A5031542006- Advanced Photocatalysis Techniques
- Ga2O3 and related materials
- Gas Sensing Nanomaterials and Sensors
- 2D Materials and Applications
- Monoclonal and Polyclonal Antibodies Research
- Protein purification and stability
- Pesticide Exposure and Toxicity
- Cholinesterase and Neurodegenerative Diseases
- Extracellular vesicles in disease
- Computational Drug Discovery Methods
- Viral Infectious Diseases and Gene Expression in Insects
- Glycosylation and Glycoproteins Research
- Advanced biosensing and bioanalysis techniques
- Chemical Synthesis and Analysis
- Graphene and Nanomaterials Applications
- Carbon Nanotubes in Composites
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- HER2/EGFR in Cancer Research
BeiGene (China)
2025
The Ohio State University
2017-2021
Jiangsu University
2017-2018
Carbon nanotubes (CNTs), one of the unique one-dimensional nanomaterials, have gained great attention because their specific characters, versatile functionalization chemistry, and biological compatibility in past few decades. CNTs can be functionalized via different methods to perform functions. been used various areas biomedicine as nanocarriers, including cancer diagnosis therapy. Different molecules such peptide, antigen, nucleic acid delivered cells by with high efficiency. In this...
2D/2D SnO<sub>2</sub>/GL-C<sub>3</sub>N<sub>4</sub>photocatalysts with large specific surface area and high coupling heterointerface extent were synthesized by an environmental friendly hydrothermal method, showing excellent photocatalytic performance on RhB degradation.
Novel two-dimensional (2D) metal-free few-layer BN/graphene-like g-C3N4 (2D BN/g-C3N4) composites have been synthesized by a simple hydrothermal method. The construction of 2D/2D structure between BN and could shorten the migration distance charge transfer, provide large contact surface. By introducing nanosheets into g-C3N4, as-prepared 2D BN/g-C3N4 exhibited much enhanced photocatalytic performance than that pure g-C3N4. 0.5% composite possessed most wonderful ability towards Rhodamine B...
3D WO<sub>3</sub> nanoparticle/h-BN nanosheet composites (WO<sub>3</sub>/BN) have been designed and fabricated by a simple <italic>in situ</italic> one-step calcination method.
Conventional column chromatography processes to purify recombinant proteins are associated with high production costs and slow volumetric throughput at both laboratory large scale. Non-chromatographic purifications based on selective aggregating tags have the potential reduce acceptable protein yields. A significant drawback, however, is that current proteolytic approaches for post-purification tag removal after expensive non-scalable. To address this problem, we developed two...
Abstract The purification of recombinant proteins is a complicated process that requires thorough understanding the physical and chemical properties each protein interest. unique characteristics require development complicated, multi‐step consisting several orthogonal chromatographic techniques. Although affinity tag methods have been useful in simplifying this process, these approaches significant drawbacks when tagless are required. Therefore, flexible, economical, efficient platform for...
Drug-to-antibody ratio (DAR), free-drug-related impurities (FDRI) content, and purity are critical quality attributes of antibody-drug conjugates (ADCs), which substantially impact product safety efficacy. However, growing efforts in developing ADCs with higher complexity a faster timeline impose great challenge to their analytical support. Herein, for the ADC carries an antibody linker-payload distinct UV/vis absorption maxima, we propose high-throughput multiattribute analysis strategy...
Chemical warfare nerve agents (CWNAs) present a global threat to both military and civilian populations. The acute toxicity of CWNAs stems from their ability effectively inhibit acetylcholinesterase (AChE). This inhibition can lead uncontrolled cholinergic cellular signaling, resulting in crisis and, ultimately, death. Although the current FDA-approved standard care is moderately effective when administered early, development novel treatment strategies necessary. Butyrylcholinesterase (BChE)...