Zildene de Sousa Silveira

ORCID: 0000-0003-1209-2814
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Insect and Pesticide Research
  • Insect Pest Control Strategies
  • Bee Products Chemical Analysis
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Antibiotics Pharmacokinetics and Efficacy
  • Phytochemistry Medicinal Plant Applications
  • Antimicrobial Resistance in Staphylococcus
  • Insect Utilization and Effects
  • Psidium guajava Extracts and Applications
  • Synthesis and biological activity
  • Antibiotic Resistance in Bacteria
  • Pharmacological Effects of Natural Compounds
  • Phytochemicals and Antioxidant Activities
  • Plant and animal studies
  • Science and Education Research
  • Phytochemistry and Biological Activities
  • Plant-Derived Bioactive Compounds
  • Microbial Metabolism and Applications
  • Botanical Research and Applications
  • Bioactive Compounds and Antitumor Agents
  • Biological Stains and Phytochemicals
  • Food Quality and Safety Studies
  • Computational Drug Discovery Methods
  • Ethnobotanical and Medicinal Plants Studies

Universidade Federal de Pernambuco
2020-2025

Universidade Regional do Cariri
2017-2023

Stingless bees belong to the Meliponini tribe and are widely distributed in tropics subtropics, where they perform important ecological services. Among best groups of stingless is genus Scaptotrigona, which includes 22 species throughout neotropical region, including area from Mexico Argentina. Bees this responsible for production products such as honey, propolis, geopropolis fermented pollen ("saburá"). This review aimed provide an overview chemical composition biological activities...

10.1002/cbdv.202301962 article EN Chemistry & Biodiversity 2024-02-28

The antibacterial activity and efflux pump reversal of thymol carvacrol were investigated against the Staphylococcus aureus IS-58 strain in this study, as well their toxicity Drosophila melanogaster. minimum inhibitory concentration (MIC) was determined using broth microdilution method, while inhibition assessed by reduction antibiotic ethidium bromide (EtBr) MICs. D. melanogaster tested fumigation method. Both presented activities with MICs 72 256 µg/mL, respectively. association between...

10.3390/molecules25092103 article EN cc-by Molecules 2020-04-30

The minimum inhibitory concentration (MIC) is used to define the lowest at which a substance can inhibit bacterial growth. This study aimed evaluate MIC of pyrogallol against Staphylococcus aureus and propose method for building growth inhibition curves strains from assays. S. 1199B (NorA) 1199 (wild type) were Pyrogallol tests performed by broth microdilution method. proposed uses RGB images plate using R (Red), G (Green), B (Blue) channels extract information construction curve (GIC)....

10.3390/biologics2020011 article EN cc-by Biologics 2022-05-20

The Gram-positive bacterium Staphylococcus aureus is responsible for a number of infections and has been described to exhibit resistance antibacterial drugs through different mechanisms. Among these, active efflux shown be one the main mechanisms bacterial associated with S. aureus. In this sense, aim present study was evaluate ability ellagic acid gallic reverse by inhibiting pumps in strains IS-58 K2068, which express TetK MepA flux pumps, respectively. addition, toxicity both compounds...

10.1242/bio.059434 article EN cc-by Biology Open 2022-09-05

Efflux pumps are transmembrane proteins that expel drugs out of a bacterial cell contributing to microorganism drug resistance. Several studies addressing the use natural products with medicinal properties have intensified given above. Thus, aim present study was investigate antibacterial activity and O-eugenol potential in Staphylococcus aureus resistance reversal by efflux pump inhibition, as well evaluate its toxicity Drosophila melanogaster arthropod model. The broth microdilution method...

10.1155/2022/1440996 article EN cc-by BioMed Research International 2022-07-19

This study aimed to evaluate the antibacterial activity against multi-drug-resistant strains carrying efflux pumps and assess their toxicity on Drosophila melanogaster Aedes aegypti models. Microdilution tests in broth were performed determine Minimum Inhibitory Concentration (MIC). The pump inhibition was evaluated by analyzing reduction antibiotic MIC Ethidium Bromide (EtBr) when combined with products. Mortality assay negative geotaxis conducted D. specimens, insecticidal assays A....

10.1016/j.toxrep.2025.101917 article EN cc-by-nc-nd Toxicology Reports 2025-01-19

To identify the main chemical classes of compounds from aqueous extract Enterolobium contortisiliquum (E. contortisiliquum) seed bark and to evaluate its antibacterial activity, as well potential increase activity antibiotics against strains Staphylococcus aureus, Pseudomonas aeruginosa Escherichia coli. Different in E. were evaluated based on visual changes coloration formation precipitate after addition specific reagents. The antibiotic drugs, gentamicin norfloxacin was determined by using...

10.1016/j.apjtb.2017.09.006 article EN Asian Pacific Journal of Tropical Biomedicine 2017-09-11

Bacterial resistance is interfering with the action of antibiotics for clinical use in treating pathologies. The search new substances capable combating this necessary. An alternative to these extract medicinal plants. Plathymenia reticulata, plant Fabaceae family, a common tree species from Brazilian cerrado, and commonly used areas environmental degradation. This rich phenolic compounds, such as flavonoids tannins, compounds that are associated various biological effects. A hydroethanolic...

10.1016/j.toxrep.2021.03.020 article EN cc-by-nc-nd Toxicology Reports 2021-01-01

Bacteria are associated with many infections that affect humans and present antibiotic resistance mechanisms, causing problems in health organisations increased mortality rates. Therefore, it is necessary to find new antibacterial agents can be used the treatment of these microorganisms. Geopropolis a natural product from stingless bees, formed by mixture plant resins, salivary secretions, wax soil particles, chemical composition this diverse. Thus, study aimed evaluate activity, modulation...

10.1002/cbdv.202300931 article EN Chemistry & Biodiversity 2023-09-30

Azadirachta indica A. Juss, is a large tree, native to India and Meliaceae family, has in its phytochemical constitution many phenolic compounds, several of parts have been used for medicinal purposes as antifungal, antibacterial antidiabetic. The objective was define the profile ethanolic extract leaves (EEAi) determine toxicity Drosophila melanogaster model. quantification chemical constituents done by High Performance Liquid Chromatography (HPLC) evaluate model D. melanogaster, where it...

10.3390/mol2net-04-05557 article EN cc-by Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition 2018-10-25
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