A5041226186- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Cyclopropane Reaction Mechanisms
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Synthesis and Catalytic Reactions
- Surface Chemistry and Catalysis
- Chemical and Physical Properties in Aqueous Solutions
- Organic Chemistry Cycloaddition Reactions
- Asymmetric Hydrogenation and Catalysis
- Molecular Junctions and Nanostructures
- Organometallic Complex Synthesis and Catalysis
- Catalytic C–H Functionalization Methods
- Ionic liquids properties and applications
- Catalytic Alkyne Reactions
- Thermodynamic properties of mixtures
- Zeolite Catalysis and Synthesis
- Molecular Sensors and Ion Detection
- Process Optimization and Integration
- Synthesis of β-Lactam Compounds
- Phase Equilibria and Thermodynamics
- Supramolecular Self-Assembly in Materials
- Catalysis for Biomass Conversion
- Supramolecular Chemistry and Complexes
Beijing Institute of Technology
2021-2025
Northwestern Polytechnical University
2025
China University of Petroleum, East China
2021-2023
Qingdao University of Technology
2022
Wuhan University of Technology
2022
University of Geneva
2018-2021
Zhejiang University of Technology
2021
Chengdu University of Technology
2021
Shanxi Datong University
2020-2021
Sichuan University
2011-2017
Abstract A highly enantioselective Mannich reaction of silyl ketene imines with isatin‐derived ketimines has been realized by using a chiral N , N′ ‐dioxide/Zn II catalyst. variety β‐amino nitriles containing congested vicinal tetrasubstituted stereocenters were obtained excellent outcomes (up to 98 % yield, >19:1 d.r. and 99 ee ). Based on the experimental investigations, possible transition state proposed explain origin asymmetric induction.
Asymmetric expansion: A catalytic asymmetric ring-expansion reaction of the title compounds occurs in presence a Sc(OTf)(3) catalyst bearing an N,N'-dioxide-based ligand. Highly functionalized 2-quinolone derivatives containing chiral C4-quaternary stereocenter were obtained high yields and levels selectivity under mild conditions (see scheme; Tf=trifluoromethanesulfonyl).
α-Diazoesters were discovered to be good electrophiles in a catalytic asymmetric α-functionalization of ketones for the first time. This reaction also provided direct and efficient method C-N bond formation with excellent yields (up 98%) enantioselectivities 99% ee) under mild conditions. The application electrophilicity α-diazoesters opens up novel way access diversity diazo chemistry.
Biochar is a carbon-rich solid product obtained by pyrolysis of biomass. Here, we investigated multiple biochars produced under slow (235–800 °C), flash carbonization, and hydrothermal carbonization (HTC), using Scanning Electron Microscope—Energy Dispersive X-ray Spectroscopy (SEM-EDX) in order to determine whether SEM-EDX can be used as proxy characterize effectively. Morphological analysis showed that feedstock has an integrated structure compared biochar; more pores were generated, the...
An efficient enantioselective insertion of α-diazoesters and α-diazoketones into O–H bonds carboxylic acids was realized by the use Rh2(OAc)4 a chiral guanidine. Optically active α-acyloxy carbonyl compounds were generated under mild reaction conditions in high yields (up to 99%) good enantioselectivities 97.5:2.5 er).
The combination of catalysis and transport across lipid bilayer membranes promises directional access to a solvent-free structured nanospace that could accelerate, modulate, and, at best, enable new chemical reactions. To elaborate on these expectations, anion with pnictogen tetrel bonds are combined polyether cascade cyclizations into bioinspired cation transporters. Characterized separately, synergistic transporters very high activity identified. Combined for in membranes, found occur...
Highly diastereo- and enantioselective [2 + 2]- [4 2]-cycloadditions of disubstituted ketenes were realized by chiral Lewis acid catalysis. A series arylalkylketenes underwent the reaction smoothly with isatins β,γ-unsaturated α-ketoesters, providing optically active β-lactones δ-lactones vicinal centers in excellent yields (up to 99%) enantioselectivities 99% ee), as well exclusively high diastereoselectivities under 0.2–2 mol % catalyst loading.
Y not? In the presence of L/Y(OTf)3 catalyst, first catalytic asymmetric homologation α-ketoesters with α-alkyl-α-diazoesters through either a 1,2-aryl or 1,2-alkyl shift was accomplished. Highly functionalized succinate derivatives containing quaternary stereocenter were obtained in excellent yield and enantioselectivity under mild reaction conditions. Tf=trifluoromethanesulfonyl. As service to our authors readers, this journal provides supporting information supplied by authors. Such...
