- Bacillus and Francisella bacterial research
- Genetically Modified Organisms Research
- Transgenic Plants and Applications
- Pneumocystis jirovecii pneumonia detection and treatment
- Viral gastroenteritis research and epidemiology
- Flavonoids in Medical Research
- Pneumonia and Respiratory Infections
- Colorectal Cancer Treatments and Studies
- Pharmacological Effects of Natural Compounds
- Bacteriophages and microbial interactions
- Medicinal Plants and Bioactive Compounds
- PI3K/AKT/mTOR signaling in cancer
- Antifungal resistance and susceptibility
- Cancer Mechanisms and Therapy
Department of Biotechnology
2020
Government of India
2020
MRC Laboratory of Molecular Biology
2011-2014
Jawaharlal Nehru University
2007-2009
Using genetically matched azole-susceptible (AS) and azole-resistant (AR) clinical isolates of Candida albicans , we recently demonstrated that CDR1 overexpression in AR is due to its enhanced transcriptional activation mRNA stability. This study examines the molecular mechanisms underlying stability isolates. Mapping 3′ untranslated region (3′ UTR) revealed it was rich adenylate/uridylate (AU) elements, possessed heterogeneous polyadenylation sites, had putative consensus sequences for...