A5001507055- Clinical Laboratory Practices and Quality Control
- Bacterial Identification and Susceptibility Testing
- Chronic Kidney Disease and Diabetes
- Metabolomics and Mass Spectrometry Studies
- Transplantation: Methods and Outcomes
- Reliability and Agreement in Measurement
- Sulfur Compounds in Biology
- Hemoglobinopathies and Related Disorders
- Pesticide Exposure and Toxicity
- Redox biology and oxidative stress
- Hematological disorders and diagnostics
- Advanced Glycation End Products research
- Neonatal Health and Biochemistry
- Growth Hormone and Insulin-like Growth Factors
- Parathyroid Disorders and Treatments
- Cholesterol and Lipid Metabolism
- Biosimilars and Bioanalytical Methods
- Urinary Tract Infections Management
- Blood groups and transfusion
- Blood properties and coagulation
- Meta-analysis and systematic reviews
- Diet and metabolism studies
- Biotin and Related Studies
- Iron Metabolism and Disorders
- Muscle metabolism and nutrition
Ministry of Health
2019-2024
Memorial Ankara Hospital
2020-2021
Harran University
2020
Ankara Numune Eğitim ve Araştırma Hastanesi
2020
Sağlık Bilimleri Üniversitesi
2019
Bozok Universitesi
2018
Türkiye Yüksek İhtisas Hastanesi
2015-2016
Abstract Objectives Serum cholinesterase (ChE) 3.1.1.8 is measured to assess exposure organophosphorus pesticides and determine deficiency related prolonged apnea after the induction of anesthesia with certain drugs less often as an indicator liver function. Biological variation (BV) accepted endogenous source that contributes total in laboratory medicine. No data on BV serum ChE have been found European Federation Clinical Chemistry Laboratory Medicine database. Thus, this study aimed...
Measurement of parathyroid hormone (PTH) is essential in the investigation and management calcium metabolism disorders. To assess significance any assay result when clinical decision making biological variation (BV) measurand must be taken into consideration. The aim present study determining BV parameters for serum PTH.Blood samples were at weekly intervals from 20 healthy subjects ten weeks this prospective study. Serum "intact PTH" concentrations measured with electrochemiluminescence...
Background Selection and verification of blood collection tubes is an important preanalytical issue in clinical laboratories. Today, gel are commonly used with many advantages, although they known to cause interference immunoassay methods. In this study, we aimed compare SST s two different suppliers (Ayset clot activator & Gel Becton Dickinson ( BD ) Vacutainer II advance) reference evaluate the effect storage time terms endocrine tests such as thyroid‐stimulating hormone TSH ), free...
Abstract Objective Hemoglobinopathies are a common public health problem in Turkey. In the screening of these disorders population, cation-exchange high performance liquid chromatography (HPLC) is accepted as gold standard method. this study, aim was to assess four different HPLC devices used hemoglobinopathy screening. Materials and methods A total 58 blood samples were analyzed with (Bio-Rad variant II, Agilent 1100, Tosoh G8 Trinity Ultra2 trademarks). Results The comparison study...
The current study aimed to assess the interference of in vitro haemolysis on complete blood count (CBC) using Abbott Alinity hq system, and determine which levels affect reliability sample results.Blood samples obtained from 25 volunteers K3-EDTA tubes were divided into four aliquots. first aliquot was not subjected any intervention. second, third fourth aliquots passed through a fine needle 2, 4 6 times, respectively. Complete performed by multi-angle polarized scatter separation technology...
Biotinidase Deficiency (BD) is an autosomal recessive metabolic disorder. However, the relationship between genotype and biochemical phenotype has not been completely elucidated yet. But still, some mutations are accepted to be associated with profound or partial deficiency. We aimed evaluate results of enzyme activity in accordance presence genetic investigate correlation together study.This retrospective study was carried out using data from medical records 133 infants detected by newborn...
In this study, we investigated dynamic thiol-disulfide homeostasis as a new indicator of oxidative stress in lung transplant recipients. addition, compared parameters according to indication and time after transplant.
