A5023051149- Liver Disease Diagnosis and Treatment
- Food Quality and Safety Studies
- Fungal Biology and Applications
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Phytochemicals and Antioxidant Activities
- Bamboo properties and applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Dyeing and Modifying Textile Fibers
- Pharmacological Effects of Natural Compounds
- Protein Hydrolysis and Bioactive Peptides
- Algal biology and biofuel production
- Phytochemistry and Bioactivity Studies
- Medical Research and Treatments
- Fermentation and Sensory Analysis
- Polysaccharides and Plant Cell Walls
- Cultural and Historical Studies
- Enzyme-mediated dye degradation
- Diatoms and Algae Research
- Liver physiology and pathology
- Innovative Human-Technology Interaction
- Microbial Metabolites in Food Biotechnology
- Water Quality Monitoring and Analysis
- Lung Cancer Treatments and Mutations
- Dye analysis and toxicity
Seoul National University
2022-2025
National Cancer Center
2024-2025
Pohang University of Science and Technology
2025
Seoul National University Hospital
2023-2025
Korea University
2010-2014
Chosun University
2013
No medication has been found to reduce liver-related events. We evaluated the effect of sodium-glucose cotransporter-2 inhibitor (SGLT2i) on outcomes.
Abstract Background and Aims Metabolic dysfunction‐associated fatty liver disease (MAFLD) encompasses heterogeneous diseases associated with metabolic disorders. We aimed to evaluate the association between MAFLD extrahepatic malignancies based on subtypes. Methods This nationwide cohort study included 9 298 497 patients who participated in a health‐screening programme of National Health Insurance Service Korea 2009. Patients were further classified into four subgroups: non‐MAFLD, diabetes...
Background/Aim: Atezolizumab plus bevacizumab and lenvatinib are currently available as first-line therapy for the treatment of unresectable hepatocellular carcinoma (HCC). However, comparative efficacy studies still limited. This study aimed to investigate effectiveness these treatments in HCC patients with portal vein tumor thrombosis (PVTT).Methods: We retrospectively included who received either atezolizumab or systemic PVTT. Primary endpoint was overall survival (OS), secondary...
518 Background: Notwithstanding the pressing need for adjuvant therapy hepatocellular carcinoma (HCC), most therapies, including atezolizumab/bevacizumab, have failed. Meanwhile, immunotherapy utilizing autologous cytokine-induced killer (CIK) cells HCC improved recurrence-free survival (RFS) in a previously reported randomized controlled trial (RCT) and real-world data. This study aimed to assess longer-term outcomes of RCT elucidate underlying mechanisms sustained effects CIK cell...
Background/AimsHepatocellular carcinoma (HCC) is the sixth most common cancer and second leading cause of cancer-related deaths in South Korea. This study evaluated characteristics Korean patients newly diagnosed with HCC 2016–2018. MethodsData from Primary Liver Cancer Registry (KPLCR), a representative database Korea, were analyzed. investigated 4,462 registered KPLCR ResultsThe median patient age was 63 (interquartile range, 55–72) years; 79.7% male. Hepatitis B infection underlying liver...
Chronic hepatitis B (CHB) is related to an increased risk of extrahepatic malignancy (EHM), and antiviral treatment associated with incidence EHM comparable controls. We compared the risks intrahepatic (IHM) between entecavir (ETV) tenofovir disoproxil fumarate (TDF) treatment. Using data from National Health Insurance Service Korea, this nationwide cohort study included treatment-naïve CHB patients who initiated ETV (n=24,287) or TDF (n=29,199) therapy 2012 2014. The primary outcome was...
Abstract: This study aimed to develop an oral delivery system using clay-based organic–inorganic hybrid materials improve the bioavailability of drug, flurbiprofen, which is poorly soluble in water. 3-aminopropyl functionalized magnesium phyllosilicate (AMP clay) was synthesized by a one-pot direct sol-gel method, and then flurbiprofen (FB) incorporated into AMP clay (FB-AMP) at different drug/clay ratios. The structural characteristics FB-AMP formulation were confirmed X-ray diffraction,...
ABSTRACT Crab shell particles (Protunus trituberculatus) and activated carbon (Norit 0,8 SUPRA) were used as packing materials in a fixed-bed column. When 1 g crab was added column packed with 10 carbon, breakthrough occurred at 1500 bed volumes compared to 380 for only. The addition of into an resulted increased uptake lead. dramatic improvement might be attributed increase OH− available binding From the results SEM, XRD, FT-IR analyses, major mechanism lead removal based on dissolution...
To develop potential cosmetic ingredients with antimicrobial and antioxidant activities of 4 Korean bamboo species (P. bambusoides, P. nigra var. henonis, pubescens Sasa coreana) using three different extraction methods-water, ethanol supercritical fluid extraction. Antimicrobial DPPH assay have been examined. Among the against two test strains, Escherichia coli Staphylococcus aureus, extracts 3 trees, pubescens, showed stronger than those extracts. However, dose-dependent increase in...
Meat is an essential source of animal protein that cause many environmental, ethical and economical, social issues nowaday. Due to the growing population, there a limit how much (and/or amino acids) demand can be accommodated by traditional livestock production methods, increasing recognition it necessary convert some deficient into alternative products. In this respect, research on large-scale cultured meat or in-vitro replace existing has been actively conducted worldwide. However, still...
Bamboo leaf has many nutritional and bioactive compounds such as polyphenols, it can be used for various foods application. Fermentation is one of appropriate processes that affect the nutrition, taste flavor, antioxidant activities foods. In this study, a representative domestic bamboo tree (Sasa coreana Nakai) leaves were fermented by Bacillus subtilis KCCM 11315 changes carbohydrates, minerals, amino acids, phenolic investigated before after fermentation. During fermentation period,...
Menopause is characterized by rapid decreases in bone mineral density, aerobic fitness, muscle strength, and balance. In the present study, we investigated effects of new sports tennis type exercise on capacity, follicle stimulating hormone (FSH) N-terminal telopeptide (NTX) postmenopausal women. Subjects were consisted 20 women, who had not menstruated for at least 1 yr follicle-stimulating levels > 35 mIU/L, estradiol levels< 40 pg/mL. The subjects randomly divided into two groups: control...