- Neuroscience and Neural Engineering
- EEG and Brain-Computer Interfaces
- Advanced Radiotherapy Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiovascular and Diving-Related Complications
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Radiation Dose and Imaging
- Healthcare Policy and Management
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Attention Deficit Hyperactivity Disorder
- Retinal Development and Disorders
- Cardiac Valve Diseases and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Infective Endocarditis Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Intracranial Aneurysms: Treatment and Complications
- Cancer Diagnosis and Treatment
- Management of metastatic bone disease
National Institute for Health and Care Excellence
2019-2022
King's College London
2020
Aims PFO closure is a percutaneous intervention, which aims to reduce risk of recurrent stroke by preventing paradoxical embolism. The objective this study was measure procedural safety and longer-term effectiveness in UK setting. Methods results Prospective registry data from patients with cryptogenic eligible for were collected up 2 years linked routine sources additional follow-up. Outcomes interest included success rate, health related quality life, death neurological event rates. A...
Abstract Aims Non-valvular atrial fibrillation (AF) greatly increases the risk of ischaemic stroke. For people with contraindications to oral anticoagulation, left appendage occlusion (LAAO) provides a non-pharmacological management alternative. The aim this study was measure procedural safety and longer-term effectiveness LAAO for AF in UK setting. Methods results This prospective, single-armed registry patients whom anticoagulation unsuitable. Registry data were collected between October...
Aims Percutaneous mitral valve leaflet repair is a treatment option for some people with severe regurgitation whom conventional surgery clinically inappropriate. This study aimed to determine the safety, efficacy, and costs of percutaneous repair, using MitraClip device in UK setting. Methods results was prospective, single-armed registry follow-up 2 years that reported range procedural, clinical patient-orientated outcomes. Registry data were linked routine sources allow more comprehensive...
Background Retinitis pigmentosa is an incurable, degenerative retinal condition causing progressive sight loss, significantly affecting patients’ quality of life. The Argus II Retinal Prosthesis a surgically implanted medical device that delivers electrical stimulation to the retina. It intended produce form artificial vision for blind people with severe-to-profound retinitis by stimulating remaining viable cells induce visual perception. This study has been initiated National Health Service...
Objectives The UK MitraClip registry was commissioned by National Health Service (NHS) England to assess real-world outcomes from percutaneous mitral valve repair for regurgitation using a new technology, MitraClip. This study aimed determine longitudinal patient linking routine datasets: Hospital Episode Statistics (HES) Admitted Patient Care (APC) and Office of Statistics. Methods Two methods linkage were compared, identifiable (NHS number, date birth, postcode, gender) non-identifiable...
<sec> <title>BACKGROUND</title> Retinitis pigmentosa is an incurable, degenerative retinal condition causing progressive sight loss, significantly affecting patients’ quality of life. The Argus II Retinal Prosthesis a surgically implanted medical device that delivers electrical stimulation to the retina. It intended produce form artificial vision for blind people with severe-to-profound retinitis by stimulating remaining viable cells induce visual perception. This study has been initiated...