A5016904016- Trypanosoma species research and implications
- Ion channel regulation and function
- Venomous Animal Envenomation and Studies
- Curcumin's Biomedical Applications
- Beetle Biology and Toxicology Studies
- Nicotinic Acetylcholine Receptors Study
- Mitochondrial Function and Pathology
- Research on Leishmaniasis Studies
- Pharmacological Effects of Medicinal Plants
- Plasma Applications and Diagnostics
- Electrohydrodynamics and Fluid Dynamics
- Helminth infection and control
- Parasites and Host Interactions
- Erythrocyte Function and Pathophysiology
- Cardiomyopathy and Myosin Studies
- Toxin Mechanisms and Immunotoxins
- Rabbits: Nutrition, Reproduction, Health
- Ginger and Zingiberaceae research
Universidad Autónoma del Estado de México
2013-2024
Instituto Politécnico Nacional
2024
Centro de Investigación en Materiales Avanzados
2024
Center for Research and Advanced Studies of the National Polytechnic Institute
2024
The efforts for the development and testing of vaccines against Trypanosoma cruzi infection have increased during past years. We designed a TcVac series composed T. derived, GPI-anchored membrane antigens. been shown to elicit humoral cellular mediated immune responses provide significant (but not complete) control experimental in mice dogs. Herein, we aimed test two immunization protocols delivery DNA-prime/DNA-boost vaccine (TcVac1) TcG2 TcG4 antigens BALB/c mouse model. Mice were...
The aim of this study is to determine the toxic and genotoxic damages produced by a helium plasma needle upon HeLa E. coli (OG100 PQ30) cell cultures. For cells survival (MTT) microelectrophoresis comet) assays were performed; meanwhile in coli, viable count genotoxicity chromotest evaluated. outcomes indicate that exposures on undergo more toxicity as treatment time increases. With respect exposure generated toxicity, but no could be detected with system. In strain OG100, defective...
The venom of Centruroides limpidus (Cll) is a mixture pharmacologically active principles. most important these are toxic proteins that interact both selectively and specifically with different cellular targets such as ion channels. Recently, anticancer properties the from other scorpion species have been described. Studies in vitro shown induces cell death, inhibits proliferation triggers apoptotic pathway cancer lines. Herein, after treating human cervical adenocarcinoma (HeLa) cells Cll...
During Trypanosoma cruzi infection, oxidative stress is considered a contributing factor for dilated cardiomyopathy development. In this study, the effects of astaxanthin (ASTX) were evaluated as an alternative drug treatment Chagas disease in mouse model during acute infection phase, given its anti-inflammatory, immunomodulating, and anti-oxidative properties. ASTX was tested vitro parasites grown axenically co-culture with Vero cells. vivo tests performed BALB/c mice (4-6 weeks old)...
Chagas disease predominantly affects the heart, esophagus, and colon in its chronic phase. However, precise infection mechanisms of causal agent Trypanosoma cruzi these tissue types remain incompletely understood. This study investigated T . dynamics skeletal (SM) cardiac myotubes (CM) differentiated from H9c2(2–1) myoblasts (control). SM CM were generated using 1% fetal bovine serum (FBS) without or with retinoic acid, respectively. Initial invasion efficiencies numbers released parasites...
Biologically active molecules present in the venom of several species scorpion, have shown potential against various diseases, including cancer. It has been reported that toxins can block ion channels membrane cancer cell lines, through action potential, altering their function, cycle arresting, and inducing apoptosis death pathway. The use sequence Cll-6 gene genome Mexican scorpion Centruroides limpidus encoding a beta-toxin-locker Na + by potentials is proposed. This molecule not...