A5100340545- Liver Disease Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Thyroid Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Ultrasound and Cavitation Phenomena
- Tracheal and airway disorders
- Peptidase Inhibition and Analysis
- Monoclonal and Polyclonal Antibodies Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Urology and Nephrology Studies
- Gastric Cancer Management and Outcomes
- RNA modifications and cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Liver Disease and Transplantation
- Cancer, Hypoxia, and Metabolism
Henan Cancer Hospital
2021-2025
Zhengzhou University
2017-2025
Capital Medical University
2017-2025
Huazhong University of Science and Technology
2016-2025
Guangzhou Institute of Dermatology
2022-2025
Chongqing Medical University
2007-2025
Shanxi Medical University
2013-2025
Sichuan University
2013-2025
West China Hospital of Sichuan University
2011-2025
Union Hospital
2016-2025
Catheter-based pulmonary artery denervation (PADN) has achieved promising outcomes to treat hypertension (PH). We herein present stereotactic body radiotherapy (SBRT) as a novel noninvasive approach for PADN. A single fraction of 15 Gy, 20 Gy or 25 was delivered PADN in thromboxane A2 (TxA2) - induced acute PH swine model. demonstrated that by 20-Gy SBRT reduced mean (PA) pressure during the TxA2 challenge. All dosages led deeper area compared with radiofrequency ablation (RFA) and...
Purpose: We propose a systematic methodology to quantify incidentally identified pulmonary nodules based on observed radiological traits (semantics) quantified point scale and machine-learning method using these data predict cancer status.Experimental Design: investigated 172 patients who had low-dose CT images, with 102 70 grouped into training validation cohorts, respectively. On the 24 were systematically scored linear classifier was built relate malignant status. The model formed both...
To evaluate the diagnostic accuracy of computed tomography (CT)-guided percutaneous lung biopsy for solitary pulmonary nodules. Three hundred and eleven patients (211 males 100 females), with a mean age 59.6 years (range, 19–87 years), who were diagnosed nodules underwent CT-guided transthoracic needle between January 2008 2014 reviewed. All confirmed by surgery or clinical course. The overall incidence complications calculated, factors influencing these statistically evaluated compared....
Background: Nonalcoholic fatty liver disease (NAFLD) is the most frequent cause of chronic diseases worldwide. At present, there are no effective pharmacological therapies for NAFLD except lifestyle intervention-mediated weight loss. Atractylenolide III (ATL III), major bioactive component found in Atractylode smacrocephala Koidz, has been shown to exert anti-oxidant, anti-tumor, anti-allergic response, anti-bacterial effects and cognitive protection. Here we investigate therapeutic...
Viruses evade the innate immune response by suppressing production or activity of cytokines such as type I interferons (IFNs). Here we report discovery a mechanism which SARS-CoV-2 virus coopts an intrinsic cellular machinery to suppress key immunostimulatory cytokine IFN-β. We reveal that encoded nonstructural protein 2 (NSP2) directly interacts with GIGYF2 protein. This interaction enhances binding mRNA cap-binding 4EHP, thereby repressing translation Ifnb1 mRNA. Depletion 4EHP...
Background and Aims: The intratumoral microbiome has been reported to regulate the development progression of cancers. We aimed characterize microbial heterogeneity (IMH) establish microbiome-based molecular subtyping HBV-related HCC elucidate correlation between IMH tumorigenesis. Approach Results: A case-control study was designed investigate landscape characteristic signatures tissues adopting metagenomics next-generation sequencing. Microbiome-based established by nonmetric...
Background US shear-wave elastography (SWE) and vibration-controlled transient (VCTE) enable assessment of liver stiffness, an indicator fibrosis severity. However, limited reproducibility data restrict their use in clinical trials. Purpose To estimate SWE VCTE measurement variability nonalcoholic fatty disease (NAFLD) within across systems to support trial diagnostic enrichment interpretation longitudinal stiffness. Materials Methods This prospective, observational, cross-sectional study...
ABSTRACT Purpose To validate an algorithm that uses delivery date and diagnosis codes to define gestational age at birth in electronic health plan databases. Methods Using data from 225 384 live born deliveries women aged 15–45 years 2001–2007 within eight of the 11 plans participating Medication Exposure Pregnancy Risk Evaluation Program, we compared (1) algorithm‐derived versus “gold‐standard” obtained infant certificate file (2) prenatal exposure status two antidepressants (fluoxetine...
Akt mediates postnatal angiogenesis through eNOS signaling.