A diastereodivergent direct catalytic asymmetric inverse electron demand Diels–Alder reaction between ketenes and 3-alkylenyloxindoles was accomplished by using chiral N,N′-dioxide/gadolinium complexes. By adjusting only the substituents of ligand retaining other catalysis conditions, both syn- anti-indole-fused dihydropyranones bearing two vicinal stereogenic centers were obtained in high yields with excellent ee values. Thus, changing configuration ligands, all stereoisomers could be from...
Abstract A catalytic asymmetric intramolecular homologation of simple ketones with α‐diazoesters was firstly accomplished a chiral N,N′‐dioxide–Sc(OTf) 3 complex. This method provides an efficient access to cyclic α‐aryl/alkyl β‐ketoesters containing all‐carbon quaternary stereocenter. Under mild conditions, variety aryl‐ and alkyl‐substituted ketone groups reacted α‐diazoester smoothly through addition/rearrangement process, producing the in high yield enantiomeric excess.
Epoxide-opening ether cyclizations are shown to occur on π-acidic aromatic surfaces without the need of additional activating groups and with autocatalytic amplification. Increasing activity intrinsic π acidity benzenes, naphthalenediimides (NDIs) perylenediimides (PDIs) support that anion−π interactions account for function. Rate enhancements maximize at 270 catalysis fullerenes 5100 M–1 autocatalysis. The occurrence autocatalysis is confirmed increasing initial rates in presence product....
Asymmetrische Expansion: Ein Sc(OTf)3-Katalysator mit einem N,N′-Dioxid-basierten Liganden bewirkt die katalytische asymmetrische Ringerweiterung der Titelverbindungen. Dabei werden unter milden Reaktionsbedingungen hoch funktionalisierte 2-Chinolone chiralen quartären C4-Stereozentrum in hoher Ausbeute und Selektivität erhalten (siehe Schema; Tf=Trifluormethansulfonyl). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents...
Abstract A highly enantioselective Mannich reaction of silyl ketene imines with isatin‐derived ketimines has been realized by using a chiral N , N′ ‐dioxide/Zn II catalyst. variety β‐amino nitriles containing congested vicinal tetrasubstituted stereocenters were obtained excellent outcomes (up to 98 % yield, >19:1 d.r. and 99 ee ). Based on the experimental investigations, possible transition state proposed explain origin asymmetric induction.
Abstract While the integration of supramolecular principles in catalysis attracts increasing attention, a direct comparative assessment resulting systems catalysts to work out distinct characteristics is often difficult. Herein reported how broad responsiveness ether cyclizations diverse inputs promises fill this gap. Cyclizations confined, π‐basic and Brønsted acidic interior capsules, for instance, are found excel with speed (exceeding general acid hydrogen‐bonding by far) selective...
Ullmann-like on-surface synthesis is one of the most appropriate approaches for bottom-up fabrication covalent organic nanostructures and many successes have been achieved. The Ullmann reaction requires oxidative addition a catalyst (a metal atom in cases): will insert into carbon–halogen bond, forming organometallic intermediates, which are then reductively eliminated form C–C bonds. As result, traditional coupling involves reactions multiple steps, making it difficult to control final...
In this study, a comprehensive characterization was conducted on chiral starburst molecule (C57H48N4, SBM) using scanning tunneling microscopy. When adsorbed onto the hBN/Rh(111) nanomesh, these molecules demonstrate homochiral recognition, leading to selective formation of dimers. Further tip manipulation experiments reveal that dimers are stable and primarily controlled by strong intermolecular interactions. Density functional theory (DFT) calculations supported recognition SBM is governed...
Abstract Conductive hydrogels have garnered widespread attention as a versatile class of flexible electronics. Despite considerable advancements, current methodologies struggle to reconcile the fundamental trade-off between high conductivity and effective absorption-dominated electromagnetic interference (EMI) shielding, dictated by classical impedance matching theory. This study addresses these limitations introducing novel synthesis aramid nanofiber/MXene-reinforced polyelectrolyte...
Abstract Anion‐π catalysis functions by stabilizing anionic transition states on aromatic π surfaces, thus providing a new approach to molecular transformation. The delocalized nature of anion–π interactions suggests that they serve best in long‐distance charge displacements. Aiming therefore for an cascade reaction is as charismatic the steroid cyclization conventional cation‐π biocatalysis, reported here anion‐π‐catalyzed epoxide‐opening ether cyclizations oligomers. Only π‐acidic surfaces...
Edges of low-dimensional quantum systems have profound effects on both fundamental research and device functionality. Real-space investigation the microscopic edge structures understanding edge-modulated electronic properties are great essence. Here we report nanoscale structural reconstruction at atomically sharp a charge-density-wave (CDW) correlated insulator 1T-NbSe2 induced properties. We find CDW unit cells single layer (SL) evolve from well-defined order in bulk spontaneously...