A5050843316- Temporomandibular Joint Disorders
- Orthodontics and Dentofacial Orthopedics
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal synovial abnormalities and treatments
- dental development and anomalies
- Medical and Biological Sciences
- Botulinum Toxin and Related Neurological Disorders
- Health Literacy and Information Accessibility
- Otitis Media and Relapsing Polychondritis
- Social Media in Health Education
- Cell Adhesion Molecules Research
- Dental Radiography and Imaging
- Osteomyelitis and Bone Disorders Research
- Systemic Lupus Erythematosus Research
- Myofascial pain diagnosis and treatment
- Craniofacial Disorders and Treatments
- Oral microbiology and periodontitis research
- Neurogenetic and Muscular Disorders Research
- Family and Disability Support Research
- Facial Nerve Paralysis Treatment and Research
- Artificial Intelligence in Healthcare and Education
- Autoimmune Neurological Disorders and Treatments
- Dental Health and Care Utilization
Aarhus University
2014-2024
University of Calgary
2017-2024
Emory University
2024
Malmö University
2022
Aarhus University Hospital
2012-2019
Massachusetts General Hospital
2019
Harvard University
2019
Boston Children's Hospital
2019
University of Bergen
2018
Hospital for Sick Children
2017
Unilateral temporomandibular joint (TMJ) arthritis in juvenile idiopathic (JIA) patients often induces asymmetric dentofacial growth. This study evaluates the effects of an orthopaedic functional appliance worn full time to reduce mandibular growth JIA patients. Twenty-two with unilateral TMJ involvement were included (mean age 7.5 years, range: 3.8-13.8 years). They all received treatment a appliance, so-called distraction splint 57 months). Panoramic tomograms or cone beam-computerized...
The intra-osseous pressure, PO2, and PCO2 were measured in 32 hips (21 patients) which painful but showed no severe degenerative changes. Pre-operative scintigraphy radiography was performed all patients. Thirteen early osteoarthritis, eight had osteonecrosis, 11 Core biopsies the bone examined histologically graded for necrosis. Histologically, necrosis present 27 specimens. Scintigraphic findings did not correlate with histological results more closely related to radiographic findings....
Patients with juvenile idiopathic arthritis (JIA) and involvement of the temporomandibular joint (TMJ) often experience abnormal facial growth. Three-dimensional (3D) assessment dentofacial growth deviation has become more common advancement commercialization imaging technologies. However, no standardized guidelines exist for interpretation 3D in patients JIA. The aim this study was to propose validate morphometric measures radiographic JIA enhance: 1) Description deviation; 2) Treatment...
Objective To estimate the cumulative incidence of arthritis‐induced orofacial symptoms, dysfunction, and dentofacial deformities in growing individuals with juvenile idiopathic arthritis ( JIA ) a 36‐month regional cohort study to identify predictors for development deformities. Methods Data were retrieved from Aarhus temporomandibular joint TMJ register, which contains standardized, longitudinal, observational data regarding conditions patients (n = 1,040). This represents majority all...
Patients seeking orthodontic treatment may use large language models (LLMs) such as Chat-GPT for self-education, thereby impacting their decision-making process. This study assesses the reliability and validity of prompts aimed at informing patients about side effects examines patients' perceptions this information.
Summary Analysis of temporomandibular joint ( TMJ ) synovial fluid may elucidate the aetiology disorders and arthritic conditions, as well inflammatory mechanisms involved. Knowledge about healthy is necessary to understand pathologies. We aimed quantify proinflammatory cytokines interleukin IL )‐1 β , ‐2, ‐6 tumour necrosis factor TNF ), anti‐inflammatory ‐10 interferon IFN )‐ γ in serve reference values for future studies on Twenty healthy, young adult volunteers without dysfunction were...
The aim of this investigation was to study the effect intra-articular (i.a.) corticosteroid injections (IACIs) in temporomandibular joint (TMJ) on mandibular development antigen-induced TMJ arthritis. Ten-week-old female New Zealand white rabbits (n = 42) were randomly divided into four groups: group A, control (no injections); B, placebo (repeated i.a. saline C, untreated arthritis induction arthritis); and D, steroid + IACI). All animals had two tantalum implants inserted right side...
Temporomandibular joint (TMJ) inflammation in patients with juvenile idiopathic arthritis (JIA) may lead to mandibular growth disturbances and interfere optimal muscle function. Orofacial symptoms are common clinical findings relation TMJ adolescence. Knowledge about their manifestation is important for diagnosis, treatment choice, outcome evaluation. The aim of our prospective observational study was evaluate describe the frequency, main complaints, localization arthritis-related orofacial...
Transduction of primer binding site-impaired Akv murine leukemia virus-based retroviral vectors from the packaging cell lines psi-2 and omega E was studied. The efficiency transduction neo marker all mutated constructs found to decrease by 5 6 orders magnitude compared with that wild-type vector. Thirty-two 60 transduced proviruses analyzed harbored a site sequence matching glutamine tRNA primer. Sequence analysis regions flanking revealed distinct pattern nucleotide differences Akv-based...
To compare the inflammatory changes of antigen-induced temporomandibular joint (TMJ) arthritis in rabbits by different histological methods and to evaluate immunomodulatory effect intra-articular corticosteroid injections histologically.35 (10 weeks old) pre-sensibilized with ovalbumin were divided into three groups: a placebo group five (saline), an 15 (ovalbumin) steroid-treated (ovalbumin + corticosteroid). Additionally, seven receiving no sensibilization served as controls....
Structured Abstract Objective Temporomandibular joint ( TMJ ) arthritis in juvenile patients may interfere with optimal function and mouth opening patterns. Clinical assessment of maximal capacity, laterotrusion protrusion is critical to diagnosis, treatment choice evaluation a therapeutic intervention. The aim the study was determine smallest minimal threshold at which differences laterotrusion, between two consecutive observations can be determined. Setting Sample Population Department...
Objectives: Temporomandibular joint (TMJ) inflammation in patients with juvenile idiopathic arthritis (JIA) may interfere optimal and muscle function. Orofacial symptoms are common findings relation to TMJ arthritis. Previous research on management of arthritis-related orofacial JIA has focused pharmacological treatment modalities without involving physical pain strategies. The aim this study was evaluate changes function after stabilization splint treatment.Method: Twenty-eight consecutive...
Temporomandibular joint (TMJ) inflammation in patients with juvenile idiopathic arthritis (JIA) can lead to orofacial pain and malfunction of the TMJ. Intra-articular corticosteroid injections (IACI) have been suggested as a treatment modality against TMJ arthritis-related signs symptoms. However, knowledge effect-durability these remains unanswered. The aim this pilot study was evaluate short long-term effects IACI on symptoms prospective observational based pre-specified clinical...
Summary Assessment of mandibular mobility is an important part the clinical oro‐facial examination paediatric and adolescent patients. The aims present cross‐sectional study were to establish age‐related normative values for in a Scandinavian cohort assess validity universal cut‐off lower ‘normal’ ranges motion. A total 1114 Danish individuals between 4–17 years age included. Maximal mouth opening capacity laterotrusion assessed, each individual, according standardised measurement protocol....
Recent technological innovations allow for the integration of clear aligner therapy (CAT) with orthognathic surgical procedures, making surgery-first approach (SFOA) a reality. Combining CAT this strategy offers compelling solution both patients and orthodontists seeking faster less visible treatment. Although combination SFOA presents potential advantages practitioners in surgery, it also introduces new challenges. A significant obstacle is effective transfer virtual planned occlusion jaw...