- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Family and Patient Care in Intensive Care Units
- Pediatric Pain Management Techniques
- Anesthesia and Neurotoxicity Research
- Infant Development and Preterm Care
- Respiratory Support and Mechanisms
- Geriatric Care and Nursing Homes
- Diabetes Management and Education
- Healthcare Decision-Making and Restraints
- Neonatal Respiratory Health Research
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Childhood Cancer Survivors' Quality of Life
- Long-Term Effects of COVID-19
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare cost, quality, practices
- Neonatal Health and Biochemistry
- Interprofessional Education and Collaboration
- Health Policy Implementation Science
- Palliative Care and End-of-Life Issues
- COVID-19 and Mental Health
- Heart Failure Treatment and Management
- Cerebral Palsy and Movement Disorders
- Cardiac Arrest and Resuscitation
Erasmus MC
2016-2025
Erasmus MC - Sophia Children’s Hospital
2016-2025
Erasmus University Rotterdam
2010-2025
Geneeskundige en Gezondheidsdienst
2023
University of Copenhagen
2022
Johns Hopkins Medicine
2021
Johns Hopkins University
2021
Intensive Care Society
2015
Boston Children's Hospital
2005-2014
Guy's and St Thomas' NHS Foundation Trust
2012
To determine prevalence of delirium in critically ill children and explore associated risk factors.
Objectives: The original COMFORT scale, including both observational and physiologic items, has been validated for measuring distress in children admitted to a pediatric intensive care unit. However, variables are influenced by drugs given the unit setting. objectives of this study were assess usefulness judgment sedation determine new cutoff points "behavioral" scale (COMFORT-B), using only items. Design: Prospective study. Setting: Pediatric university hospital Patients: Seventy-eight...
Objectives: To evaluate current international practice in PICUs regarding components of the “Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice Sedation, Delirium Monitoring/Management, Early Exercise/Mobility, Family Engagement/Empowerment” (ABCDEF) bundle. Design: Online surveys conducted between 2017 2019. Setting: One-hundred sixty-one across United States ( n = 82), Canada 14), Brazil 27), Europe 38) participating Prevalence Acute Rehabilitation for Kids PICU study....
To establish frequencies of benzodiazepine and opioid withdrawal symptoms, correlations with total doses duration administration.A prospective, repeated-measures design.Two pediatric intensive care units in a university children's hospital.Seventy-nine children, aged 0 days to 16 yrs, who received intravenous midazolam and/or opioids for >5 days.None.Pediatric unit nurses assessed symptoms using the Sophia Benzodiazepine Opioid Withdrawal Checklist, which includes all (n = 24) described...
To construct a reliable and clinically practical instrument for monitoring opioids benzodiazepine withdrawal symptoms in pediatric ICU patients.Instrument development.Intensive care unit an academic children's hospital.79 patients up to age 16 years on intravenous midazolam and/or > or =5 days. An expert panel of 85 physicians nurses rated clinical relevance symptoms.During drug weaning repeated observations were performed with checklist 24 described the literature.For 76 children, 932...
The Sophia Observation withdrawal Symptoms scale is an instrument for screening benzodiazepine and opioid syndrome in pediatric critical care patients. objectives of this study were to establish cutoff scores test sensitivity change. Second, risk factors explored.Prospective observational with repeated measures.Level IV ICU at a university children's hospital.A total 154 children median age 5 months (interquartile range, 0-42 mo) who received continuous infusion benzodiazepines and/or...
ABSTRACT Background Delirium is a common form of vital organ dysfunction in intensive care unit (ICU) patients and associated with poor outcomes. Adherence to guideline recommendations pertaining delirium still suboptimal. Aims We performed survey aimed at identifying barriers for implementation that should be addressed tailored intervention targeted improved ICU adherence. Design The was conducted among professionals. Methods An online 360 health professionals (nurses, physicians...
Abstract Background The COMFORT behaviour scale ( ‐ B scale) is widely used in paediatric intensive care units to assess young children's pain and distress. It also the impact of treatment interventions, but little known on scale's sensitivity detect changes between before after measurements following an intervention. This study explored change scale. Methods scores, originally prospectively collected as part standard care, were retrieved from digital patient data management system. We...
This study investigated self-management challenges and support needs experienced by kidney transplant recipients.After transplantation, recipients are expected to take an active role in self-management. However, evidence suggests that nurses experience difficulties operationalizing support. Greater insight into the recipients' perspective could help improve adequacy efficacy of nurse-led support.A cross-sectional qualitative study.Focus groups individual interviews were carried out with...
Management and monitoring of pain sedation to reduce discomfort as well side effects, such over- under-sedation, withdrawal syndrome delirium, is an integral part pediatric intensive care practice. However, the current state management analgosedation across European units (PICUs) remains unknown. The aim this survey was describe practices PICUs regarding sedation.
Many pediatric intensive care units use the COMFORT-Behavior scale (COMFORT-B) to assess pain in 0- 3-year-old children. The objective of this study was determine whether is also valid for assessment children with Down syndrome. These often undergo cardiac or intestinal surgery early life and therefore admission a unit. Seventy-six patients syndrome were included 466 without Pain regularly assessed COMFORT-B Numeric Rating Scale (NRS). For either group, confirmatory factor analyses revealed...
Abstract Aims To unravel outpatient nurses' views on the role of people with chronic conditions in self‐management, own support and to establish how these relate nurse‐led self‐management interventions. Background Providing is a core task nurses care. However, concept interpreted different ways little known about patients' role. Design Qualitative design. Methods Individual semi‐structured interviews were held 2012–2013 at university medical hospital Netherlands. After transcription,...
Reports of increasing incidence rates delirium in critically ill children are reason for concern. We evaluated the measurement properties pediatric component (PD-scale) Sophia Observation Withdrawal Symptoms scale Pediatric Delirium (SOS-PD scale). In a multicenter prospective observational study four Dutch ICUs (PICUs), patients aged ≥ 3 months and admitted 48 h were assessed with PD-scale thrice daily. Criterion validity was assessed: if score 4, child psychiatrist clinically presence or...