A5103119456- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Renal cell carcinoma treatment
- Cancer-related molecular mechanisms research
- Pancreatic and Hepatic Oncology Research
- Osteoarthritis Treatment and Mechanisms
- Orthopedic Infections and Treatments
- Organ Transplantation Techniques and Outcomes
- Bladder and Urothelial Cancer Treatments
- Cancer, Lipids, and Metabolism
- Pancreatitis Pathology and Treatment
- Orthopaedic implants and arthroplasty
- Coconut Research and Applications
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- MicroRNA in disease regulation
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
- Total Knee Arthroplasty Outcomes
First Affiliated Hospital of Harbin Medical University
2021-2024
Harbin Medical University
2021-2024
First Affiliated Hospital of GuangXi Medical University
2021-2022
Guangxi Medical University
2020-2022
Second Hospital of Anhui Medical University
2020
Anhui Medical University
2020
Oxidative stress (OS) responses have been linked to oncogenesis and tumor progression recently regarded as a potential strategy for therapy. However, OS-related therapeutic targets not identified date in the bladder cancer (BC).The mRNA expression clinical data of BC were downloaded from public database. Prognostic risk score signature was constructed using LASSO Cox regression analysis. External validation performed GSE15307 cohort. ESTIMATE, CIBERSORT, ssGSEA algorithm used analyze immune...
Oxidative stress is commonly associated with osteoarthritis (OA). Lycopene (LYC), a natural carotenoid compound, an effective antioxidant potential cartilage‐protecting actions. However, how it affects hydrogen peroxide (H 2 O )‐induced damage to the cartilage unclear. In this study, in vitro oxidative model was developed via treating primary chondrocytes H . Western blot, immunohistochemistry, and quantitative RT‐PCR (qRT‐PCR) were used assess levels of related factors. Reactive oxygen...
Abstract Necroptosis, a type of programmed cell death, has become potential therapeutic target for solid tumors. Nevertheless, the roles necroptosis-related genes (NRGs) in gastric cancer (GC) remain unknown. The objective present study was to create prognostic signature that can provide more accurate assessment prognosis GC. Using Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) data, we identified differentially expressed NRGs. Univariate analysis Lasso regression were...
Ferroptosis is linked to various tumor biological traits, and alternative splicing (AS), a crucial step in mRNA processing, plays role the post-transcriptional regulation of ferroptosis-related genes (FRGs). A least absolute shrinkage selection operator (LASSO) penalized Cox regression analysis was utilized build prognostic signature based on 12 AS events (p < 0.05), which validated gastric cancer (GC) patients. The high-risk group (n = 203) showed enrichment metastasis pathways 0.05)....
Abstract Background: Increasing evidence has shown that hypoxia is closely related to the development, progression and prognosis of clear cell renal carcinoma (ccRCC). Nevertheless, reliable prognostic signatures based on have not been well-established. This study aimed construct an optimized nomogram hypoxia-related genetic for patients with ccRCC. Method: We accessed hallmark gene sets hypoxia, including 200 genes, original RNA seq dataset ccRCC cases integrated clinical information...
To investigate the effect of Navio robot-assisted unicompartmental knee arthroplasty (UKA) on biomechanics joint during sitting-up movement, and to determine whether UKA can maintain biomechanical characteristics joint.The clinical data 8 patients with medial compartment osteoarthritis treated fixed platform between January 2018 2019 had complete follow-up were retrospectively analyzed. There 4 males females; age ranged from 58 67 years, an average 62.3 years. The disease duration was 6-18...