Using a bidirectional freezing technique, combined with uniaxial pressing and in situ polymerization, “nacre-mimetic” hydroxyapatite/poly(methyl methacrylate) (PMMA) composites are developed by processing large-scale aligned lamellar ceramic scaffolds. Structural mechanical characterization shows “brick-and-mortar” structures, akin to nacre, interesting combinations of strength, stiffness, work fracture, which provide pathway making strong tough lightweight materials.

Abstract Ordered mesoporous carbons (OMCs) have demonstrated great potential in catalysis, and as supercapacitors adsorbents. Since the introduction of organic–organic self-assembly approach 2004/2005 until now, direct synthesis OMCs is still limited to wet processing phenol-formaldehyde polycondensation, which involves soluble toxic precursors, acid or alkali catalysts, requires multiple steps, thus restricting widespread application OMCs. Herein, we report a simple, general, scalable...

Conventional superhydrophobic materials for oil/water separation were usually prepared from nondegradable and nonrenewable resources, which would not only increase resource crisis but also cause environmental pollution after discarding. In this study, we report a renewable biodegradable material, was fabricated via two-step curing dip-coating method composed of cellulosic filter paper or fabric, cured epoxidized soybean oil (CESO), ZnO, stearic acid (STA) as the substrate, adhesive, rough...

Based on Diels–Alder reaction, linear bisfuranic terminated poly(tetramethylene oxide) and poly(p-dioxanone) were crosslinked by tris(2-maleimide ethyl)amine; this process was fully reversible under moderate conditions. All of the results indicate that co-network possesses typical advantages chemical physical crosslinking, peculiar thermal invertibility, shape memory effect self-healability.

Background Given the important role of default mode network (DMN) in cognitive function and well-known neurocognitive deficit schizophrenia, it is intriguing to examine systematically relationship between dysfunction aberrant intrinsic activities, also functional connectivity, DMN patients with schizophrenia. Method First-episode, treatment-naive schizophrenia (FES) ( n = 115) healthy controls 113) underwent resting-state magnetic resonance imaging (fMRI) scans tests. Intrinsic neural...

Through pH-tuning of electrostatic interactions between polymer ligands and nanoparticles at structured-liquid interfaces, liquid droplets can be directed a jammed nonequilibrium state dynamic reconfigurable state. The nanoparticle-surfactant dynamics highly depend on the pH, so that liquids structured using an external field under variation or alternatively being realized by remote photo-triggering. As service to our authors readers, this journal provides supporting information supplied...

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe autoimmune disorder with mortality of 5%-7%, but few studies have focused on the predictors death in this disease. In study, we aim to investigate and causes patients anti-NMDAR encephalitis.In cohort were enrolled at West China Hospital Sichuan University between June 2011 October 2015. The outcomes evaluated by long-term follow-up. Cox regression analysis was used assess association potential death.Altogether 96 included...

The substitution of petroleum-based self-healing elastomers with biobased counterparts is crucial to the global sustainable development rubber industry, which highly depends on ease synthesis procedure. Herein, we show that stretchable, recyclable, and self-healable were synthesized via condensation polymerization succinic acid, adipic sebacic 1,4-butanediol in presence a small amount glycerol as curing agent 3,3′-dithiodipropionic acid dynamic covalent monomer. macroscopic properties our...

Background It is not clear whether the progressive changes in brain microstructural deficits documented previous longitudinal magnetic resonance imaging (MRI) studies might be due to disease process or other factors such as medication. important explore alterations white-matter (WM) microstructure antipsychotic-naive patients with first-episode schizophrenia during very early phase of treatment when relatively ‘free’ from chronicity. Method Thirty-five and 22 healthy volunteers were...

Metal oxides with high porosity usually exhibit better performance in many applications, as compared the corresponding bulk materials. Template-assisted method is generally employed to prepare porous metal oxides. However, template-assisted commonly operated wet conditions, which requires solvents, soluble oxide precursors, and a long time for drying. To overwhelm those drawbacks of procedure, mechanochemical nanocasting developed current work. Inspired by solid-state synthesis, this...

