A5019371803- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Breast Implant and Reconstruction
- Prostate Cancer Treatment and Research
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Breast Lesions and Carcinomas
- Endometrial and Cervical Cancer Treatments
- Neuroblastoma Research and Treatments
- Advanced MRI Techniques and Applications
- Advances in Oncology and Radiotherapy
- Ocular Oncology and Treatments
- Lung Cancer Treatments and Mutations
- Advanced X-ray and CT Imaging
- Lung Cancer Research Studies
- Management of metastatic bone disease
- Effects of Radiation Exposure
- Optical Coherence Tomography Applications
Washington University in St. Louis
2016-2025
Jewish Hospital
2016
Barnes-Jewish Hospital
2016
Purpose Yttrium‐90 ( 90 Y) microsphere radioembolization enables selective internal radiotherapy for hepatic malignancies. Currently, there is no standard postdelivery imaging and dosimetry of the distribution to verify treatment. Recent studies have reported utilizing small positron yield Y (32 ppm) with emission tomography (PET) perform treatment verification analysis. In this study, we validated a commercial software, MIM SurePlan™ LiverY90 (MIM Software Inc., Cleveland, OH), clinical...
Prostate-specific membrane antigen (PSMA) is a cell surface protein highly expressed in nearly all prostate cancers, with restricted expression some normal tissues. The differential of PSMA from tumor to non-tumor tissue has resulted the investigation numerous targeting strategies for therapy patients metastatic cancer. In March 2022, FDA granted approval use lutetium-177 PSMA-617 (Lu-177-PSMA-617) PSMA-positive castration-resistant cancer (mCRPC) who have been treated androgen receptor...
Our purpose was to describe the risk of radiation-induced brachial plexopathy (RIBP) in patients with breast cancer who received comprehensive adjuvant radiation therapy (RT).Records for 498 RT (treatment any residual tissue, underlying chest wall, and regional nodes) between 2004 2012 were retrospectively reviewed. All treated conventional 3 5 field technique (CRT) until 2008, after which intensity modulated (IMRT) introduced. RIBP events determined by reviewing follow-up documentation from...
Radioembolization with yttrium-90 (Y-90) is utilized to treat primary liver malignancies. The efficacy of this intra-arterial therapy in arterially hypoperfused tumors not known.
The purpose of this study was to describe the clinical implementation a magnetic resonance image (MRI)-based approach for adaptive intracavitary brachytherapy (ICBT) cervix cancer patients. Patients were implanted with titanium tandem and colpostats. MR imaging performed on 1.5-T Philips scanner using T2-weighted (T2W), proton-density weighted (PDW), diffusion-weighted (DW) sequences. Apparent diffusion coefficient (ADC) maps generated from DW images. All images fused. T2W used definition...
There is growing interest among pediatric institutions for implementing iodine-131 (I-131) meta-iodobenzylguanidine (MIBG) therapy treating children with high-risk neuroblastoma. Due to regulations on the medical use of radioactive material (RAM), and complexity safety risks associated procedure, a multidisciplinary team involving radiation therapy/safety experts required. Here, we describe methods I-131 MIBG evaluate our program's robustness via failure modes effects analysis (FMEA).We...
High-dose-rate brachytherapy (HDR-BT) delivered in a single fraction as monotherapy is potential treatment modality for low- and intermediate-risk prostate cancer (LIR-PC); however, outcome data with this technique remain limited. Here we describe our institutional HDR experience report the efficacy toxicity of treatment.LIR-PC patients who received definitive HDR-BT during 2013-2017 were retrospectively identified. The intended dose was 19 Gy one fraction. Acute (< 90 days) late (≥ assessed...
Abstract Purpose Characterize the intra‐fraction motion management ( IFMM ) system found on Gamma Knife Icon GKI ), including spatial accuracy, latency, temporal performance, and overall effect delivered dose. Methods A phantom was constructed, consisting of a three‐axis translation mount, remote motorized flipper, thermoplastic sphere surrounding radiation detector. An infrared marker placed mount secured to flipper. The accuracy measured via in all Cartesian planes. detector centered at...
Obese patients constitute 40% of the adult population. MRIs obese are typically challenging because effects a large field view on image quality and increased risk thermal burns from contact with bore. In this case report, impacts obesity MRI procedures safety introduced. Then is presented 30-year old female cervical cancer patient who received an simulation to verify placement titanium tandem colpostats for brachytherapy. A magnetic susceptibility artifact was detected near right pelvis...
Yttrium-90 (90Y) radioembolization with an escalated dose has been shown to improve clinical outcomes compared standard radioembolization, but there are few data on the local control of primary liver tumors. We reported patients unresectable tumors treated 90Y dose.Clinical hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and biphenotypic (cHCC-CC) (≥150 Gy) between 2013 2020 >3 months follow-up were retrospectively reviewed. The endpoint was freedom from progression. Clinical...
Magnetic resonance imaging (MRI) plays an increasingly important role in brachytherapy planning for cervical cancer. Yet, metal tandem, ovoid intracavitary applicators, and fiducial markers used cause magnetic susceptibility artifacts standard MRI. These may impact the accuracy of treatment evaluation tumor response by misrepresenting size location implant, distorting surrounding anatomy tissue. Metal artifact reduction sequences (MARS) with high bandwidth RF selective excitations turbo...