A5008464627- Glioma Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Musculoskeletal pain and rehabilitation
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Epilepsy research and treatment
- Cervical and Thoracic Myelopathy
- Pelvic and Acetabular Injuries
- Anesthesia and Pain Management
- MRI in cancer diagnosis
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Trigeminal Neuralgia and Treatments
- Pain Management and Treatment
- Transplantation: Methods and Outcomes
- Head and Neck Surgical Oncology
- Organ and Tissue Transplantation Research
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Neural dynamics and brain function
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2025
Agostino Gemelli University Polyclinic
2016-2024
Università Cattolica del Sacro Cuore
2014-2020
Policlinico San Matteo Fondazione
2020
University of Udine
2020
Université Claude Bernard Lyon 1
2020
Unité de Nutrition Humaine
2016
The survival benefit in maximizing resection glioblastomas (GBMs) has been demonstrated by numerous studies. true limit of infiltration GBMs an overwhelming obstacle, and several technological advances have introduced to improve the identification residual tumors.To evaluate whether integration 5-aminolevulinic acid (5-ALA) with microbubble contrast-enhanced ultrasound (CEUS) improves tumor impact on extent (EOR), overall (OS), progression-free (PFS).A total 230 GBM procedures were...
OBJECTIVE Intraoperative MRI (iMRI) is the gold-standard technique for intraoperative evaluation of extent resection in brain tumor surgery. Unfortunately, it currently available at only a few neurosurgical centers. A commercially software, Virtual iMRI Cranial, provides an elastic fusion between preoperative and CT (iCT). The aim this study was to evaluate accuracy software determining presence residual tumor. METHODS performed patients who underwent iCT after intracranial resection....
Background/Objectives: Lumbar disc herniation, a complex challenge in spinal health, significantly impacts individuals across diverse age groups. This article delves into the intricacies of this condition, emphasising pivotal role anatomical considerations its understanding and management. Additionally, lumbar discectomy might be considered an “easy” surgery; nevertheless, it carries significant risks. The aim study was to present groundbreaking “three-step approach” with some insight...
Abstract Surgical management of Diffuse Low-Grade Gliomas (DLGGs) has radically changed in the last 20 years. Awake surgery (AS) combination with Direct Electrical Stimulation (DES) and real-time neuropsychological testing (RTNT) permits continuous intraoperative feedback, thus allowing to increase extent resection (EOR). The aim this study was evaluate impact technological advancements integration multidisciplinary techniques on EOR. Two hundred eighty-eight patients affected by DLGG were...
Percutaneous pedicle screw (PPS) placement is a key step in several minimally invasive spinal surgery (MISS) procedures. Traditional technique for PPS makes use of C-arm fluoroscopy assistance (FA). More recently, newer intraoperative imaging techniques have been developed PPS, including CT-guided navigation (CTNav). The aim this study was to compare FA and CTNav with regard accuracy, complications, radiation dosage.A total 192 patients degenerative lumbar spondylolisthesis canal stenosis...
Background/Objectives: Degenerative lumbar spine conditions are a major cause of disability, particularly in elderly patients or those with comorbidities. Surgical treatment often combines decompression and stabilization to address pain instability. Pedicle screws the gold standard for but pose challenges compromised bone quality. Interspinous devices have emerged as less invasive alternative, comparative studies limited. This study aimed compare clinical surgical outcomes using pedicle...
Background/Objectives: Lumbar disk herniation (LDH) significantly affects quality of life due to lower back and radiating leg pain. Surgical intervention, such as discectomy, is effective for symptom relief when conservative measures fail; however, psychological factors like anxiety, depression, maladaptive coping strategies may negatively impact surgical outcomes. This study aims assess the role preoperative evaluations in predicting postoperative recovery identify key functional predictors...
Background/Objectives: Degenerative lumbar spine conditions are a major cause of disability, particularly in elderly patients or those with comorbidities. Surgical treatment often combines decompression and stabilization to address pain instability. Pedicle screws the gold standard for but pose challenges compromised bone quality. Interspinous devices have emerged as less invasive alternative, comparative studies limited. This study aimed compare clinical surgical outcomes using pedicle...
Abstract Background Inferior Fronto-Occipital Fascicle (IFOF) is a multitasking connection bundle essential for communication and high level mentalization. The aim of the present study was to quantitatively assess its radiological-anatomical-morphometric modifications according different brain tumor histotype. Methods A retrospective multicentric Italian conducted. IFOF reconstructions were calculated both hemispheres each patient diagnosed with Glioblastoma (GBM), Low Grade Glioma (LGG),...
Abstract Background Minimally invasive spine surgery is a field of active and intense research. Image-guided percutaneous pedicle screw (PPS) placement valid alternative to the standard free-hand technique, thanks technological advancements that provide potential improvement in accuracy safety. Herein, we describe clinical results surgical technique exploiting integration neuronavigation intraoperative neurophysiological monitoring (IONM) for minimally PPS. Materials Methods An...
Study design: Prospective study. Objective: To evaluate the influence of preoperatively assessed psychosomatic traits on postoperative pain, disability, and quality life outcomes. Summary background data: Anterior cervical discectomy fusion (ACDF) is a widely employed surgical procedure for treating spondylosis. Despite its effectiveness, various studies have reported non-success rates in terms alleviating disability pain. Psychological factors become increasingly recognized as critical...
This study aimed to evaluate the efficacy of mindfulness therapy compared traditional physiotherapy and usual care in alleviating postoperative pain improving functional outcomes patients undergoing lumbar spine surgery during COVID-19 pandemic.
Background/Objectives: Lumbar decompression surgery for degenerative lumbar stenosis is an intervention which addresses a condition affecting many patients. This article presents meticulous three-phase surgical approach, derived from our clinical experiences and intertwining anatomical insights, offering nuanced perspective tailored the educational needs of young spinal surgeons. Methods: Six hundred eighty-seven patients who underwent at single institution were included in present study. A...
Increasing the extent of resection (EOR) is considered a main goal in high grade glioma (HGG) surgery. Significant advancements have been recently made to assist surgery: namely use 5-aminolevulinic acid (5ALA) and application contrast-enhanced ultrasound (CEUS) embody two most introduced tools neuro-oncology field. A combined approach including techniques has suggested literature. Our primary aim identify which conditions CEUS final survey real impact 5-ALA guided context assess...
Neuronavigation of preoperative MRI is limited by several errors. Intraoperative ultrasound (iUS) with navigated probes that provide automatic superposition pre-operative and iUS three-dimensional reconstruction may overcome some these limitations. Aim the present study to verify accuracy an - fusion algorithm improve MR-based neuronavigation accuracy.An using Linear Correlation Combination (LC2)-based similarity metric has been retrospectively evaluated for twelve datasets acquired in...