A5003526542- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- Cancer Mechanisms and Therapy
- Immune Cell Function and Interaction
- Dermatology and Skin Diseases
- Protein Kinase Regulation and GTPase Signaling
- Takotsubo Cardiomyopathy and Associated Phenomena
- Ferroptosis and cancer prognosis
- Aldose Reductase and Taurine
- Acupuncture Treatment Research Studies
- Alcohol Consumption and Health Effects
- Axon Guidance and Neuronal Signaling
- Advanced Glycation End Products research
- Acne and Rosacea Treatments and Effects
- Anesthesia and Neurotoxicity Research
- Genomics, phytochemicals, and oxidative stress
- Heart Rate Variability and Autonomic Control
- Neural dynamics and brain function
- Receptor Mechanisms and Signaling
- Dermatologic Treatments and Research
- Cancer Immunotherapy and Biomarkers
- Alzheimer's disease research and treatments
- Noise Effects and Management
Guangzhou University of Chinese Medicine
2017-2022
Sinisan (SNS) consists of four kinds herbs, which is the core antidepressant prescription widely used in traditional Chinese medicine clinic treatment for depression induced by early life stress. However, role and precise mechanism SNS have not yet been elucidated.This study aimed to investigate on regulating mitochondrial function improve hippocampal synaptic plasticity.90 Sprague-Dawley (SD) rats male pups Post-Natal Day (PND) 0 were randomly divided into Control group (ddH20), Model...
Major depressive disorder (MDD) is an emotional condition that interferes with sufferers' work and daily life. Numerous studies have found miRNAs play a significant role in the development of MDD can be utilized as biomarker for its diagnosis therapy. However, there been few on nerve-immunity interaction treatment brains MMD patients.The performed microarray data. We analyzed differences (GSE58105, GSE81152, GSE152267, GSE182194) mRNA (GSE19738, GSE32280, GSE44593, GSE53987, GSE98793)...
Background . Doxorubicin (DOX) is a commonly used chemotherapeutic drug but limited in clinical applications by its cardiotoxicity. Neiguan acupoint (PC6) well‐recognized for the treatment of cardiothoracic disease. However, whether acupuncture at PC6 could be effective preventing DOX‐induced cardiotoxicity still unknown. Methods A set experiments were performed with myocardial cells, wild type, inducible nitric oxide synthase knockout (iNOS‐/‐), and myocardial‐specific ablation arginase 2...
The dorsal raphe nucleus (DRN) is a major source of serotonin in the central nervous system, which closely related to depression-like behaviors and modulated by local GABAergic interneurons. Although neurons are known be activated struggling behavior tail suspension test (TST), exact electrophysiological characteristics still unclear. Here, we combined vivo electrode recording behavioral explore mice neuron electrophysiology DRN during TST observed that gamma oscillation was despair-like...
Neuroinflammation is considered as one of the crucial pathogenesis in promoting neurodegenerative progress Alzheimer’s disease (AD). As complementary and alternative therapy, electroacupuncture (EA) stimulation has been widely used clinical practice for anti-inflammation. However, whether EA promotes cognitive deficits resulting from neuroinflammation AD remains unclear. In this study, presenilin 1 2 conditional double knockout (PS cDKO) mice, exhibited a series AD-like pathology, robust...
The aim of this study was to evaluate the risk factors depressive symptoms in occupational noise-induced hearing loss (NIHL) patients.A total 106 patients were divided into (ONHLPD) and without (non-ONHLPD) according Self-rating Depression Scale. Questionnaires laboratory data collected analyzed. Data analyzed with independent t-test, Wilcoxon test, Pearson correlation analysis multiple linear regression models.The prevalence 53.8% NIHL patients. In ONHLPD, duration loss, level serum...
Ovarian cancer (OC) is the second leading cause of death in gynecological cancer. Multiple study have shown that efficacy tumor immunotherapy related to immune cell infiltration (ICI). However, so far, Immune landscape microenvironment (TME) OC has not been elucidated. In this study, We organized transcriptome data Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases, evaluated patient's TME information, constructed ICI scores predict clinical benefits patients undergoing...
Gastric carcinoma (GC) is a kind of digestive tract tumor that highly malignant and has very poor prognosis. Although both Astragalus mongholicus (AM, huáng qí) Curcuma phaeocaulis Valeton (CPV, é zhú) can slow the onset progression GC, mechanism by which AM-CPV works in treatment GC uncertain.The traditional Chinese medicine network databases TCMSP, TCMID, ETCM were used to identify key functional components associated targets AM CPV. To establish theoretical foundation, development gastric...
Rationale: Rosacea is an irritating disease that affects patients' health and life quality. The current treatments for rosacea have limited efficacy are generally not satisfying most patients. This report presents a patient diagnosed with who was treated acupuncture to satisfactory effect. Laser Doppler used measure the local blood perfusion of nose before, during, after treatment. Dermatology Life Quality Index (DLQI) impact on quality patient's life. Patient concerns: A 52-year-old woman...