Insolubility and toxicity of TP restrict clinical applications in renal diseases. Here, TP-encapsulated mesoscale nanoparticles offer a new therapeutic strategy for diseases due to good biocompability, kidney targeting slow release.

Reversible Pickering emulsions, achieved by switchable, interfacially active colloidal particles, that enable on-demand emulsification/demulsification or phase inversion, hold substantial promise for biphasic catalysis, emulsion polymerization, cutting fluids, and crude oil pipeline transportation. However, particles with such a responsive behavior usually require complex chemical syntheses surface modifications, limiting their extensive use. Herein, we report simple route to generate...

Thermally-induced shape memory multiblock poly(ether-ester)s (PBSEGs) comprising crystallisable poly(butylene succinate) (PBS) hard segments and poly(ethylene glycol) (PEG) soft segments, were synthesized by polycondensation from succinic acid, 1,4-butanediol PEG diol. The copolymers characterized 1H-NMR, GPC, DSC DMA. analysis revealed that all PBSEGs prepared in this work are double-crystalline which ensure it to form separated crystalline domain determined the permanent temporary...

Diethylene glycol was incorporated into poly(butylene succinate) (PBS) to form biodegradable succinate-co-diethylene (P(BS-co-DEGS)) copolymer through a two-step procedure of esterification and polycondensation from succinic acid with 1,4-butanediol diethylene glycol. The chemical structure P(BS-co-DEGS) confirmed by proton nuclear magnetic resonance spectroscopy (1H NMR). effect DEGS content on the molecular weight, thermal properties, crystallization behaviors, hydrophilicity copolymers...

The self-assembly and interfacial jamming of spherical Janus nanoparticles (JNPs) at the water/oil interface were investigated. Polymeric JNPs, made by cross-linking polystyrene-block-polybutadiene-block-poly(methyl methacrylate) (PS-PB-PMMA), with a high activity assemble interface. During interface, energy was reduced dynamic interlayer observed that is responsive to pH aqueous phase. Unlike hard particles, JNPs are composed polymer chains can spread liquid-liquid maximize coverage...

Low molecular weight P2VP-b-PS-b-P2VP triblock copolymer (poly(2-vinlypyridine)-block-polystyrene-block-poly(2-vinylpyridine)] is doped with copper chloride and microphase separated into lamellar line patterns ultrahigh area density. Salt-doped self-assembled on the top of nanoimprinted photoresist template, metallic nanowires long-range ordering are prepared platinum-salt infiltration plasma etching.

The controlled structuring of liquids into arbitrary shapes can be achieved in biphasic liquid media using the interfacial assemblies nanoparticle surfactants (NP-surfactants), that consist a polar "head group" bound to one or more hydrophobic polymer "tails". nonequilibrium suspended phase rendered permanent by jamming NP-surfactants formed and assembled at interface between as system attempts minimize area liquids. While critical process, little is known dynamic mechanical properties...

Abstract Granular materials, composed of densely packed particles, are known to possess unique mechanical properties that highly dependent on the surface structure particles. A microscopic understanding structure‐property relationship in these systems remains unclear. Here, supra‐nanoparticle clusters (SNPCs) with precise structures developed as model elucidate unexpected elastic behaviors. SNPCs prepared by coordination‐driven assembly polyhedral oligomeric silsesquioxane (POSS)...

Polyoxometalates (POMs) using {Mo72V30} as an example, dissolved in water, can interact with amine-terminated polydimethylsiloxane (PDMS-NH2) toluene at the water/toluene interface to form POM-surfactants that significantly lower interfacial tension and be used stabilize liquids via elasticity. The jamming of water/oil consequent wrinkling occurs a decrease area. packing density tuned by varying strength screening addition cations differing hydrated radii.

Triptolide (TP) has been widely used in clinical medicine; however, it created a dilemma due to its toxicity and nonspecificity. Here, we reported biocompatible high-efficiency renal-targeting nanoplatform for renal ischemia/reperfusion injury (IRI) therapy, which the toxic drug of TP was encapsulated into folate (FA)-modified Pluronic F127/P123 nanoparticles (FPNPs). The TP-loaded FPNPs (TP-FPNPs) had good stability could effectively reduce cytotoxicity TP. Compared with (PNPs) group,...