Natalia Derewońko

ORCID: 0000-0003-1045-6602
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Electron Spin Resonance Studies
  • Cytomegalovirus and herpesvirus research
  • Metal complexes synthesis and properties
  • DNA and Nucleic Acid Chemistry
  • Herpesvirus Infections and Treatments
  • Lanthanide and Transition Metal Complexes
  • Catalytic Processes in Materials Science
  • Graphene and Nanomaterials Applications
  • DNA Repair Mechanisms
  • Viral-associated cancers and disorders
  • Nanoparticle-Based Drug Delivery
  • Toxoplasma gondii Research Studies
  • Carcinogens and Genotoxicity Assessment
  • Nanoplatforms for cancer theranostics
  • Microplastics and Plastic Pollution

University of Gdańsk
2016-2025

Gdańsk Medical University
2016-2017

Various types of intercellular connections that are essential for communication between cells often utilized by pathogens. Recently, a new type cellular connection, consisting long, thin, actin-rich membrane extensions named tunneling nanotubes (TNTs), has been shown to play an important role in cell-to-cell spread HIV and influenza virus. In the present report, we show TNTs frequently formed infected alphaherpesvirus, bovine herpesvirus 1 (BoHV-1). Viral proteins, such as envelope...

10.1128/jvi.00090-18 article EN Journal of Virology 2018-03-01

Among metal-based nanoparticles, silver nanoparticles (AgNPs) are particularly appealing because of their stability, functionality, and documented antimicrobial properties. AgNPs also offer the possibility different surface modifications. In this work, we functionalized with thiobarbituric acid or 11-mercaptoundecanoic residues to improve nanoparticles’ biological activities. Subsequently, assessed physicochemical properties newly synthesized using a wide range biophysical methodologies,...

10.3390/nano9070973 article EN cc-by Nanomaterials 2019-07-03

Cancer is a leading cause of death worldwide, with nearly 10 million fatalities yearly. Consequently, despite the search for new therapeutic approaches, use classical chemotherapy, remains one main treatment regimens. Therefore, we evaluate platinum nanoparticles (PtNPs) different sizes as potential modulators doxorubicin (DOX) activity. In presented research, utilized wide range methods, including Spectroscopic measurements, Isothermal Titration Calorimetry, Dynamic Light Scattering, and...

10.1016/j.ejps.2025.107094 article EN cc-by European Journal of Pharmaceutical Sciences 2025-04-01

Graphene oxide (GO), owing to its extraordinary application prospects in biomedicine, is attracting growing research attention. However, the biosafety and blood compatibility of GO required for clearance use clinical trials remain elusive. Therefore, we studied mutagenic properties as well cell toxicity compatibility. Prior biological experiments, assessed structural organization using dynamic light scattering microscopic visualization methods. The results both Ames mutagenicity test...

10.3390/ma18092128 article EN Materials 2025-05-06

One of the greatest challenges modern medicine is to find cheaper and easier ways produce transporters for biologically active substances, which will provide selective efficient drug delivery target cells, while causing low toxicity towards healthy cells. Currently, metal-based nanoparticles are considered a successful viable solution this problem. In work, we propose use novel synthesis method platinum (PtNPs) connected with their precise biophysical characterization assessment potential...

10.1038/s41598-019-41092-6 article EN cc-by Scientific Reports 2019-03-21
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