A5103022580- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- MicroRNA in disease regulation
- Genetic Neurodegenerative Diseases
- Neuroscience and Neural Engineering
- Neuroscience and Neuropharmacology Research
- Cancer-related molecular mechanisms research
- Advanced MRI Techniques and Applications
- Neuropeptides and Animal Physiology
- Cerebral Palsy and Movement Disorders
- Diabetic Foot Ulcer Assessment and Management
- Breast Lesions and Carcinomas
- NF-κB Signaling Pathways
- Neurotransmitter Receptor Influence on Behavior
- Balance, Gait, and Falls Prevention
- Regulation of Appetite and Obesity
- Mesenchymal stem cell research
- Cancer Treatment and Pharmacology
- Stress Responses and Cortisol
- Cancer, Stress, Anesthesia, and Immune Response
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Psoriasis: Treatment and Pathogenesis
- Pharmacological Receptor Mechanisms and Effects
Guangzhou Medical University
2013-2024
Second Affiliated Hospital of Guangzhou Medical University
2013-2024
Second Military Medical University
2009-2020
Changhai Hospital
2006-2020
Soochow University
2015-2018
Xuzhou Medical College
2014-2018
Second People’s Hospital of Huai’an
2014-2018
Second Affiliated Hospital of Soochow University
2018
Xinyu University
2015
The Wallace H. Coulter Department of Biomedical Engineering
2015
Although deep brain stimulation (DBS) is nonablative, it may give rise to many complications. In order identify and reduce factors contributing the complications, we performed a retrospective analysis of patients who received DBS in our institution over 9-year period from March 2000 December 2008.Included this study were 161 (85 male 76 female). Data these collected analyzed with respect complications potentially related complications.A total 25 surgical hardware-related occurred 24...
To evaluate the potential benefits of Bacteroides fragilis 839 (BF839), a next-generation probiotics, in reducing myelosuppression and gastrointestinal toxicity associated with chemotherapy breast cancer patient.
Objective This study aimed to analyze the risk factors of intracranial hemorrhage (ICH) after deep brain stimulation (DBS) for idiopathic Parkinson’s disease (PD). Methods Patients who received DBS from March 2014 December 2016 were retrospectively analyzed. The index was derived by combining hemorrhagic volume and clinical manifestations ICH. All patients with IHC followed up 2 years. Results Computed tomography showed 13 events ICH in 11 (nine cases subthalamic nucleus), including eight...
Deep brain stimulation (DBS) is an effective treatment for patients with Parkinson's disease (PD). On time follow-up and timely programing of symptoms are important measures to maintain the effectiveness DBS. Due highly contagious nature 2019-nCoV, were quarantined. With help Internet technologies, we continued provide motor non-motor symptom assessment remote programming services postsurgical PD-DBS during this extraordinary period. A retrospective analysis was performed on who could not...
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease, but whether process influences pharmacodynamics of propofol remains unclear. We aimed to evaluate effect PD on propofol. A total 31 patients undergoing surgical treatment (PD group) and pair-controlled non-PD intracranial surgery (NPD were recruited investigate requirement for unconsciousness induction. Unconsciousness was induced in all with target-controlled infusion The concentration at which compared between...
Granulomatous lobular mastitis (GLM) is a chronic inflammatory breast condition that characterized by granulomatous inflammation. GLM remains refractory disease due to its failure respond routine anti‑inflammatory therapies and high recurrence rate. Thus, the present study aimed investigate application of local heat therapy in as potential therapeutic strategy. The results revealed was associated with shortened remission time for GLM, while rates were similar those existing therapies. median...
Background: Src associated with mitosis of 68 kDa (Sam68), is often highly expressed in human cancers. Overexpression Sam68 has been shown to be correlated poor survival prognosis some cancer patients. However, little known whether plays a role promoting metastasis breast cancer. Materials and Methods: The expression protein tissue was detected by immunohistochemistry. Trans-well assay, wound-healing, real-time PCR Western blotting analysis were used detect the effect on EMT or...
Electroconvulsive therapy (ECT) has known beneficial effects on the core motor symptoms of Parkinson's disease (PD), likely through induction dopamine release and sensitivity receptors. Mesenchymal stem cells (MSCs) can salvage loss in PD their differentiation into dopaminergic neurons. However, it is not if combined ECT MSC transplantation may have a synergistic effect against PD. Here, we showed that significantly increased transplanted MSCs neurons...
Objectives . To analyze the hyperhidrosis neural network structure induced by subthalamic nucleus (STN) - deep brain stimulation (DBS). Materials and Methods Patients with Parkinson’s disease treated STN-DBS in Changhai Hospital between July 1, 2015, December 2016, were analyzed retrospectively. Using records of side effects intraoperative macrostimulation test, patients skin sweats selected as sweating group. Based on number cases group, same was randomly from other without to form control...
Objectives: To determine the short- and medium-term therapeutic effects of subthalamic nucleus (STN) deep brain stimulation (DBS) on restless legs syndrome (RLS) in patients with Parkinson’s disease (PD) to study optimal position activated contacts for RLS symptoms. Methods: We preoperatively postoperatively assessed PD Patients undergoing STN-DBS. Additionally, we recorded parameters that induced or relieved symptoms during a follow-up. Finally, reconstructed contacts’ reduced Results: 363...
Patients with Parkinson's disease have symptom of walking disorders which can be alleviated by surgery. By evaluating gait kinematics, the effect medical treatment quantitatively assessed. In this paper, a method using image markers based on rigid body was introduced to set anatomy key points human lower limbs, efficiently reduced measurement errors coming from skin movement during motions. Eleven (PD) patients subthalamic nucleus deep brain stimulation (STN-DBS) implantation and five...
Abnormal destruction of the components articular extracellular matrix (ECM) such as type II collagen and aggrecan caused by advanced glycation end products (AGEs) has been considered one pathological characteristics osteoarthritis (OA). Receptor-interacting protein 1 (RIP1), an important serine/threonine kinase, possesses a variety biological functions including cell proliferation, survival death. The physiological roles RIP1 in OA have not reported before. Here, we found that AGEs increased...
Objective . To explore the optimal time points for deep brain stimulation (DBS) on treatment of morphine addiction and its possible mechanisms by investigating how high‐frequency (HFS) in bilateral nucleus accumbens (NAc) at different influences addictive behaviors rats with drug addiction. Methods The were randomly divided into extinction group ( n = 20) postextinction 20). Ten treated using 120 Hz HFS during stage while another 10 pseudostimulation served as control group. CPP scores...