Mike Mach

ORCID: 0000-0003-1109-4623
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About
Contact & Profiles
Research Areas
  • Transcranial Magnetic Stimulation Studies
  • Treatment of Major Depression
  • Digital Mental Health Interventions
  • Functional Brain Connectivity Studies

Alberta Health Services
2020-2023

Background: Treatment-resistant depression (TRD) is considered one of the major clinical challenges in field psychiatry. An estimated 44% patients with depressive disorder (MDD) do not respond to two consecutive antidepressant therapies, and 33% up four antidepressants. Over 15% all MDD remain refractory any treatment intervention. rTMS a option for TRD. Likewise, iCBT evidence-based, symptom-focused psychotherapy recommended Objective: This study aimed evaluate initial comparative...

10.3390/brainsci13020293 article EN cc-by Brain Sciences 2023-02-09

Major depression is a severe, disabling, and potentially lethal clinical disorder. Only about half of patients respond to an initial course antidepressant pharmacotherapy. At least 15% all with major depressive disorder (MDD) remain refractory any treatment intervention. By the time that patient has experienced 3 definitive failures, likelihood achieving remission fourth option offered below 10%. Repetitive transcranial magnetic stimulation (rTMS) considered for MDD who are treatment. It not...

10.2196/18843 article EN cc-by JMIR Research Protocols 2020-08-11

<sec> <title>BACKGROUND</title> Major depression is a severe, disabling, and potentially lethal clinical disorder. Only about half of patients respond to an initial course antidepressant pharmacotherapy. At least 15% all with major depressive disorder (MDD) remain refractory any treatment intervention. By the time that patient has experienced 3 definitive failures, likelihood achieving remission fourth option offered below 10%. Repetitive transcranial magnetic stimulation (rTMS) considered...

10.2196/preprints.18843 preprint EN 2020-03-23
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