About
Contact & Profiles
A5071854572
Research Areas
- Estrogen and related hormone effects
- Prostate Cancer Treatment and Research
- Cytokine Signaling Pathways and Interactions
Nankai University
2022
Abstract Background Resistance to androgen deprivation therapy remains a major challenge for the clinical treatment of patients with castration-resistant prostate cancer (CRPC). CYP1B1, critical enzyme that catalyzes conversion estradiol 4-Hydroxy-17β-estradiol (4-OHE2), has been reported promote development and progression hormone-related cancer, but its role in CRPC is unclear. Methods To explore underlying mechanism which CYP1B1 promotes stem cells (PCSCs) characteristics, bioinformatics...
10.1186/s12964-021-00807-x
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Cell Communication and Signaling
2022-03-15
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