A5065833399- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Distributed and Parallel Computing Systems
- Glioma Diagnosis and Treatment
- Nutrition and Health in Aging
- Sarcoma Diagnosis and Treatment
- Scientific Computing and Data Management
- Pancreatic and Hepatic Oncology Research
- T-cell and Retrovirus Studies
- Parallel Computing and Optimization Techniques
- Ethics and Legal Issues in Pediatric Healthcare
- Genetics and Neurodevelopmental Disorders
- Vitamin C and Antioxidants Research
- Spinal Hematomas and Complications
- Reproductive System and Pregnancy
- Chromatin Remodeling and Cancer
- Management of metastatic bone disease
- Viral-associated cancers and disorders
- Neutropenia and Cancer Infections
- Innovations in Medical Education
- Global Health and Surgery
- Palliative and Oncologic Care
- Cancer-related cognitive impairment studies
University of Victoria
2024
Instituto de Medicina Integral Professor Fernando Figueira
2009-2022
Real Hospital Português
2017-2020
Istituto Nazionale di Fisica Nucleare, Sezione di Milano
2018
Instituto de Tecnologia de Pernambuco
2002-2017
Brazilian Medical Association
2012-2017
St. Jude Children's Research Hospital
2006-2015
Universidad Francisco Marroquín
2015
Instituto Medicina Integrativa (Portugal)
2012
Mahak Hospital and Rehabilitation Complex
2012
Abstract Many children with cancer in low‐ and middle‐income countries are treated hospitals lacking key infrastructure, including diagnostic capabilities, imaging modalities, treatment components, supportive care, personnel. Childhood regimens adapted to local conditions provide an opportunity cure as many possible the available resources, while working improve services care. This paper from Adapted Treatment Regimens Working Group of Pediatric Oncology Developing Countries committee...
MicroRNAs (miRNAs) play a critical role on biological and cellular processes; the search for functional markers may be of importance differential diagnosis, prognosis, development new therapeutic regimens. In this context, we evaluated bone marrow miRNA profile Brazilian children exhibiting T- or B-cell acute lymphoblastic leukemia (T-ALL B-ALL), using massive parallel sequencing, HiSeq 2500 platform (Illumina). The expression analysis was conducted considering leave-one-out approach FDR ≤...
Purpose To investigate the relationship between survival and malnutrition at time of diagnosis among children treated for cancer in two developing countries. Patients Methods We studied 443 1995 1998 centers San Salvador, El Recife, Brazil. Median age was 4.9 years; 283 had leukemia 160 solid tumors. Z-scores were calculated weight (WAZ), height (HAZ), (WHZ) diagnosis. Z scores <−2 indicated malnutrition. also stratified by low-risk disease (solid tumors: stage I, II, or localized; acute...
Objective: The aim of this study was to evaluate the influence low-level laser therapy (LLLT) on prevention and treatment oral mucositis (OM) in pediatric cancer patients taking methotrexate. Background data: OM is a very common, potentially severe side effect, caused by with radiotherapy chemotherapy for cancer. Methods: Forty acute lymphoblastic leukemia, who received high doses methotrexate, were distributed into two groups. Group A (Preventive Group) composed preventive (red-subgroup A1...
The objectives of this study were to describe the interval between symptom onset and diagnosis acute leukemia, assess risk factors for delayed diagnosis, its effect on early morbid-mortality event-free survival (EFS). Records children aged 1 month 18 years diagnosed with leukemia reviewed clinical, demographic, health care provider factors, time diagnosis. Of 288 patients diagnosed, 55% had a delay in median was 31 days. There significant associations diagnostic distance from tertiary...
Accurate diagnosis is critical for optimal management of pediatric cancer. Pathologists with experience in oncology are short supply the developing world. Telepathology increasingly used consultations but its overall contribution to diagnostic accuracy unknown.We developed a strategy provide focused training cancer and telepathology support pathologists After period, we compared trainee's diagnoses those an experienced pathologist. We next effectiveness static versus dynamic review 127...
