A5022821516- Anesthesia and Sedative Agents
- Veterinary Pharmacology and Anesthesia
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Electrolyte and hormonal disorders
- Veterinary Equine Medical Research
- Pain Mechanisms and Treatments
- Intensive Care Unit Cognitive Disorders
Universidade de São Paulo
2011-2022
Universidade Estadual Paulista (Unesp)
2006
This study compared pressure and thermal thresholds after administration of three opioids in eight cats. Pressure stimulation was performed via a bracelet taped around the forearm. Three ball‐bearings were advanced against forearm by inflation modified blood bladder. cuff recorded at end point (leg shake head turn). Thermal threshold tested as previously reported using heated probe held thorax [ Dixon et al . (2002) Research Veterinary Science , 72 205]. After baseline recordings, each cat...
To determine whether dexmedetomidine aggravates hemodynamic, metabolic variables, inflammatory markers, and microcirculation in experimental septic shock.Twenty-four pigs randomized into: Sham group (n = 8), received saline; Shock an intravenous infusion of Escherichia coli O55 (3 × 109 cells/mL, 0.75 mL/kg, 1 hour); Dex-Shock bacteria (bolus 0.5 mcg/kg followed by 0.7 mcg/kg/h). Fluid therapy and/ornorepinephrine were administered to maintain a mean arterial pressure > 65 mmHg. Hemodynamic,...
The use of dexmedetomidine to achieve sedation, analgesia and mechanical ventilation has increased in critically ill patients, although little is known about its effects septic shock. aim this study was assess hemodynamic, metabolic inflammatory a pig model