A5063897714- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Vibrio bacteria research studies
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Probiotics and Fermented Foods
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
Utrecht University
2020-2024
Plasmid-mediated antimicrobial resistance is a major contributor to the spread of genes within bacterial communities. Successful plasmid depends upon balance between fitness effects on host and rates horizontal transmission. While these key parameters are readily quantified in vitro , influence interactions with other microbiome members largely unknown. Here, we investigated three genera lactic acid bacteria (LAB) derived from chicken gastrointestinal an epidemic narrow-range ESBL plasmid,...
The emergence of carbapenemase-producing Enterobacteriaceae (CPE) is a threat to public health, because their resistance clinically important carbapenem antibiotics. CPE in meat-producing animals particularly worrying consumption meat contaminated with resistant bacteria comparable CPE, such as extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae, contributed colonization humans worldwide. Currently, no data on the transmission livestock available. We performed experiment...
Abstract The emergence of carbapenemase-producing Enterobacteriaceae (CPE) is a threat to public health, because their resistance clinically important carbapenem antibiotics. CPE in meat-producing animals particularly worrying consumption meat contaminated with resistant bacteria similar CPE, such as extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae, contributed colonization humans worldwide. Currently, no data on the transmission livestock available. We performed...
Understanding under which conditions conjugative plasmids encoding antibiotic resistance can invade bacterial communities in the gut is of particular interest to combat spread within and between animals humans. We extended a one-compartment model conjugation two-compartment model, analyse how differences plasmid dynamics lumen at wall affect invasion plasmids. compared scenarios with one two compartments, different migration rates population dynamics. focused on effect attachment detachment...