Young Hwan Choi

ORCID: 0000-0003-1047-1693
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About
Contact & Profiles
Research Areas
  • Tracheal and airway disorders
  • Voice and Speech Disorders
  • Dysphagia Assessment and Management
  • Wound Healing and Treatments
  • Drug-Induced Adverse Reactions
  • Burn Injury Management and Outcomes
  • Simulation-Based Education in Healthcare
  • Cardiac Arrest and Resuscitation
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipoproteins and Cardiovascular Health
  • Electrospun Nanofibers in Biomedical Applications
  • S100 Proteins and Annexins
  • Pressure Ulcer Prevention and Management
  • Vector-Borne Animal Diseases
  • 3D Printing in Biomedical Research
  • Lipid metabolism and disorders
  • Angiogenesis and VEGF in Cancer
  • Cardiac electrophysiology and arrhythmias
  • Anesthesia and Sedative Agents
  • Spinal Fractures and Fixation Techniques
  • Chemotherapy-related skin toxicity
  • Animal Disease Management and Epidemiology
  • Protease and Inhibitor Mechanisms
  • Health and Wellbeing Research
  • Urticaria and Related Conditions

Johns Hopkins University
2022-2025

Johns Hopkins Children's Center
2025

Seoul National University
2012-2022

Chung-Ang University
2012-2022

Sungkyunkwan University
2019-2020

Samsung Medical Center
2019-2020

Seoul National University Hospital
2018-2019

Chung-Ang University Hospital
2019

Government of the Republic of Korea
2019

Bestian Medical Center
2009-2018

In this study, a hydrogel functionalized Janus membrane is developed and its capacity examined as wound dressing biomaterial. A hydrophobic fluoropolymer, poly(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10‐heptadecafluorodecyl methacrylate) (PHFDMA), uniformly coated onto macroporous polyester through initiated chemical vapor deposition process on both sides. PHFDMA‐coated exhibits antibacterial property, allows air permeation, inhibits water penetration. property obtained by exposing one side of...

10.1002/adhm.201600795 article EN Advanced Healthcare Materials 2016-12-20

2][3] Infection with HPV causes disruption of the host's E2 gene, resulting in expression viral oncogenes, E6 and E7.The E7 products inhibit activities tumor suppressors, p53 retinoblastoma protein, respectively.5] Although cervical cancer is 1 highest mortality female patients worldwide, it a curable disease when diagnosed at an early stage. 6However, clear prognostic factors for development are not yet existence.Mitochondria, which cell organelles involved processes life death tumoral...

10.3349/ymj.2009.50.3.399 article EN cc-by-nc Yonsei Medical Journal 2009-01-01

Tissue elasticity is essential to a broad spectrum of cell biology and organ function including the heart. Routine culture models on rigid polystyrene dishes are limited in studying impact tissue distinct regions myocardium such as cardiac conduction system. Gelatin, derivative collagen, simple tunable platform for modeling elasticity. We sought study effects increasing stiffness pacemaker by employing transcription factor-reprogrammed cells cultured gelatin hydrogels with specific Our data...

10.1152/ajpheart.00813.2024 article EN AJP Heart and Circulatory Physiology 2025-03-13

The aim of the present study was to investigate protective effects gomisin A, a lignan compound isolated from Schisandra chinensis, against liver and kidney damage induced by CCl4 exposure. We assessed alterations in organ weights, levels serum biochemical indicators, activation caspase-3 MAPK signaling pathways carried out histological analysis tissue rats pretreated with A for four days. In A/CCl4-treated group, only experienced significant increase weight, whereas other organs did not...

10.3892/ijmm.2013.1263 article EN International Journal of Molecular Medicine 2013-01-31

Objective Most of the literature about Curling's ulcer was published from 1960 through 1980. Therefore, an updated study is needed. We analyzed risk factors affecting incidence in burn patients. Methods retrospectively medical records patients who were admitted to two centers. collected information general characteristics patients, area size, abbreviated severity index, whether surgery performed, endoscopy results, and total body surface (TBSA). performed a multivariate regression analysis...

