A5014142094- Plant Stress Responses and Tolerance
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Selenium in Biological Systems
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Plant nutrient uptake and metabolism
- Renal cell carcinoma treatment
- Ferroptosis and cancer prognosis
- Epigenetics and DNA Methylation
- GABA and Rice Research
- Plant responses to water stress
- Renal and related cancers
- Plant Gene Expression Analysis
- Magnetic and Electromagnetic Effects
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Light effects on plants
- PARP inhibition in cancer therapy
- BRCA gene mutations in cancer
- Trace Elements in Health
- Polysaccharides and Plant Cell Walls
- Multiple and Secondary Primary Cancers
- Aluminum toxicity and tolerance in plants and animals
Henan Agricultural University
2019-2025
Nanjing Medical University
2016-2025
Rice University
2024-2025
Jiangsu Cancer Hospital
2014-2025
Changchun University of Science and Technology
2024
Tongji University
2023
Shanghai Tenth People's Hospital
2023
Tobacco Research Institute
2023
Lanzhou University
2021-2022
Jiangxi Agricultural University
2020
Exosomes, carriers to transfer endogenous molecules, derived from bone marrow-derived mesenchymal stem cells (BMSCs) have been reported play a role in the progression of bladder cancer. Here we aimed test functional mechanism microRNA-9-3p (miR-9-3p)-containing exosomes BMSCs were cocultured with cancer cells, and secreted identified. Next, expression miR-9-3p endothelial cell-specific molecule 1 (ESM1) tissues was determined. Then effects ESM1 via BMSC-derived on cell viability, migration,...
Molybdenum (Mo) is widely used as a micronutrient fertilizer to improve plant growth and soil quality. However, the interactions between cell wall biosynthesis molybdenum have not been explored sufficiently. This study thoroughly investigated regulatory effects of different concentrations Mo on tobacco from physiological metabolomic aspects. The results indicate that treatment increased content variety K326. Moreover, it significantly up-regulated gene expression levels molybdases (NR, AO,...
In this study, we treated tobacco seedlings with 0, 200, 400, and 800 mg/kg Pb2 +, explored the response mechanism of under Pb stress through a combination growth physiology metabolomics analysis. The physiological results showed that compared CK, increase concentration, treatment inhibited growth, reduced biomass photosynthetic pigment content seedlings, severely damaged chloroplast structure. addition, pore conductivity density Pb800 decreased by 45.77 % 93.55 %, respectively. disrupted...
Abstract Cold temperatures often severely restrict the growth, distribution and productivity of plants. The freezing tolerance plants from temperate climates can be improved by undergoing periods cold acclimation (CA). Tobacco is an important economic plant sensitive to stress. However, dynamic changes regulatory mechanisms gene expression metabolic processes during CA remain largely unknown. In this study, we performed RNA sequencing metabolomic profiling analyses identify genes metabolites...
Tobacco black shank (TBS), caused by Phytophthora nicotianae, poses a significant threat to tobacco plants. Selenium (Se), recognized as beneficial trace element for plant growth, exhibited inhibitory effects on P. nicotianae proliferation, disrupting the cell membrane integrity. This action reduced energy supply and hindered hyphal transport through proteins, ultimately inducing apoptosis. Application of 8 mg/L Se leaf spraying resulted in notable decrease TBS incidence. Moreover, treatment...
To identify prognostic genes which were associated with adrenocortical carcinoma (ACC) tumor microenvironment (TME).Transcriptome profiles and clinical data of ACC samples collected from The Cancer Genome Atlas (TCGA) database. We use ESTIMATE (estimation stromal Immune cells in malignant tissues using expression data) algorithm to calculate immune scores, scores estimate scores. Heatmap volcano plots applied for differential analysis. Venn used intersect selection. protein-protein...
Salinity is one of the most severe forms abiotic stress and affects crop yields worldwide. Plants respond to salinity via a sophisticated mechanism at physiological, transcriptional metabolic levels. However, molecular regulatory networks involved in salt alkali tolerance have not yet been elucidated. We developed an RNA-seq technique perform mRNA small RNA (sRNA) sequencing plants under (NaCl) (NaHCO
Abstract To gain insight into the molecular mechanisms underpinning tobacco ( Nicotiana tabacum ) tolerance to drought stress, we integrated anatomical, physiological, and proteomic analyses of drought-tolerant (Yuyan6, [Y6]) -sensitive (Yunyan87 [Y87]) varieties. In comparison Y87, Y6 exhibited higher water retention capability, improved photosynthetic performance, delayed leaf-senescence, stable leaf ultrastructure, a stronger antioxidant defense, lesser ROS accumulation when subjected...
Drought is a major abiotic stress that restricts plants growth, development, and yield. Coronatine (COR), mimic of JA-Ile, functions in plant tolerance to multiple stresses. In our study, we examined the effects COR tobacco under polyethylene glycol (PEG) stress. treatment improved growth as measured by fresh weight (FW) dry (DW). The enzyme activity assay indicated that, osmotic conditions, activities superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX), glutathione...
The maturity of tobacco leaves directly affects their curing quality. However, no effective method has been developed for determining during production. Assessment flue long depended on production experience, leading to considerable variation. In this study, hyperspectral imaging combined with a novel algorithm was used develop classification model that could accurately determine the leaves. First, different levels (unripe, under-ripe, ripe, and over-ripe) were collected. ENVI software...
Abstract We developed this study to describe the patterns of distant metastasis (DM) and explore predictive prognostic factors DM in clear cell renal carcinoma (ccRCC) patients. collected eligible patients from Surveillance, Epidemiology, End Result (SEER) database 2010 2015. Then, comparisons baseline characteristics between different metastatic were made. In addition, proportional mortality ratios (PMRs) proportion trends calculated. Afterward, survival outcomes explored by Kaplan–Meier...