A gap in childhood cancer outcomes remains between developed and developing countries. Persistence of this may be caused by financial, social, or educational disparities. Twinning distance learning initiatives improve such Integrating telemedicine into pediatric oncology twinning programs enhances education facilitates patient-centered capacity building.We performed an analysis Web-based meetings held from August 2005 through July 2009 the International Outreach Program at St. Jude...
Pediatric Hodgkin lymphoma (HL) has a cure rate of more than 80% in high-income countries (HIC). However, the world's children live low-income (LIC), where is often much lower.We compared outcome HL 371 patients treated at two pediatric oncology centers US to that 62 one center Recife, Brazil (IMIP) determine whether same treatment strategy should be used both and LIC. The logrank test was compare event-free overall survival.The percentages with unfavorable disease each were similar (P =...
Summary Introduction Lumbar punctures ( LP ) in patients presenting thrombocytopenia are linked to the possibility of bleeding and spinal hematomas. The minimum platelet count required for safe performance procedures is still under discussion. Children with some oncology diseases require routinely lumbar punctures; such often present thrombocytopenia, making this group an ideal population study association between puncture thrombocytopenic complications. Objectives To determine children...
Abstract Hybrid-electric power is an appealing technology for multirotor platforms due to its ability enhance the range of vehicle while providing low emissions and precise thrust control required stability. The development a utilizing hybrid propulsion essential step CfAR as it will be basis research on this in flight. designed multirotor, MIMIQ (Modular Inertia Matching Quadcopter), 32kg quadcopter with motor-to-motor diameter 2.7m which require total 3,700W hover. This demand primarily...
Olanzapine is a tricyclic neuroleptic agent that due to structural similarities was expected be safe alternative clozapine, which has 0.5-2 % risk of agranulocytosis. So far, only rare cases leukocytopenia and thrombocytopenia have become known. In the association "Drug Safety in Psychiatry", made up 25 German psychiatric hospitals, two olanzapine-induced neutropenia occurred patients with chronic schizophrenia. The adverse drug reaction noticed 17 days after first intake olanzapine case 1...
The prevalence of malnutrition upon diagnosis, together with reduced food intake secondary to disease and treatment, make the periodic assessment nutritional status (including antioxidant nutrients) considerable importance follow up patients cancer.Assess frequency inadequate vitamin C levels among children adolescents cancer at beginning treatment determine associated factors.A cross-sectional study was carried out 30 under 18 years. Nutritional assessed using laboratory methods...
RESUMO: Leucemia linfóide Aguda (LLA), é o tipo mais comum de câncer infantil, constituindo cerca um terço todas as neoplasias malignas da criança. A incidência LLA em crianças nos Estados Unidos aproximadamente 3,4 casos por 100.000 menores 15 anos idade. Até a metade do século passado, leucemias eram consideras universalmene, uma doença fatal. O desenvolvimento combinações terapêuticas, utilizando diversas drogas citotóxicas com ou sem transplante medula óssea, tem aumentado percentual...
Individualized nutritional support is important to pediatric cancer patients and should be integrated the overall treatment of these patients.Analyze status submitted enteral nutrition (EN) assess adequacy this form nutrition.A case series study was carried out at Pediatric Oncology Unit Institute Integrative Medicine Professor Fernando Figueira (IMIP, Brazil, Recife-PE) between January December 2009. Clinical anthropometric data were obtained from medical charts follow-up charts. Z scores...
Background This study investigated the impact of posterior fossa tumors and their respective treatments, clinical sociodemographic variables, on intelligence quotient (IQ) Brazilian children. Methods Twenty patients took part in study, which 13 were diagnosed with astrocytoma (average age at evaluation 10.2 y) 7 medulloblastoma 9.2 y). The first subgroup was submitted exclusively to tumor resection surgery second underwent surgery, chemotherapy (Vincristine, Cisplatine, Carmustine),...