Abstract Objective Macroprolactinemia detection is important to avoid unneccessary tests and overtreatment. High prolactin levels require routine screening clinicians must be aware of macroprolactinemia frequency encountered with the method in use. In this study we aimed determine rate our laboratory. Methods Prolactin results different patients analysed on two immunoassay systems within consecutive years were evaluated. Analyses performed Beckman Coulter UniCel ® DxI800 Roche Cobas e601...
Abstract Objectives Inborn errors of metabolism are generally autosomal recessive inherited disorders. The incidence and genetic features neonatal metabolic disorders vary significantly by regions populations. In this study, we aimed to determine the amino acid evaluate test results these patients retrospectively. Methods blood samples collected from heel dried on filter cards in screening program, were analyzed for (LC)-MS/MS method. Patients with suspected diseases diagnosed NGS Results...
Amaç: Kolesterol esterleri, sfingolipidler ve gliserolipitler gibi hücresel lipitler, Yağ asitleri (YA) içerir. YA'lar birçok canlı yapıda yer almakta bazı hastalıkların teşhisinde incelenmesinde kullanılmaktadır. 22 veya daha fazla karbon atomu içeren çok uzun zincirli yağ (ÇUZYA'lar) olarak tanımlanır. Bu çalışmada Ankara Bilkent Şehir Hastanesi'nin ÇUZYA analiz verilerinin sonuçlarının değerlendirilmesi literatüre katkı sunulması amaçlandı. Gereç Yöntemler: çalışmaya toplam 5973 C22:0,...
Abstract Objectives Recent advances in hematology analyzers have enabled to improve the reliability results and also provided additional hematological parameters. In present study, we aimed determine reference ranges for automated erythrocyte reticulocyte parameters healthy individuals on Sysmex XN 1000 analyzer. Methods One hundred thirty-three subjects with normal physical examination complete blood count within were included study. Venous samples collected tubes containing K 2 -EDTA...
Increased urine albumin excretion is suggested to be an early marker of glomerular damage. Evaluation a test’s performance characteristics such as diagnostic sensitivity and specifictiy necessity before application into routine practice. To our knowledge up now there no study evaluating Dirui test strips for albuminuria determination. Therefore the objective this was these agreement with established method used in laboratory. Freshly collected 177 specimens were included study. Strips read...
Amaç: Serum tiroid hormon düzeyleri hastalıklarının tanı ve takibinde kullanılır. Bu çalışma serum tirotropin (TSH) için biyolojik varyasyonu (BV) hesaplanması değerlendirilmesini amaçlamaktadır. Gereç yöntemler: Kan örnekleri, sekiz gönüllüden (dört kadın, dört erkek; yaşları 20-35 arasında değişen) beş hafta boyunca, haftalık olarak alındı. TSH seviyeleri Abbott Architect ci8200 immunassay cihazında ölçüldü Biyolojik varyasyon hesaplamaları Fraser’ın yöntemine göre nested ANOVA testi...
Amaç: Böbrek fonksiyonun bir belirteci olarak bilinen sistatin C’nin tümör gelişiminde inhibör etki gösterdiği düşünülmektedir. Çalışmada böbrek hastalığı olmayan mide ve kolorektal kanserli olgularla sağlıklı bireylerin serum C düzeyleri arasındaki olası farkın, karsinoembriyonik antijen (CEA) karbohidrat 19-9 (CA19-9) ilişkinin incelenmesi amaçlanmıştır.Materyal metod: Çalışmaya kreatinin konsantrasyonu referans aralığı içerisinde yer alan tahmini glomerüler filtrasyon hızı (eGFH)...
Oxidative stress developing due to oxidant/antioxidant imbalance plays a crucial role in the etiopathogenesis of chronic progressive lung diseases.The condition is typically more severe transplant candidates with end-stage disease. Here, we investigated dynamic thiol-disulfide homeostasis as marker for oxidative candidates.The study included 40 patients disease indications (candidate group) and healthy controls. Patient demographic data, laboratory results, values were recorded. We...