A5010431622- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- Effects of Radiation Exposure
- Advanced Radiotherapy Techniques
- Cancer, Hypoxia, and Metabolism
- CAR-T cell therapy research
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Virus-based gene therapy research
- Immunotherapy and Immune Responses
- Hepatocellular Carcinoma Treatment and Prognosis
- RNA modifications and cancer
- MicroRNA in disease regulation
- Esophageal Cancer Research and Treatment
- Immune cells in cancer
- Renal and related cancers
- Glioma Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
- Circular RNAs in diseases
- CRISPR and Genetic Engineering
West China Hospital of Sichuan University
2016-2025
Sichuan University
2016-2025
Harbin Medical University
2025
Third Affiliated Hospital of Harbin Medical University
2025
Agriculture and Agri-Food Canada
2025
State Key Laboratory of Biotherapy
2014-2024
Affiliated Hospital of Youjiang Medical University for Nationalities
2024
Ningxia Medical University
2024
Capital Medical University
2024
Shanxi University
2022-2024
Abstract Immunotherapy represented by anti-PD-(L)1 and anti-CTLA-4 inhibitors has revolutionized cancer treatment, but challenges related to resistance toxicity still remain. Due the advancement of immuno-oncology, an increasing number novel immunoregulatory targets mechanisms are being revealed, with relevant therapies promising improve clinical immunotherapy in foreseeable future. Therefore, comprehending larger picture is important. In this review, we analyze summarize current landscape...
Allosteric transitions can modulate the self-assembly and biological function of proteins. It remains, however, tremendously challenging to design synthetic allosteric polymeric assemblies with spatiotemporally switchable hierarchical structures functionalities. Here, a photoallosteric polymersome is constructed that undergoes rapid conformational transition from β-sheet α-helix upon exposure near-infrared light irradiation. In addition improving nanoparticle cell penetration lysosome...
Maple syrup is often adulterated by dilution or substitution with other syrups due to its high demand and price. Fingerprinting techniques, e.g., DNA barcoding, detect adulteration in foods. However, extensive processing during the transformation of sap into degrades genetic material, lowering efficacy this approach. In contrast, fluorescence fingerprints (EEMs) rely on a sample's intrinsic fluorophores provide valuable information for detecting adulteration. This study evaluates...
Abstract CD38 is the main enzyme for nicotinamide adenine dinucleotide (NAD) degradation in mammalian cells. Decreased NAD levels are closely related to metabolic syndromes and aging-related diseases. Our study showed that deficiency significantly alleviated angiotensin II (Ang II)-induced vascular remodeling mice, as shown by decreased blood pressures; reduced media thickness, media-to-lumen ratio, collagen deposition; restored elastin expression. However, our bone marrow transplantation...
The smart farm is currently a hot topic in the agricultural industry. Due to complex field environment, intelligent monitoring model applicable this environment requires high hardware performance, and there are difficulties realizing real-time detection of ripe strawberries on small automatic picking robot, etc. This research proposes multistage strawberry algorithm YOLOv5-ASFF based improved YOLOv5. Through introduction ASFF (adaptive spatial feature fusion) module into YOLOv5, network can...
Radiation-induced lung injury (RILI) presents a common and major obstacle in the radiotherapy of thoracic cancers. The aim this study was to examine whether RILI could be alleviated by mesenchymal stem cells (MSCs) expressing soluble transforming growth factor-β (TGF-β) type II receptor via an adenovirus (Ad-sTβR). Here, we systemically administered male MSCs into female mice challenged with irradiation. data showed that either or Ad-sTβR transduced (Ad-sTβR-MSCs) specifically migrated...