A5064611474- Cardiovascular Disease and Adiposity
- Diabetes and associated disorders
- Lipoproteins and Cardiovascular Health
- Cardiac Imaging and Diagnostics
- Anesthesia and Neurotoxicity Research
- Hormonal and reproductive studies
- Blood Coagulation and Thrombosis Mechanisms
- Biomarkers in Disease Mechanisms
- Cardiac Ischemia and Reperfusion
- Pregnancy and preeclampsia studies
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Medical research and treatments
- Dementia and Cognitive Impairment Research
- Rheumatoid Arthritis Research and Therapies
- Estrogen and related hormone effects
- Venomous Animal Envenomation and Studies
- Cardiovascular Effects of Exercise
- Angiogenesis and VEGF in Cancer
- Healthcare Systems and Public Health
- Chronic Disease Management Strategies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bone Metabolism and Diseases
- Child and Adolescent Health
- Poisoning and overdose treatments
Universidad Autónoma de Bucaramanga
2023-2024
Introduction: MMP type 9 (MMP-9) plays an important role in the degradation of extracellular matrix, destabilizing atherosclerotic plaques. Materials and methods: A prospective open study was carried out a South American hospital. All patients gave their voluntary informed consent to participate process results survey. The scientific work approved by local ethics committee Educational Institution Higher Education. Results: During recruitment index group, we examined 297 people. Our included...
Introduction: The present study sought to thrombophilias associated with venous thromboembolism during pregnancy. Methods: is of a descriptive observational type in which the clinical and laboratory alterations were analyzed cohort Latin American pregnant women denominator thrombotic events Results: mean age was 24.5+7.6 years, 9 patients (10.3%) had history , 23 (26.4%) at least one fetal loss. Elevated Antiphosphatidylserine antibodies found (26.4%), elevated against Beta2-Glycoprotein 20...
Introduction: Among all cardiovascular complications in patients after cardiac surgery, new-onset postoperative atrial fibrillation is one of the most common and develops 30-50% cases. Methodology: Original cohort study that was carried out a South American level IV hospital from 2015-2018. Results: mean age main group 67.00 (61.00; 72.75) years, control group, 62.50 (57.25; 67.00) years (r =0.22; 95% CI: 0.02-0.43; p =0.04). In our study, risk according to EuroSCORE II scale 0.90 (0.72;...
Introduction : The study of the role genetic markers hemostasis disorders in CHF with both preserved (HFPEF) and reduced (HFREF) LVEF patients DM2 has not been adequately addressed . Methods We used “ Genetics Hemostasis ” kits from company DNA Technology (USA). Amplification was performed a DT-Prime 5 amplifier (DNA , USA) for prothrombin factor V gene polymorphisms. Results: F13 (rs5985) fibrinogen (rs1800790): they are more common HFPEF than control group HFREF ; ITGA2 (rs1126643): less...
Objective. The objective of the study was to relationship between AR gene polymorphism and parameters carbohydrate lipid metabolism, as well endothelial function in men with type 2 diabetes mellitus a South American cohort. Materials methods. All patients underwent vasomotor endothelium using ultrasound brachial artery biochemical markers dysfunction ICAM-1, VCAM-1, p-selectin, e- selectin. Results. number CAG repeats had significant positive regression level total testosterone, weak...
Objective. Evaluation of the pathogenic factor autoimmune hypogonadism in men with a positive MAR IgG test result and type 1 diabetes mellitus (DM1) South American cohort. Materials Methods. The retrospective study included 97 result: 30 patients T1DM 67 without diabetes. examination determination total testosterone titer antibodies against steroid-producing cells reproductive tissue. Differences were considered statistically significant when p<0.05. Results.The incidence high titers...
Objective. To evaluate the diagnostic accuracy of exercise stress echocardiography(EchoCG) on a horizontal bicycle ergometer for detection obstructive coronary heart disease(oCAD) in patients with low-risk non-ST-segment elevation acute syndrome(NSTEACS). Material and methods. The study included 95 patients, mean age 53 years, 58% men hospitalized department regional vascular center diagnosis NSTE-ACS were at low risk. Patients known disease impaired left ventricular contractility rest not...
<h3>Background:</h3> Cardiovascular disease is a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), psoriatic (PA). Women SLE are reported to have 5- 6-fold increased risk developing cardiovascular disorders (CVD), as well RA 2- 3-fold myocardial infarction and, up 50% CVD mortality. SLE, PA prevalent indicators rheumatology, so assessment comorbidities can play role the prioritization selection appropriate treatment...
