A5026480564- Mechanical Circulatory Support Devices
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac Ischemia and Reperfusion
- Cardiac pacing and defibrillation studies
- Aortic Disease and Treatment Approaches
- Hemodynamic Monitoring and Therapy
- Acute Kidney Injury Research
- Cardiac Arrhythmias and Treatments
- Congenital Heart Disease Studies
- Intensive Care Unit Cognitive Disorders
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Cardiovascular and Diving-Related Complications
- Infectious Aortic and Vascular Conditions
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiovascular Function and Risk Factors
- Blood transfusion and management
- Anesthesia and Sedative Agents
Woodlands Hospital
2019-2025
University of Insubria
2025
Magna Graecia University
2021-2024
University of Bari Aldo Moro
2021-2024
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2021
Cornell University
2021
ASL Roma
2021
Clinica Mediterranea
2021
Klinik für Schlafmedizin
2021
University Hospital Münster
2021
Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise post-MI VSD, likely driven by delays seeking treatment. This study retrospectively analyzed 10 cases VSD treated at our hospitals from March 2018 August 2023, comparing rates across pre-pandemic, and post-pandemic periods. The...
Gaseous micro-emboli (GME) represent a persistent risk in extracorporeal circulation systems, such as membrane oxygenation (ECMO) and cardiopulmonary bypass (CPB). These emboli can lead to severe complications, including neurological damage organ dysfunction, underscoring the urgent need for innovative solutions mitigate this risk. This study introduces evaluates novel device: polyvinyl chloride (PVC) arterial line equipped with gas extraction hypobaric oxygen flow system. The features an...
Background : In the conflict-affected setting of Kyiv, Ukraine, managing complex medical interventions presents significant challenges, especially for critically ill pediatric patients. This case report describes prolonged use extracorporeal membrane oxygenation (ECMO) in a 12-year-old girl with severe congenital heart disease, including critical aortic stenosis and myocarditis. absence transplant system limited resources, alternative solutions were explored to balance high risk...
Background and Objective: Effective cerebral perfusion monitoring is essential in aortic arch surgery, particularly when employing the Kazui technique under moderate hypothermia. Near-infrared spectroscopy (NIRS) provides real-time regional oxygen saturation (rSO2) measurements, while continuous of venous drainage flow extraction ratio (ERiO2) delivers additional insights into oxygenation metabolic balance. This study investigates correlation between NIRS-derived rSO2, flow, ERiO2 during...
Background and Objectives: Pediatric ECMO is a valid support mechanism for refractory cardiac and/or respiratory failure. Magnetic levitation technology applied to the centrifugal pump has reduced hemolysis caused by this procedure, which can be particularly dangerous, especially in neonates small children. ECMOLife, new magnetic pump, been introduced these patients. Materials Methods: Four patients were supported with ECMOLife System newborn setting, veno-venous application two cases...
This article presents an innovative surgical technique for the early detection, management, and quantification of paravalvular leaks (PVLs) during aortic valve replacement. The method utilizes endo-cavitary vent in right superior pulmonary vein to monitor blood flow oxygen saturation, which is crucial identification PVLs. Complementing this, transesophageal echocardiography (TEE) used real-time imaging detailed assessment regurgitant volume, providing a comprehensive evaluation leak...
Precise temperature management during cardiopulmonary bypass (CPB) is crucial for optimizing patient outcomes, influencing metabolic rate, organ protection, and neurological integrity. Traditionally, control CPB has relied on manual adjustments by perfusionists, a practice fraught with potential human error variability in outcomes. Such can lead to severe complications, including cerebral hyperthermia inflammatory responses, which significantly impact recovery morbidity. This paper...
ObjectiveMetabolism management plays an essential role during cardiopulmonary bypass (CPB). There are different metabolic devices integrated to heart–lung machines; the most commonly used and accepted target is indexed oxygen delivery (DO2i) (280 mL/min/m2) cardiac index (CI) (2.4 L/min/m2), which can be managed independently or according other parameters. Our objective was compare lactate production CPB procedures using management: DO2i in relation extraction ratio (O2ERi) CI mixed venous...