10.15441/ceem.15.076 article EN cc-by-nc Clinical and Experimental Emergency Medicine 2015-12-28

Yes-associated protein 1 (YAP1) is a key transcriptional regulator in the Hippo signaling pathway that plays critical role development and progression of several types malignancies, including ovarian cancer. Herein, we investigated expression YAP1 its clinical significance large population patients with serous cystadenocarcinoma (OSC), which most common form epithelial neoplasm, using TCGA database. Surprisingly, cross-cancer mRNA alterations were higher OSC than those other cancers was...

10.3892/or.2017.5517 article EN cc-by-nc-nd Oncology Reports 2017-03-21

Rifampin is commonly used as a first-line anti-tuberculosis drug, but it can induce serum sickness-like reaction or anaphylaxis. However, possible for 1 drug antigen to 2 more simultaneous immunologic reactions. Here, we report case of serum-sickness-like and anaphylaxis induced concurrently by rifampin. A 25-year-old male presented with high fever maculopapular rash vesicles on the hands, which developed weeks following regular administration drugs tuberculous meningitis, including Elevated...

10.4168/aair.2014.6.2.183 article EN Allergy Asthma and Immunology Research 2014-01-01

Background: Patients with chronic kidney disease have had conflicting results between drug-eluting stents (DES) and bare-metal (BMS). The aim of the present study was to determine whether DES is preferable for treatment acute myocardial infarction (AMI) renal insufficiency, elucidate impact diabetes mellitus (DM) on outcomes each stent. Methods Results: As a part Korea Acute Myocardial Infarction Registry (KAMIR), 2,175 AMI patients insufficiency (glomerular filtration rate <60ml/min)...

10.1253/circj.cj-11-0586 article EN Circulation Journal 2011-01-01

Background: The question as to whether triple antiplatelet therapy is superior dual for patients with acute myocardial infarction (AMI) and renal dysfunction, who undergo percutaneous coronary intervention (PCI), unresolved. Methods Results: As part of the Korea Acute Myocardial Infarction Registry (KAMIR), 2,288 AMI dysfunction (glomerular filtration rate <60ml/min·1.73m2) received either (aspirin plus clopidogrel; n=1,587) or clopidogrel cilostazol; n=701) therapy. Major adverse cardiac...

10.1253/circj.cj-12-0236 article EN Circulation Journal 2012-01-01

Immediate contralateral epidural hematoma (EDH) and traumatic intracerebral (T-ICH) after craniectomy for subdural (SDH) are rare but devastating post-operative complications. Their clinical features outcomes not well studied. In this report, we present the of immediate acute cases requiring a second operation.This study includes 10 EDH T-ICH following bilateral evacuation SDH between 2004 2015. medical records radiographic findings were reviewed analyzed retrospectively.Ten 528 patients...

10.13004/kjnt.2017.13.2.108 article EN Korean Journal of Neurotrauma 2017-01-01

WKYMVm hexapeptide has been identified as a strong FPR2 agonist through library screening of synthetic peptides. The reported to play crucial role in inflammation and angiogenic responses via stimulation chemotaxis, migration, cell proliferation, wound healing vessel growth. Recently, the therapeutic effects have various disease models. In cutaneous model diabetic mice, facilitated processes by stimulating formation capillary arteriole re-epithelialization. coronary artery stenosis model,...

10.1080/15476278.2016.1172155 article EN Organogenesis 2016-04-02

The effects of fenofibrate on C-reactive protein (CRP) are under debate. We investigated the effect CRP levels and variables determining changes.This case-control study enrolled 280 hypertriglyceridemic patients who were managed either with 200 mg (Fenofibrate group, n=140) or standard treatment (comparison n=140). measured before after management for 2 months.CRP decreased in both (p=0.003) comparison (p=0.048) groups. Changes not significantly different between two groups (p=0.27)...

10.4070/kcj.2012.42.11.741 article EN Korean Circulation Journal 2012-01-01

Various growth factor delivery systems were used in the treatment of glottal insufficiency; however, relatively little attention has been paid to a gene system for aspects active vocal fold (VF) regeneration. Herein, we present plasmid DNA (pDNA; bFGF encoding) complex-loaded alginate (ALG)/hyaluronic acid (HA) mixture hydrogel dispersed with polycaprolactone (PCL) microspheres that can enhance simultaneous regeneration VF muscle and lamina propria, as well have bulking effect on atrophied...

10.1021/acsbiomaterials.8b01541 article EN ACS Biomaterials Science & Engineering 2019-01-22
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