- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Pituitary Gland Disorders and Treatments
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Meningioma and schwannoma management
- Health Systems, Economic Evaluations, Quality of Life
- Cerebrospinal fluid and hydrocephalus
- Brain Metastases and Treatment
- Craniofacial Disorders and Treatments
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Head and Neck Surgical Oncology
- Growth Hormone and Insulin-like Growth Factors
- Traumatic Brain Injury and Neurovascular Disturbances
- Adrenal and Paraganglionic Tumors
- Artificial Intelligence in Healthcare and Education
- Cleft Lip and Palate Research
- Fetal and Pediatric Neurological Disorders
- Prion Diseases and Protein Misfolding
- Spinal Dysraphism and Malformations
- Intracerebral and Subarachnoid Hemorrhage Research
- dental development and anomalies
- Neurological and metabolic disorders
- Bone Tumor Diagnosis and Treatments
Università Cattolica del Sacro Cuore
2014-2025
Agostino Gemelli University Polyclinic
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2025
University of Udine
2020
Research Institute of Radiology
2015
Istituto di Ortofonologia
2015
University of Zurich
2015
Catholic University of America
2002-2014
Sapienza University of Rome
1985-2011
University Radiology
2011
To report the clinical and immunological characteristics of 22 new patients with glial fibrillar acidic protein (GFAP) autoantibodies.From January 2012 to March 2017, we recruited 451 suspected neurological autoimmune disease at Catholic University Rome. Patients' serum cerebrospinal fluid (CSF) samples were tested for neural autoantibodies by immunohistochemistry on mouse rat brain sections, cell-based assays (CBA) immunoblot. GFAP detected their specificity confirmed CBA using cells...
The survival benefit in maximizing resection glioblastomas (GBMs) has been demonstrated by numerous studies. true limit of infiltration GBMs an overwhelming obstacle, and several technological advances have introduced to improve the identification residual tumors.To evaluate whether integration 5-aminolevulinic acid (5-ALA) with microbubble contrast-enhanced ultrasound (CEUS) improves tumor impact on extent (EOR), overall (OS), progression-free (PFS).A total 230 GBM procedures were...
Hydrocephalus affects 7% to 10% of patients with Chiari I malformation (CIM). It can be successfully treated by endoscopic third ventriculostomy (ETV), possibly improving related CIM and syringomyelia.To confirm the effectiveness ETV in management Chiari-related hydrocephalus symptoms estimate posterior cranial fossa volume (PCFV) find possible reasons for success or failure ETV.Fifteen (11 children 4 adults) underwent associated (syringomyelia was present 6 patients). Preoperative PCFV,...
La finalità del nostro lavoro è di valutare le caratteristiche risonanza magnetica (RM) tipiche dei tumori parotidei maligni e benigni. Questo studio retrospettivo si basa sulla valutazione esami RM pre-chirurgici 94 pazienti con parotidei. I risultati istologici erano disponibili in tutti i casi; abbiamo analizzato 69 lesioni benigne (73%) 25 maligne (27%): 44 adenomi pleomorfi, 18 Warthin, 7 benigni diverso istotipo, 6 carcinomi squamocellulari, 3 ex-adenomi 2 mucoepidermoidi, 1 tumore...
Neuroimaging studies often lack reproducibility, one of the cardinal features scientific method. Multisite collaboration initiatives increase sample size and limit methodological flexibility, therefore providing foundation for increased statistical power generalizable results. However, multisite collaborative are inherently limited by hardware, software, pulse sequence design heterogeneities both clinical preclinical MRI scanners benchmark acquisition protocols, data analysis, sharing. We...
Biomarker-based differential diagnosis of the most common forms dementia is becoming increasingly important. Machine learning (ML) may be able to address this challenge. The aim study was develop and interpret a ML algorithm capable differentiating Alzheimer's dementia, frontotemporal with Lewy bodies cognitively normal control subjects based on sociodemographic, clinical, magnetic resonance imaging (MRI) variables. 506 from 5 databases were included. MRI images processed FreeSurfer, LPA,...
Abstract Introduction Cytokine and chemokines have been recognized to be involved in the progression prognosis of pituitary adenoma/neuroendocrine tumors (PAs/PitNETs), also known as adenomas. We aim investigate expression cytokine chemokine PAs/PitNETs, their association with PAs/PitNETs clinical biological behavior. Patients methods A prospective monocenter study was performed on 16 patients diagnosed for PAs/PitNETs. were detected freshly collected samples. Tumor infiltering immune cells...
To quantify inner ear fluid changes in patients with audiovestibular deficits by measuring signal intensity values; to correlate the values of structures and audio-vestibular impairment severity. 26 unilateral vestibulocochlear underwent hearing vestibular assessments were categorised into severity classes using audiological deficit scores. Normalised extracted from 3D-T2-WI-MRI scans (nT2mean, nT2Max, nT2min) ratios calculated unaffected as a reference. Asymmetry nT2Max nT2mean volumetric...