A5005236794- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- Meningioma and schwannoma management
- Medical Imaging Techniques and Applications
- Acute Ischemic Stroke Management
- Head and Neck Surgical Oncology
- Moyamoya disease diagnosis and treatment
- Glioma Diagnosis and Treatment
- Trigeminal Neuralgia and Treatments
- Fetal and Pediatric Neurological Disorders
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Lysosomal Storage Disorders Research
- Glycogen Storage Diseases and Myoclonus
- Vascular Malformations and Hemangiomas
- Radiation Detection and Scintillator Technologies
- Cerebral Venous Sinus Thrombosis
- Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Pituitary Gland Disorders and Treatments
Policlinico S.Orsola-Malpighi
2024
Maria Cecilia Hospital
2024
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2019-2023
University of Messina
2013-2022
Ospedale San Bortolo
2020-2022
Azienda di Rilievo Nazionale ed Alta Specializzazione
2022
Vanderbilt University Medical Center
2021
University of Insubria
2021
Sapienza University of Rome
2014-2020
Morpho (United States)
2015-2019
<h3>BACKGROUND AND PURPOSE:</h3> MR imaging tractography is increasingly used to perform noninvasive presurgical planning for brain gliomas. Recently, constrained spherical deconvolution was shown overcome several limitations of commonly DTI tractography. The purpose our study evaluate WM tract alterations both the corticospinal and arcuate fasciculus in patients with high-grade gliomas, through qualitative quantitative analysis probabilistic tractography, reliable planning. <h3>MATERIALS...
Background and Purpose: To evaluate outcome safety of endovascular treatment beyond 6 hours onset ischemic stroke due to large vessel occlusion in the anterior circulation, routine clinical practice. Methods: From Italian Registry Endovascular Thrombectomy, we extracted data patients treated for known hours. Additional inclusion criteria were prestroke modified Rankin Scale score ≤2 ASPECTS ≥6. Patients selected on individual basis by a combination CT perfusion mismatch (difference between...
The differential diagnosis between radiation necrosis, tumor recurrence and progression is crucial for the evaluation of treatment response planning. appearance treatment-induced tissue necrosis on conventional Magnetic Resonance Imaging (MRI) similar to brain it could be difficult differentiate two entities follow-up MRI examinations. Dynamic Susceptibility Contrast-enhanced (DSC) Contrast-Enhanced (DCE) are perfusion techniques that use an exogenous, intravascular, non-diffusible...
Molecular signaling that leads to brain arteriovenous malformation (bAVM) is date elusive and this firstly due the low frequency of familial cases. Conversely, sporadic bAVM most diffuse condition represents main source characterize genetic basis disease. Several studies were conducted in order detect both germ-line somatic mutations linked development and, context, next generation sequencing technologies offer a pivotal resource for amount outputted information. We performed whole exome on...
Twenty patients affected by bilateral occipital cortical-subcortical calcification (BOC) are described, 19 (95%) had epilepsy. In 8 of 16 cases studied, intestinal biopsy revealed coeliac disease. Fourteen partial epilepsy with a relatively benign outcome, while 4 were severe form epilepsy, very frequent, drug-resistant, generalised and seizures mental deterioration. One patient single episode convulsive status epilepticus at four months age. The neurological examination was normal in all...
Background and purpose Late‐onset Pompe disease ( LOPD ) is a rare, multisystem disorder that well established to mainly impair skeletal muscle function. Systematic studies exploring brain functions in are lacking. The aim of this study was detect morphological functional alterations as neuropsychological impairment . Methods We studied 21 patients (10 male, mean age 49 ± 18.4 years) with defined diagnosis , divided into two groups: one pre‐symptomatic hyper CK emia no weakness the second...
To compare dual-energy CT (DECT) and MRI for assessing presence extent of traumatic bone marrow edema (BME) fracture line depiction in acute vertebral fractures.Eighty-eight consecutive patients who underwent dual-source DECT 3-T the spine were retrospectively analyzed. Five radiologists assessed all vertebrae BME identification lines on and, after 12 weeks, series. Additionally, image quality, noise, diagnostic confidence overall diagnosis assessed. Quantitative analysis numbers was...
Abstract OBJECTIVE: Brainstem compression caused by vascular abnormalities has rarely been reported in the literature. We describe five cases of large ectatic vertebral artery causing and distortion medulla oblongata with pyramidal tract signs low cranial nerve dysfunction. Microvascular decompression retracting anchoring it to dura treatment choice. METHODS: Five patients, four male one female, presented progressive myelopathic features lower dysfunction, especially dysphonia dysphagia....
Brain arteriovenous malformation (bAVM) is a congenital defect affecting brain microvasculature, characterized by direct shunt from arterioles to venules. Germline mutations in several genes related transforming growth factor beta (TGF-β)/BMP signaling are linked both sporadic and hereditary phenotypes. However, the low incidence of inherited cases makes genetic bases disease unclear. To increase this knowledge, we performed whole exome sequencing on five patients, DNA purified peripheral...