- Neurotransmitter Receptor Influence on Behavior
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Neuroendocrine regulation and behavior
- Receptor Mechanisms and Signaling
- Pediatric Pain Management Techniques
- Neuroscience of respiration and sleep
- Bone health and treatments
- Higher Education Practises and Engagement
- Anesthesia and Neurotoxicity Research
- Bone Metabolism and Diseases
- Birth, Development, and Health
- Higher Education and Employability
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Pain Mechanisms and Treatments
- Regulation of Appetite and Obesity
- Ion channel regulation and function
- Hearing, Cochlea, Tinnitus, Genetics
- Higher Education Research Studies
- MicroRNA in disease regulation
- Thyroid Disorders and Treatments
- Nerve injury and regeneration
Southern Cross University
2025
Hunter Medical Research Institute
2014-2023
University of Newcastle Australia
2015-2021
Abstract MicroRNAs (miRNAs) within the ventral and dorsal striatum have been shown to regulate addiction‐relevant behaviours. However, it is unclear how cocaine experience alone can alter expression of miRNAs striatal subregions. Further, not known whether differential in contributes individual differences addiction vulnerability. We first examined effect self‐administration on miR‐101b, miR‐137, miR‐212 miR‐132 nucleus accumbens core shell (NAcSh), as well dorsomedial dorsolateral (DLS)....
Recently, we published data using an animal model that allowed us to characterize animals into two groups, addiction vulnerable and resilient, where identified addiction/relapse vulnerability was associated with deficits in synaptic plasticity-associated gene expression the dorsal striatum (DS). Notable strong reduction for activity-regulated cytoskeleton-associated protein (Arc) considered a master regulator of plasticity. In present study, confirmed Arc messenger RNA significantly...
University diplomas in Australia provide pathways into higher education for a diverse cohort of students, including students who do not meet the academic requirements bachelor course. Despite role university widening participation and addressing inequities access to education, there is paucity research about diploma students. This mixed-method study investigated experiences outcomes entering through diplomas. Quantitative qualitative findings showed that found be beneficial beginning their...
Sodium channel expression in inner ear afferents is essential for the transmission of vestibular and auditory information to central nervous system. During development, however, there also a transient Na+ channels hair cells. Using qPCR analysis, we describe four genes, SCN5A (Nav1.5), SCN8A (Nav1.6), SCN9A (Nav1.7), SCN10A (Nav1.8) human fetal cristae ampullares, utricle, base, middle, apex cochlea. Our data show distinct patterns gene with age between these organs. In was general trend...
Abstract Early-life inflammation can have long lasting impact on pain processing and behaviours. For example, we shown neonatal result in changes within spinal neuronal networks altered flinching of the hind paw following formalin injection three weeks later. This suggests mechanisms for behaviours lie first second order neurons neuroaxis. Exactly how these progress during postnatal development is not known. Accordingly, investigated neuroinflammatory markers sensory (dorsal root ganglia;...