- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Sarcoma Diagnosis and Treatment
- Spinal Hematomas and Complications
- Blood transfusion and management
- Spinal Fractures and Fixation Techniques
- Cancer Diagnosis and Treatment
- Cancer Cells and Metastasis
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Malaria Research and Control
- Brain Metastases and Treatment
- Mosquito-borne diseases and control
- Pancreatic and Hepatic Oncology Research
- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Global Maternal and Child Health
- Cancer Genomics and Diagnostics
- Head and Neck Cancer Studies
- Cancer Research and Treatments
- Infectious Diseases and Tuberculosis
- Musculoskeletal pain and rehabilitation
- 3D Printing in Biomedical Research
- Scoliosis diagnosis and treatment
- Pelvic and Acetabular Injuries
National University Health System
2014-2025
Myanmar Oxford Clinical Research Unit
2021-2023
National University Hospital
2014-2018
Singapore General Hospital
2015
University Health System
2014
Study Design: Prospective cohort study. Summary of Background Data: Minimally invasive spinal surgery (MISS) has been gaining recognition in patients with metastatic spine disease (MSD). The advantages are reduction blood loss, hospital stay, and postoperative morbidity. Most the studies were case series very few comparing outcomes MISS to open approaches. Objective: To evaluate compare clinical perioperative versus approach symptomatic MSD, who underwent posterior stabilization and/or...
In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity mortality. Village health workers (VHWs) are often the first point contact with formal system, patients they can provide early diagnosis treatment malaria. However, majority patients, VHWs lack training, support resources to further care. Consequently, treatable bacterial missed, antibiotics overused poorly targeted, patient attendance wanes along This Open Letter...
A retrospective study of 180 patients with lung cancer spinal metastases, wherein prognostic score-predicted survival was compared actual survival.To evaluate and compare the accuracy scoring systems in metastases.The modified Tokuhashi, Tomita, Bauer, Oswestry scores are currently used to guide decisions regarding operative treatment metastases. The best system for predicting metastases remains undetermined. high incidence from improved treated systemic therapy warrants evaluation these...
BACKGROUND Despite advances in surgical techniques for spinal metastases, there is often substantial blood loss, resulting patients requiring transfusion during the perioperative period. Allogeneic (ABT) has been main replenishment method lost blood. However, impact of ABT on cancer‐related outcomes controversial various studies. We aimed to evaluate influence disease progression and survival undergoing metastatic tumor surgery (MSTS). STUDY DESIGN AND METHODS conducted a retrospective study...
BACKGROUND The question of independent association between allogeneic blood transfusion (ABT) and postoperative complications in cancer surgeries has been controversial remains so. In metastatic spine tumor surgery (MSTS), previous studies investigated the influence ABT on survival, but not complications. We aimed to evaluate perioperative infections patients undergoing MSTS. STUDY DESIGN AND METHODS This retrospective study included 247 who underwent MSTS at a single tertiary institution...
<ns3:p>In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity mortality. Village health workers (VHWs) are often the first point contact with formal system, patients they can provide early diagnosis treatment malaria. However, majority patients, VHWs lack training, support resources to further care. Consequently, treatable bacterial missed, antibiotics overused poorly targeted, patient attendance wanes along...
Background Myanmar has a large majority of all malaria in the Greater Mekong Subregion. In past decade, substantial progress was made control. The residual burden is remote areas where currently recommended elimination approaches are generally not feasible. such hard-to-reach communities Mon state, East Myanmar, Medical Action introduced community health workers (CHWs) to deliver early diagnosis and treatment for malaria. We conducted retrospective analysis assess impact this intervention....
Study Design. A retrospective study of all patients with histologically confirmed breast cancer spinal metastases presenting to a single institution between May 2001 and April 2012. Objectives. The aim this was investigate whether the 2014mT is more accurate than 2005mT. Summary Background Data. commonly used 2005 modified Tokuhashi score (2005mT) has become inaccurate as oncologists move toward treating tumors according their molecular genomic profile, rather tissue-of-origin. In attempts...
Retrospective analysis.Recent advancements in systemic treatment of lung cancer have significantly improved the survival patients with certain histolopathologic and molecular subtypes. Existing prognostic scores do not account for this spinal metastases are grouped together as poor candidates, consequently, some may be inappropriately denied palliative spine surgery.The objective study was to whether expected is affected by subtypes context modern therapy.We retrospectively reviewed all...
Prospective analysis.To evaluate 2-year clinical outcomes in patients undergoing Disc-FX for the management of low back pain (LBP) due to degenerate disc (DD) or contained lumbar herniation (CLDH). To study salient factors that can potentially influence outcomes.We analyzed prospectively collected data 51 who underwent procedure DD CLDH, nonresponsive 6 months nonoperative treatment. Clinical outcome measures were visual analogue scale (VAS), Oswestry Disability Index (ODI), and MacNab...