Abstract Introduction T2DM is a chronic disease that affects millions of people worldwide. In older adults, may be associated with an increased risk two serious conditions: cognitive impairment and depression. Objective The aim this research was to assess the mental health adults type 2 diabetes mellitus (T2DM) in Mérida, Venezuela. Methodology A cross-sectional study conducted 100 without T2DM. Two assessment instruments were used: Mini Mental State Examination (MMSE) function Geriatric...
Del Nido cardioplegia (DNC) has been used in the paediatric population since early 1990s, achieving adequate myocardial protection. In addition, initial investigations adults have demonstrated reduced damage and improved functional recovery post-operatively. As utiilization of minimally invasive cardiac surgery is increasing as an alternative to traditional sternotomy, application a solution that could provide protection for long period time would be ideal given limited working space...
Results During 36 months, 721 patients underwent CABG. Only older that 70 years-old with an acute coronary syndrome were included. High risk was defined as Euroscore I greater than 7. Exclusion criterias Chronic Renal Failure, off-pump surgery and additional procedures. 85(12%) selected for analysis. Mean Age 75(70-87). 56(65.9%) male 29(34.1%) female. 10(8-20). EF 46%(+/-11). Left-main obstruction present in 13(15%). Cardioplegic solution administered randomly. HCS to 40(47%) HTK 45(53%)...
Abstract INTRODUCTION One of the pathogenic links between type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD) is low-intensity chronic inflammation, which limited by FoxP3+ regulatory T cells. MATERIALS AND METHODS A comparative, observational, single-center, single-stage study was carried out. The severity atherosclerosis assessed calculating Gensini score based on selective angiography. absolute relative content CD4+CD25 high low cells in blood evaluated flow cytometry....
Abstract INTRODUCTION In South America, heart failure poses a substantial concern due to its widespread occurrence and insufficient data accuracy. Metabolic syndrome, risk factor for disease diabetes, is the focal point of study, which seeks examine correlation with left ventricular diastolic function (LVDF) indications in adults within American hospital. MATERIALS AND METHODS A cross-sectional study 2380 aged 65-79 hospital reveals connections between metabolic syndrome (MetS) health. Using...
Objective. The aim of the study is carrying out a comparative analysis expression RFs and their receptors in non-healing chronic ulcer defects different duration diabetic foot syndrome South American cohort. Methods. Immunohistochemical biopsy samples was performed using antibodies against following risk factors receptors: vascular endothelial factor (VEGF), insulin-like (IGF), epidermal (EGF). Depending on wound, biopsies were divided into 3 groups. Results. In wound whose did not exceed 90...
Introduction to study the characteristics of anamnestic history, clinical course, as well nature medical care for elderly patients with acute myocardial infarction (MI) and evaluate their impact on prognosis disease. Material methods included aged 60 years or older, survivors registered in database Hospital Universitario de los Andes Merida, Venezuela (n=410). During 2013-2018 study, a five-year prospective observation an assessment vital status was conducted. For statistical processing data...
Introduction . It was previously believed that markers of the autoimmune process, specifically autoantibodies ( Abs ) against β cells in patients with type 1 diabetes mellitus (DM1), persist only during first 5 years disease. Contrary to established opinion, some long- term T1D showed elevated levels β-cell destruction as well residual insulin secretory function, determined by fasting C-peptide level. According various sources, prevalence this observations ranges between 12 and 48%.
ABSTRACT Introduction to assess the lipid-lowering effect, effect on endothelial function, oxidative stress of Rosuvastatin at a dose 40 mg in patients with dyslipidemia, arterial hypertension (AH) and chronic obstructive pulmonary disease (COPD) initially, over time after 4 weeks 12 months treatment. Material methods The prospective study included 33 (mean age 60 [54;61] years) hypertension, COPD dyslipidemia. laboratory examination consisted determining lipid spectrum level peroxidation...
Objective: To assess the cardiometabolic profile and cardiovascular risk factors in women with a history of arterial hypertension (HTN) during pregnancy. Materials methods: an observational case-control study based on prospective cohort included 66 divided into two groups: group I - pregnancy (n=33), II (control) normotensive pregnancies (n=33). We used propensity score matching method. Results: structure I, obesity more often prevailed comparison control group. When assessing profile,...
El término pediatría surge del griego paidos (niño) e iatrea (curación). Inicialmente, la fue descrita como una de las ramas independientes medicina en Europa Central durante segunda mitad siglo XIX; se independizó áreas obstetricia y interna forma progresiva. Fue por primera vez 1722 el tratado Paedojatreja práctica profesor anatomía teoría médica Theodor Zwinger Universidad Basileam. Los escritos más antiguos los que tiene conocimiento enfermedades población pediátrica datan 2100 a. C.,...