A5012186486- Traumatic Brain Injury Research
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Parkinson's Disease Mechanisms and Treatments
- Dementia and Cognitive Impairment Research
- Advanced MRI Techniques and Applications
- Neurological disorders and treatments
- Multiple Sclerosis Research Studies
- Stroke Rehabilitation and Recovery
- Psychosomatic Disorders and Their Treatments
- Cerebrovascular and Carotid Artery Diseases
- Olfactory and Sensory Function Studies
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Spatial Neglect and Hemispheric Dysfunction
- Migraine and Headache Studies
- Epilepsy research and treatment
- COVID-19 and Mental Health
- Autism Spectrum Disorder Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Musculoskeletal pain and rehabilitation
- Pain Management and Treatment
- Cardiac Arrest and Resuscitation
- Ultrasound and Hyperthermia Applications
- Transcranial Magnetic Stimulation Studies
Centro Neurolesi Bonino Pulejo
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
Istituto Oncologico Veneto
2022
Weatherford College
2020-2022
Creative Commons
2020-2021
Arcadis (Czechia)
2021
Committee on Publication Ethics
2019-2020
Delaware Division of Libraries
2020
Ministero della Salute
2020
In spite of the worldwide financial and research efforts made, pathophysiological mechanism at basis Alzheimer's disease (AD) is still poorly understood. Previous studies using electroencephalography (EEG) have focused on slowing oscillatory brain rhythms, coupled with complexity reduction corresponding time-series their enhanced compressibility. These analyses been typically carried out single channels. However, limited investigations possibility yielded by computational intelligence...
A complex network approach is combined with time dynamics in order to conduct a space–time analysis applicable longitudinal studies aimed characterize the progression of Alzheimer's disease (AD) individual patients. The reveals how patient-specific patterns are associated progression, also capturing widespread effect local disruptions. This study carried out on resting electroence phalography (EEGs) seven AD test repeated after three months' period. proposed methodology allows extract some...
Alzheimer's disease (AD) is a neurodegenerative disorder that causes loss of connections between neurons. The goal this paper to construct complex network model the brain-electrical activity, using high-density EEG (HD-EEG) recordings, and compare organization in AD, mild cognitive impaired (MCI), healthy control (CNT) subjects. HD-EEG 16 MCI, 12 CNT was recorded during an eye-closed resting state. permutation disalignment index (PDI) used describe dissimilarity signals connection matrices...
In this work, we introduce Permutation Disalignment Index (PDI) as a novel nonlinear, amplitude independent, robust to noise metric of coupling strength between time series, with the aim applying it electroencephalographic (EEG) signals recorded longitudinally from Alzheimer's Disease (AD) and Mild Cognitive Impaired (MCI) patients. The goal is indirectly estimate connectivity cortical areas, through quantification corresponding EEG signals, in order find possible matching disease's...
Several fMRI studies in migraine assessed resting state functional connectivity different networks suggesting that this neurological condition was associated with brain alteration. The aim of present study to explore the association between cognitive functions and cerebral connectivity, default mode network, patients without aura, during interictal episodic attack.Twenty-eight (14 14 aura) matched normal controls, were consecutively recruited. A battery standardized neuropsychological test...
Introduction: late-life depression is a well-known risk factor for future dementia. Increasing evidences also show link between cerebral hypoperfusion and neurodegeneration, although data on Transcranial Doppler ultrasonography (TCD)-derived measures in patients with "Vascular Depression" (VD) are lacking. The aim of this study was to assess correlate TCD parameters cognitive function severity subcortical ischemic vascular disease sample VD patients. Methods: 76 (mean age 72.5 ± 5.3 years;...
The differential diagnosis between radiation necrosis, tumor recurrence and progression is crucial for the evaluation of treatment response planning. appearance treatment-induced tissue necrosis on conventional Magnetic Resonance Imaging (MRI) similar to brain it could be difficult differentiate two entities follow-up MRI examinations. Dynamic Susceptibility Contrast-enhanced (DSC) Contrast-Enhanced (DCE) are perfusion techniques that use an exogenous, intravascular, non-diffusible...
