phenomenon false-positive reactions in treponemal tests. The aim this study to analyze clinical characteristics and influencing factors associated with tests patients, so as enhance diagnostic accuracy syphilis mitigate misdiagnosis-induced incorrect treatment.
Scope Hypothalamic astrogliosis and inflammation cause neural injury, playing a critical role in metabolic syndrome development. This study investigated whether how fructose caused hypothalamic vivo vitro. The inhibitory effects of betaine on astrogliosis, were explored to address its improvement fructose‐induced syndrome. Methods results Rats or astrocytes exposed then treated with betaine. Neural proinflammatory markers, Toll‐like receptor 4/nuclear factor‐κB (TLR4/NF‐κB) pathway, histone...
Background and objectives Recent developments indicated that functional magnetic resonance imaging (MRI) could potentially provide noninvasive assessment of kidney interstitial fibrosis in patients with diseases, but direct evidence from histopathology is scarce. We aimed to explore the diagnostic utilities MRI for evaluation allograft fibrosis. Design, setting, participants, & measurements prospectively examined 103 transplant recipients who underwent for-cause biopsies 20 biopsy-proven...
This study compares the clinical efficacy and outcomes of three surgical techniques-robot-assisted stereotactic assistance (ROSA), neuroendoscopy, craniotomy-in removal intracranial hematomas in patients with cerebral hemorrhage affecting basal ganglia. retrospective included 110 patients, who were grouped based on method used: 40 ROSA group, 50 craniotomy 20 endoscopy group. We then compared group those groups. Compared had a significantly shorter operation time, higher hematoma clearance...
Abstract Background The aim of the present cross-sectional study was to assess possible associations between osteopontin (OPN), and thrombin-cleaved (N-half) OPN, nephropathy coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM). Methods Plasma levels N-half high-sensitivity C-reactive protein (hsCRP) were determined 301 diabetic (n = 226) or without 75) angiographically documented CAD (luminal diameter narrowing >50%), as well 75 non-diabetic controls normal...
Fructose consumption can induce insulin resistance and metabolic syndrome, which are associated with glomerular podocyte dysfunction proteinuria. This study investigated whether fructose caused signaling impairment in injury, curcumin reduced these disturbances.Rats were fed 10% for 6 weeks then orally cotreated next weeks. Metabolic microRNA expression, evaluated. Curcumin significantly alleviated fructose-induced injury proteinuria, miR-206 low-expression, protein tyrosine phosphatase 1B...
Purpose: Corneal neovascularization (CNV) impairs corneal transparency and visual acuity. The study aims to deepen our understanding of the molecules involved in CNV induced by alkali burns, facilitate a better grasp mechanisms, uncover potential therapeutic targets. Methods: Eighty-four mice were selected for establishing models via burns. On days 3, 7, 14 after observations histological investigations conducted. An integrated analysis RNA sequencing (RNA-seq)-based transcriptomics...
Fructose-induced hyperinsulinemia is associated with insulin compensative secretion and predicts the onset of type 2 diabetes. In this study, we investigated preservation dietary flavonoid quercetin on pancreatic β -cell mass function in fructose-treated rats INS-1 -cells. Quercetin was confirmed to reduce serum leptin levels blockade islet hyperplasia fructose-fed rats. It also prevented fructose-induced proliferation hypersecretion High fructose increased forkhead box protein O1 (FoxO1)...
Background Oxidative stress has been implicated in the pathogenesis of hearing loss (HL). Dietary intake is a modifiable factor that could influence oxidant and antioxidant capacity. We hypothesized higher composite dietary index (CDAI) associated with reduced odds for HL. Methods Adult participants from 2001–2012 & 2015–2018 National Health Nutrition Examination Study were included this cross-sectional study. The CDAI was calculated vitamins A, C, E, selenium, zinc, caretenoid through...
Immunosuppression has been described as a consequence of brain injury and infection by different mechanisms. Angiostrongylus cantonensis can cause to the central nervous system eosinophilic meningitis human. Both T cell B immunity play an essential role in resistance infection. However, whether caused A. lead immunosuppression is not clear. Therefore, present study sought observe alteration immune responses mice infected with cantonensis. Mice were 20 third-stage larvae. The messenger RNA...
Abstract Objective To evaluate the added benefit of diffusion-weighted imaging (DWI) over clinical parameters in predicting kidney allograft function decline. Methods Data from 97 patients with DWI were retrospectively analyzed. The signals analyzed both mono-exponential and bi-exponential models, yielding total apparent diffusion coefficient (ADC T ), true (D), pseudo-diffusion (D*), perfusion fraction (fp). Three predictive models constructed: Model 1 parameters, 2 3 parameters. capability...
Abstract Purpose: Increasing the central dose for large, locally advanced, drug-resistant gastrointestinal stromal tumors (LADR-GIST) has consistently been a significant challenge. This study aims to evaluate feasibility of using stereotactic ablation radiotherapy enhance radiation delivered center large LADR-GISTs.
Methods and Materials: involved five patients with LADR-GIST who were treated CyberKnife. The gross tumor volume (GTV) was delineated as multi-shell structure. Five...
This study aims to investigate the effect of β2-microgolobulin (β2-MG) on occurrence cardiovascular events (CVE) in hemodialysis patients and its relationship with prognosis. In this retrospective study, we included 102 treated at Jinan People's Hospital Affiliated Shandong First Medical University from September 2020 January 2023. Clinical follow-up data were collected. Logistic regression was used evaluate between β2-MG CVEs, while Cox proportional hazards analysis assess possible...
Objectives Onconephrology is an expanding subspecialty focused on the management of cancer patients with renal injury. This study used a comprehensive bibliometric analysis to emphasize need for cooperation between oncologists and nephrologists, exploring current trends future research areas in onconephrology.
Objective Prediabetes is a chronic condition characterized by elevated blood glucose levels that are not yet high enough to be classified as diabetes. It particularly prevalent among middle-aged and elderly populations. This study aims investigate the association between novel marker of insulin resistance-the estimated disposal rate (eGDR)-and reversion prediabetes normoglycaemia or progression diabetes in Chinese population. Methods prospective cohort utilized baseline data from 2011 China...