A5007465048- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Ionic liquids properties and applications
- Traumatic Ocular and Foreign Body Injuries
- Intraocular Surgery and Lenses
- Extracellular vesicles in disease
- Ocular Infections and Treatments
- Epigenetics and DNA Methylation
- Extraction and Separation Processes
- RNA modifications and cancer
- Retinal Imaging and Analysis
- Facial Trauma and Fracture Management
- Folate and B Vitamins Research
- Retinal and Optic Conditions
- Mesoporous Materials and Catalysis
- Reproductive System and Pregnancy
- MicroRNA in disease regulation
Shandong Eye Hospital
2020-2023
Shandong First Medical University
2020-2023
Qingdao University
2019-2021
Affiliated Hospital of Qingdao University
2020
Abstract Immune rejection and side effects of long‐term administration immunosuppressants are the two major obstacles to allograft acceptance tolerance. The immunosuppressive extracellular vesicles (EVs)‐based approach has been proven be effective in treating autoimmune/inflammatory disorders. Herein, anti‐rejection advantage exosomes (Rapa‐Exo) from rapamycin‐conditioned myeloid‐derived suppressor cells (MDSCs) over (Exo‐Nor) untreated MDSCs is shown. exosomal small RNA sequencing...
Abstract Background Keratoconus (KC) is a common, degenerative disorder of the cornea, and genetic factors play key role in its development. However, etiology KC still unclear. This study used family twins as material, using, for first time, multi-omics analysis, to systematically display changes candidate patients at DNA, RNA, protein levels. These can evaluate pathogenic depth lock onto targets. Results The this presented classic phenotypes, clear diagnoses, complete case data, clinical...
Abstract Background To compare the postoperative complications and visual outcomes of big‐bubble deep anterior lamellar keratoplasty (BB‐DALK) penetrating (PK) for fungal keratitis (FK). Methods This retrospective study included 94 cases BB‐DALK FK 161 PK from a tertiary ophthalmology care centre. Results The most common pathogens were Fusarium ( n = 84, 32.9%) Aspergillus 67, 26.3%). recurrence rates after 3.2 5%, respectively p 0.723). follow‐up duration was 31.9 ± 15.8 months in group...
To analyze the clinical characteristics and visual prognoses of patients with ocular trauma treated in Shandong Eye Hospital. The inpatient data eye injuries hospitalized our institution from January 2014 to December 2018 were retrospectively reviewed, including demographic information, types trauma, causes injury, treatment, initial final acuities. A total 1,425 (1,622 eyes), aged 39.5 ± 18.5 years, included. ratio male female was 5.3 : 1. Of mechanical injuries, there 490 (34.4%)...
To explore the primary indications, direct causes and graft survival of short-term repeat keratoplasty.An analytical cross-sectional study.The indications for keratoplasty were infectious keratitis (67.9%) immune keratopathy (12.8%). The failure ulcer (43.6%) recurrence (30.8%). Pre-operative hypopyon (P = 0.017, HR 1.757) use decellularized porcine corneas as grafts 0.005, 2.690) independent risk factors failure. Kaplan-Meier analysis revealed that 1-year rate 88 was 85.2%, 5-year 79.2%....
Background: Copy number variations (CNVs) may explain some of the missing heritability not identified in genome-wide association studies (GWASs).