Purpose: To determine the best predictor of lesion volume induced by magnetic resonance (MR)-guided focused ultrasound (MRgFUS) thalamotomy in patients with tremor-dominant symptoms Parkinson’s disease (PD) and essential tremor (ET) patients. Methods: Thirty-six neurological medication-refractory (n°19 PD; n°17 ET) were treated using a commercial MRgFUS brain system (Exablate Neuro 4000, Insightec) integrated 1.5 T MRI unit (Sigma HDxt; GE Medical System). Linear regression analysis was used...
BACKGROUND: Acquired brain injuries (ABI) represent neurological disorders that can arise after traumatic and non-traumatic events. In addition to the physical, emotional cognitive challenges patients face, these bring changes in life of patient his or her family. OBJECTIVE: This study aims understand how occurrence an ABI condition disrupt reshape family functioning by examining certain dimensions such as role family, gender age, which may have a major influence on dynamics. METHODS: We...
Background and purpose Late‐onset Pompe disease ( LOPD ) is a rare, multisystem disorder that well established to mainly impair skeletal muscle function. Systematic studies exploring brain functions in are lacking. The aim of this study was detect morphological functional alterations as neuropsychological impairment . Methods We studied 21 patients (10 male, mean age 49 ± 18.4 years) with defined diagnosis , divided into two groups: one pre‐symptomatic hyper CK emia no weakness the second...
Abstract Background Migraine is a common neurological disorder characterized by complex physiopathology. We assessed brain morphologic differences in migraine and the possible pathogenetic mechanism underlying this disease. Methods analyzed images of patients, 14 with aura (MwA) [the mean (SD) age was 42.36 (2.95) years (range, 37–47)] without (MwoA) 43.5 (3.25) 39–50)] during episodic attack compared health subjects balanced (HS) 42.5 (5.17) 34–51)]. All underwent Magnetic Resonance Imaging...
Biomarker-based differential diagnosis of the most common forms dementia is becoming increasingly important. Machine learning (ML) may be able to address this challenge. The aim study was develop and interpret a ML algorithm capable differentiating Alzheimer's dementia, frontotemporal with Lewy bodies cognitively normal control subjects based on sociodemographic, clinical, magnetic resonance imaging (MRI) variables. 506 from 5 databases were included. MRI images processed FreeSurfer, LPA,...
Aim Cognitive impairment is present in several neurodegenerative disorders. The clock‐drawing test (CDT) represents a useful screening instrument for assessing the evolution of cognitive decline. aim this study was to investigate sensitivity CDT monitoring and differentiating decline Alzheimer's dementia (AD), vascular (VaD), Parkinson's disease (PD). Methods This involved 139 patients, including 39 patients with PD mild impairment, 16 demented 21 VaD 17 VaD, 33 due AD, 13 probable AD. All...
Abstract The sleep allows many psychological processes, such as immune system activity, body metabolism and hormonal balance, emotional mental health, learning, mnemonic processes. lack of could undermine physical purposes, causing an alteration in cognitive functions or metabolic disorders. In our study, we have examined the irregular effects with overweight obesity risk children adults. sample was composed 199 subjects, which 71 adults, (29 males 42 females), 128 (73 55 females). We...
Parkinson’s Disease (PD) is a progressive neurodegenerative disorder affecting motor and cognitive functions, reducing the quality of life (QoL) for both patients caregivers. This study explored correlations between clinical psychological factors in early-stage PD their caregivers, focusing on disease burden caregiver stress. Nineteen caregivers were assessed. For patients, we evaluated severity (Hoehn Yahr), functions (Montreal Cognitive Assessment, MoCA), anxiety levels (Hamilton Rating...
Bariatric surgery is an effective treatment for obesity, promoting significant and lasting weight loss while improving health quality of life. The study examines the clinical organizational pathway patients undergoing it, assessing impact services on their well-being through status analysis. It also seeks to understand whether patient satisfaction during care process correlates with improved A total 50 severe obesity were included between July 2020 October 2022. evaluation was conducted...
Introduction In 2024, 11 European scientific societies/organizations and one patient advocacy association have defined a patient-centered biomarker-based diagnostic workflow for memory clinics evaluating neurocognitive disorders. Methods We tested the performance of an artificial intelligence (AI) tool applied to neuropsychological magnetic resonance imaging (MRI) assessment staging causal hypothesis, which are two recommended steps guiding next recommending optimal biomarkers be used...