A5022265396- Process Optimization and Integration
- Integrated Energy Systems Optimization
- Reservoir Engineering and Simulation Methods
- Oil and Gas Production Techniques
- Advanced Control Systems Optimization
- Energy Load and Power Forecasting
- Electric Power System Optimization
- Carbon Dioxide Capture Technologies
- Structural Integrity and Reliability Analysis
- Water Systems and Optimization
- Smart Grid Energy Management
- Hybrid Renewable Energy Systems
- Global Energy and Sustainability Research
- Spacecraft and Cryogenic Technologies
- Sustainable Supply Chain Management
- Heat Transfer and Optimization
- Heat Transfer and Boiling Studies
- Environmental Impact and Sustainability
- Atmospheric and Environmental Gas Dynamics
- Advanced Photocatalysis Techniques
- Non-Destructive Testing Techniques
- Risk and Safety Analysis
- Ga2O3 and related materials
- Drilling and Well Engineering
- Metabolomics and Mass Spectrometry Studies
Zhejiang Ocean University
2022-2025
Beijing University of Chinese Medicine
2024-2025
Wenzhou Medical University
2024-2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024-2025
Shanxi Medical University
2025
Shanghai University of International Business and Economics
2024
Tsinghua University
2019-2024
Center for Life Sciences
2021-2024
Hainan University
2023
Brno University of Technology
2019-2022
Abstract Cytokine release syndrome (CRS) is a major cause of the multi-organ injury and fatal outcome induced by SARS-CoV-2 infection in severe COVID-19 patients. Metabolism can modulate immune responses against infectious diseases, yet our understanding remains limited on how host metabolism correlates with inflammatory affects cytokine Here we perform both metabolomics cytokine/chemokine profiling serum samples from healthy controls, mild patients, delineate their global metabolic response...
Gastric cancer (GC) represents a significant burden of cancer-related mortality worldwide, underscoring an urgent need for the development early detection strategies and precise postoperative interventions. However, identification non-invasive biomarkers diagnosis patient risk stratification remains underexplored. Here, we conduct targeted metabolomics analysis 702 plasma samples from multi-center participants to elucidate GC metabolic reprogramming. Our machine learning reveals...
Although cancer cells are frequently faced with a nutrient- and oxygen-poor microenvironment, elevated hexosamine-biosynthesis pathway (HBP) activity protein O-GlcNAcylation (a nutrient sensor) contribute to rapid growth of tumor emerging hallmarks cancer. Inhibiting could be promising anticancer strategy. The gluconeogenic enzyme phosphoenolpyruvate carboxykinase 1 (PCK1) is downregulated in hepatocellular carcinoma (HCC). However, little known about the potential role PCK1 enhanced HBP HCC...
Metabolomics is a powerful and essential technology for profiling metabolic phenotypes exploring reprogramming, which enables the identification of biomarkers provides mechanistic insights into physiology disease. However, its applications are still limited by technical challenges particularly in detection sensitivity analysis biological samples with amount, necessitating development highly sensitive approaches. Here, we developed liquid chromatography tandem mass spectrometry method based...
The oil & gas transport and storage (OGTS) engineering, from the upstream of gathering processing in fields, to midstream long-distance pipelines, downstream tanks LNG terminals, while using supply chains connect each part, is exploring its way reduce energy consumption carbon footprints. This work provides an overview current methods technological improvements latest trends OGTS show how this industry strives achieve sustainable development goals. critical analyses are increasing...
Gas reservoir-type underground gas storage (UGS) plays a critical role in China’s natural reserves and peak shaving, serving as an essential component of the energy security system. Its unique cyclic injection production operations not only stabilize supply but also impose stringent requirements on safety integrity geological structures, wellbores, surface facilities. Weaknesses current practices can cause accidents, directly threatening security. Therefore, continuously improving management...