Introduction: Despite low mortality, cardiac surgery patients may experience serious life-threatening post-operative complications, often due to extracorporeal circulation and reperfusion. Miniaturised cardiopulmonary bypass (minimally invasive circulation) has been developed aiming reduce the risk of complications arising with conventional circulation. Methods: The COMICS trial is a multi-centre, international, two-group parallel randomised controlled testing whether type II, III or IV...
Introduction The ultimate answer to the question whether minimal invasive extracorporeal circulation (MiECC) represents optimal perfusion technique in contemporary clinical practice remains elusive. present study is a real-world that focuses on specific perfusion-related outcomes after cardiac surgery could potentially be favourably affected by MiECC and thereby influence future practice. Methods MiECS an international, multi-centre, two-arm randomized controlled trial. Patients undergoing...
The inflammatory response in cardiac surgery using extracorporeal circulation (ECC) has been widely discussed the literature with analysis on cytokines released humans; demonstrating manifold trigger causes. To mitigate this response—mainly linked to contact and recognition by blood of a “non-self” surface—many efforts have made make circuits extra-corporeal “biomimetics”; trying emulate cardio-vascular system. In other words, biomedical companies developed many biocompatible products order...
Insufflation of carbon dioxide (CO2) into the operative field to prevent cerebral or myocardial damage by air embolism is a well known strategy in open-heart surgery. However, here no general consensus on best delivery approach.From January 2018 November 2021, we retrospectively collected data one hundred consecutive patients undergoing minimally invasive mitral valve repair (MIMVR). Of these, fifty were insufflated with continuous CO2 1 min before opening left atrium and ended after its...
Creation of water condensation in blood oxygenators is a phenomenon that constantly present during cardiopulmonary bypass and medium- to long-term extracorporeal life support. Clinical observation at the oxygenator exit still common event normally associated with sudden cooling gas flow proximal outlet cover (after exiting fiber bundle), where warming effect no longer present. Condensation could progressively obstruct certain number fibers, reducing efficiency gaseous exchange membrane...
Abstract Infective endocarditis represents a surgical challenge associated with perioperative mortality. The aim of this study is to evaluate the predictors operative mortality and long-term outcomes in high-risk patients. We retrospectively analyzed 123 patients operated on for infective from January 2011 December 2020. Logistic regression model was used identify prognostic factors in-hospital Long term follow-up made asses late prognosis. Preoperative renal failure, an elevation EuroSCORE...
Abstract The role of inlet and outlet oxygenator pressure know as drop (Δ P ) in the elimination gaseous micro-emboli activity (GMEA) remains obscured during Extracorporeal Membrane Oxygenation (ECMO) Minimally Invasive Circulation (MiECC). There is conflicting literature on oxygenators well oxygenating performance, fluid dynamics micro-embolic elimination. We analyzed 14 procedures, 10 MiECC with polypropylene fibers ALONE AF 4 ECMO polymethylpentene Alone Oxygenator (Eurosets, SRL,...
Prevention of acute kidney injury during cardiopulmonary bypass (CPB) is still a challenge and has been the object numerous studies. The incidence in context CPB related to multifactorial etiology. role hemadsorption relation cell-free hemoglobin haptoglobin preservation not well defined literature on cardiac surgery procedures.
Background: Phosphorylcholine has emerged as a potential adjunctive agent in cardiopulmonary bypass (CPB) circuits. serves coating for the CPB circuit, potentially enhancing biocompatibility and reducing thrombotic events. However, its impact on specific patient populations procedural outcomes remains underexplored. Materials Methods: In this retrospective study, we analyzed data from 60 patients who underwent cardiac surgery with CPB, comprising 20 cases each of coronary artery grafting...